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Items: 1 to 20 of 101

1.

Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha.

Chen M, Beaven S, Tontonoz P.

J Lipid Res. 2005 Dec;46(12):2570-9. Epub 2005 Sep 16.

2.

Differential expression and function of alternative splicing variants of human liver X receptor α.

Endo-Umeda K, Uno S, Fujimori K, Naito Y, Saito K, Yamagishi K, Jeong Y, Miyachi H, Tokiwa H, Yamada S, Makishima M.

Mol Pharmacol. 2012 Jun;81(6):800-10. doi: 10.1124/mol.111.077206. Epub 2012 Mar 7.

3.

Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein.

Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA.

J Biol Chem. 2001 Oct 19;276(42):39438-47. Epub 2001 Aug 10. Erratum in: J Biol Chem 2002 May 10;277(19):17375.

4.

Transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish.

Archer A, Lauter G, Hauptmann G, Mode A, Gustafsson JA.

Dev Dyn. 2008 Apr;237(4):1090-8. doi: 10.1002/dvdy.21476.

5.

Molecular basis for repression of liver X receptor-mediated gene transcription by receptor-interacting protein 140.

Jakobsson T, Osman W, Gustafsson JA, Zilliacus J, Wärnmark A.

Biochem J. 2007 Jul 1;405(1):31-9.

6.

Identification of human low-density lipoprotein receptor as a novel target gene regulated by liver X receptor alpha.

Ishimoto K, Tachibana K, Sumitomo M, Omote S, Hanano I, Yamasaki D, Watanabe Y, Tanaka T, Hamakubo T, Sakai J, Kodama T, Doi T.

FEBS Lett. 2006 Sep 4;580(20):4929-33. Epub 2006 Aug 14.

7.

Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages.

Torra IP, Ismaili N, Feig JE, Xu CF, Cavasotto C, Pancratov R, Rogatsky I, Neubert TA, Fisher EA, Garabedian MJ.

Mol Cell Biol. 2008 Apr;28(8):2626-36. doi: 10.1128/MCB.01575-07. Epub 2008 Feb 4.

8.

Liver X receptor-alpha gene expression is positively regulated by thyroid hormone.

Hashimoto K, Matsumoto S, Yamada M, Satoh T, Mori M.

Endocrinology. 2007 Oct;148(10):4667-75. Epub 2007 Jul 12.

PMID:
17628006
9.

Unliganded thyroid hormone receptor-beta1 represses liver X receptor alpha/oxysterol-dependent transactivation.

Kawai K, Sasaki S, Morita H, Ito T, Suzuki S, Misawa H, Nakamura H.

Endocrinology. 2004 Dec;145(12):5515-24. Epub 2004 Aug 19.

PMID:
15319359
11.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.

Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1255-67. Epub 2003 May 1.

PMID:
12730332
12.

Ligand-activated PPARbeta efficiently represses the induction of LXR-dependent promoter activity through competition with RXR.

Matsusue K, Miyoshi A, Yamano S, Gonzalez FJ.

Mol Cell Endocrinol. 2006 Aug 15;256(1-2):23-33.

13.

The nuclear receptor LXR is a glucose sensor.

Mitro N, Mak PA, Vargas L, Godio C, Hampton E, Molteni V, Kreusch A, Saez E.

Nature. 2007 Jan 11;445(7124):219-23. Epub 2006 Dec 24.

PMID:
17187055
14.

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor.

Costet P, Luo Y, Wang N, Tall AR.

J Biol Chem. 2000 Sep 8;275(36):28240-5.

15.

Functional genomics of blood cellular LXR-alpha gene in human coronary heart disease.

Dave VP, Kaul D, Sharma Y, Bhattacharya R.

J Mol Cell Cardiol. 2009 Apr;46(4):536-44. doi: 10.1016/j.yjmcc.2008.12.020. Epub 2009 Jan 13.

PMID:
19211025
16.

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements.

Yoshikawa T, Shimano H, Yahagi N, Ide T, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Takahashi A, Sone H, Osuga Ji J, Gotoda T, Ishibashi S, Yamada N.

J Biol Chem. 2002 Jan 18;277(3):1705-11. Epub 2001 Nov 2.

17.

Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines.

Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

J Lipid Res. 2005 Nov;46(11):2377-87. Epub 2005 Aug 16.

18.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54. Epub 2003 May 1.

PMID:
12730331
19.

Mutations in the AF-2 region abolish ligand-induced intranuclear immobilization of the liver X receptor alpha.

Prüfer K, Hernandez C, Gilbreath M.

Exp Cell Res. 2008 Aug 15;314(14):2652-60. doi: 10.1016/j.yexcr.2008.05.005. Epub 2008 May 27.

PMID:
18599038
20.

Liver X receptor ligands suppress ubiquitination and degradation of LXRalpha by displacing BARD1/BRCA1.

Kim KH, Yoon JM, Choi AH, Kim WS, Lee GY, Kim JB.

Mol Endocrinol. 2009 Apr;23(4):466-74. doi: 10.1210/me.2008-0295. Epub 2009 Jan 22.

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