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Items: 1 to 20 of 77

1.

The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia.

Moreno-Miralles I, Pan L, Keates-Baleeiro J, Durst-Goodwin K, Yang C, Kim HG, Thompson MA, Klug CA, Cleveland JL, Hiebert SW.

J Biol Chem. 2005 Dec 2;280(48):40097-103. Epub 2005 Sep 30.

2.

Mechanisms of transcriptional repression by the t(8;21)-, t(12;21)-, and inv(16)-encoded fusion proteins.

Heibert SW, Lutterbach B, Durst K, Wang L, Linggi B, Wu S, Wood L, Amann J, King D, Hou Y.

Cancer Chemother Pharmacol. 2001 Aug;48 Suppl 1:S31-4. Review.

PMID:
11587363
3.

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW.

Nat Med. 2002 Jul;8(7):743-50. Epub 2002 Jun 24.

PMID:
12091906
4.

An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice.

Grisolano JL, O'Neal J, Cain J, Tomasson MH.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9506-11. Epub 2003 Jul 24.

5.

c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

Luo H, Li Q, O'Neal J, Kreisel F, Le Beau MM, Tomasson MH.

Blood. 2005 Oct 1;106(7):2452-61. Epub 2005 Jun 21.

6.

Acceleration of G(1) cooperates with core binding factor beta-smooth muscle myosin heavy chain to induce acute leukemia in mice.

Yang Y, Wang W, Cleaves R, Zahurak M, Cheng L, Civin CI, Friedman AD.

Cancer Res. 2002 Apr 15;62(8):2232-5.

7.

LPXN, a member of the paxillin superfamily, is fused to RUNX1 in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation.

Dai HP, Xue YQ, Zhou JW, Li AP, Wu YF, Pan JL, Wang Y, Zhang J.

Genes Chromosomes Cancer. 2009 Dec;48(12):1027-36. doi: 10.1002/gcc.20704.

PMID:
19760607
8.

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.

Durst KL, Lutterbach B, Kummalue T, Friedman AD, Hiebert SW.

Mol Cell Biol. 2003 Jan;23(2):607-19.

9.

The t(8;21) fusion protein contacts co-repressors and histone deacetylases to repress the transcription of the p14ARF tumor suppressor.

Hiebert SW, Reed-Inderbitzin EF, Amann J, Irvin B, Durst K, Linggi B.

Blood Cells Mol Dis. 2003 Mar-Apr;30(2):177-83. Review.

PMID:
12732181
10.

Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11.

Kundu M, Chen A, Anderson S, Kirby M, Xu L, Castilla LH, Bodine D, Liu PP.

Blood. 2002 Oct 1;100(7):2449-56.

11.

Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells.

Liu PP, Wijmenga C, Hajra A, Blake TB, Kelley CA, Adelstein RS, Bagg A, Rector J, Cotelingam J, Willman CL, Collins FS.

Genes Chromosomes Cancer. 1996 Jun;16(2):77-87. Erratum in: Genes Chromosomes Cancer 1997 Jan;18(1):71.

PMID:
8818654
12.

Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22).

Zhao W, Claxton DF, Medeiros LJ, Lu D, Vadhan-Raj S, Kantarjian HM, Nguyen MH, Bueso-Ramos CE.

Am J Surg Pathol. 2006 Nov;30(11):1436-44.

PMID:
17063086
13.

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H.

Blood. 2006 Apr 15;107(8):3303-12. Epub 2005 Dec 27.

14.

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant.

Colombo E, Martinelli P, Zamponi R, Shing DC, Bonetti P, Luzi L, Volorio S, Bernard L, Pruneri G, Alcalay M, Pelicci PG.

Cancer Res. 2006 Mar 15;66(6):3044-50.

15.

Low p53 expression of acute myelocytic leukemia cells with t(8;21) chromosome abnormality: association with low p14(ARF) expression.

Shikami M, Miwa H, Nishii K, Kyo T, Tanaka I, Shiku H, Kita K, Nitta M.

Leuk Res. 2006 Apr;30(4):379-83. Epub 2005 Sep 12.

PMID:
16162359
16.

[Development of human myeloid leukemia-like phenotype in NUP98-PMX1 transgenic mice].

Wang Y, Gu MM, Tan Y, Lu SY, Wang L, Kong H, Sun YP, Lu ZY, Chen SJ, Wang ZY, Wang ZG.

Zhonghua Xue Ye Xue Za Zhi. 2004 May;25(5):262-5. Chinese.

PMID:
15182531
17.

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia.

Jankovic D, Gorello P, Liu T, Ehret S, La Starza R, Desjobert C, Baty F, Brutsche M, Jayaraman PS, Santoro A, Mecucci C, Schwaller J.

Blood. 2008 Jun 15;111(12):5672-82. doi: 10.1182/blood-2007-09-108175. Epub 2008 Apr 3.

18.

Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11.

Shigesada K, van de Sluis B, Liu PP.

Oncogene. 2004 May 24;23(24):4297-307. Review.

PMID:
15156186
19.

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG.

J Clin Invest. 2004 Feb;113(4):528-38.

20.

Changes in p19Arf localization accompany apoptotic crisis during pre-B-cell transformation by Abelson murine leukemia virus.

Zimmerman RS, Rosenberg N.

J Virol. 2008 Sep;82(17):8383-91. doi: 10.1128/JVI.00348-08. Epub 2008 Jun 25.

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