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Items: 1 to 20 of 250

1.

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.

Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW.

J Biol Chem. 2005 Nov 25;280(47):39653-64. Epub 2005 Sep 28.

2.

LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.

Tamehiro N, Park MH, Hawxhurst V, Nagpal K, Adams ME, Zannis VI, Golenbock DT, Fitzgerald ML.

Biochemistry. 2015 Nov 24;54(46):6931-41. doi: 10.1021/acs.biochem.5b00894. Epub 2015 Nov 9.

3.

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.

Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML.

Biochemistry. 2008 Jun 10;47(23):6138-47. doi: 10.1021/bi800182t. Epub 2008 May 17.

4.

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.

Fitzgerald ML, Okuhira K, Short GF 3rd, Manning JJ, Bell SA, Freeman MW.

J Biol Chem. 2004 Nov 12;279(46):48477-85. Epub 2004 Sep 3.

5.

Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.

Okuhira K, Fitzgerald ML, Tamehiro N, Ohoka N, Suzuki K, Sawada J, Naito M, Nishimaki-Mogami T.

J Biol Chem. 2010 May 21;285(21):16369-77. doi: 10.1074/jbc.M109.061424. Epub 2010 Mar 26.

6.

Alpha1-syntrophin modulates turnover of ABCA1.

Munehira Y, Ohnishi T, Kawamoto S, Furuya A, Shitara K, Imamura M, Yokota T, Takeda S, Amachi T, Matsuo M, Kioka N, Ueda K.

J Biol Chem. 2004 Apr 9;279(15):15091-5. Epub 2004 Jan 13.

7.

Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells.

Oram JF, Wolfbauer G, Vaughan AM, Tang C, Albers JJ.

J Biol Chem. 2003 Dec 26;278(52):52379-85. Epub 2003 Oct 14.

9.

The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex.

Buechler C, Boettcher A, Bared SM, Probst MC, Schmitz G.

Biochem Biophys Res Commun. 2002 May 3;293(2):759-65.

PMID:
12054535
10.

OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages.

Yan D, Mäyränpää MI, Wong J, Perttilä J, Lehto M, Jauhiainen M, Kovanen PT, Ehnholm C, Brown AJ, Olkkonen VM.

J Biol Chem. 2008 Jan 4;283(1):332-40. Epub 2007 Nov 8.

11.

HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export.

Du XM, Kim MJ, Hou L, Le Goff W, Chapman MJ, Van Eck M, Curtiss LK, Burnett JR, Cartland SP, Quinn CM, Kockx M, Kontush A, Rye KA, Kritharides L, Jessup W.

Circ Res. 2015 Mar 27;116(7):1133-42. doi: 10.1161/CIRCRESAHA.116.305485. Epub 2015 Jan 14. Erratum in: Circ Res. 2015 Jul 17;117(3):e40.

12.

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

Wang N, Lan D, Chen W, Matsuura F, Tall AR.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9774-9. Epub 2004 Jun 21.

13.

Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein.

Favari E, Lee M, Calabresi L, Franceschini G, Zimetti F, Bernini F, Kovanen PT.

J Biol Chem. 2004 Mar 12;279(11):9930-6. Epub 2003 Dec 29.

14.

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1.

Ramirez CM, Dávalos A, Goedeke L, Salerno AG, Warrier N, Cirera-Salinas D, Suárez Y, Fernández-Hernando C.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2707-14. doi: 10.1161/ATVBAHA.111.232066.

15.

Statin-induced decrease in ATP-binding cassette transporter A1 expression via microRNA33 induction may counteract cholesterol efflux to high-density lipoprotein.

Niesor EJ, Schwartz GG, Perez A, Stauffer A, Durrwell A, Bucklar-Suchankova G, Benghozi R, Abt M, Kallend D.

Cardiovasc Drugs Ther. 2015 Feb;29(1):7-14. doi: 10.1007/s10557-015-6570-0.

PMID:
25749868
16.

Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI.

Lorenzi I, von Eckardstein A, Cavelier C, Radosavljevic S, Rohrer L.

J Mol Med (Berl). 2008 Feb;86(2):171-83. Epub 2007 Oct 1.

PMID:
17906976
17.

Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages.

Linder MD, Mäyränpää MI, Peränen J, Pietilä TE, Pietiäinen VM, Uronen RL, Olkkonen VM, Kovanen PT, Ikonen E.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):883-8. doi: 10.1161/ATVBAHA.108.179481. Epub 2009 Mar 19.

18.

The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux.

Porsch-Ozcurumez M, Langmann T, Heimerl S, Borsukova H, Kaminski WE, Drobnik W, Honer C, Schumacher C, Schmitz G.

J Biol Chem. 2001 Apr 13;276(15):12427-33. Epub 2001 Jan 22.

19.

TGF-beta1 up-regulates expression of ABCA1, ABCG1 and SR-BI through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells.

Hu YW, Wang Q, Ma X, Li XX, Liu XH, Xiao J, Liao DF, Xiang J, Tang CK.

J Atheroscler Thromb. 2010 May;17(5):493-502. Epub 2010 Jan 7.

20.

Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages.

Shridas P, Bailey WM, Gizard F, Oslund RC, Gelb MH, Bruemmer D, Webb NR.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):2014-21. doi: 10.1161/ATVBAHA.110.210237.

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