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Items: 1 to 20 of 154

1.

Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors.

Sarret P, Esdaile MJ, Perron A, Martinez J, Stroh T, Beaudet A.

J Neurosci. 2005 Sep 7;25(36):8188-96.

2.

Evidence for a role of NTS2 receptors in the modulation of tonic pain sensitivity.

Roussy G, Dansereau MA, Baudisson S, Ezzoubaa F, Belleville K, Beaudet N, Martinez J, Richelson E, Sarret P.

Mol Pain. 2009 Jul 6;5:38. doi: 10.1186/1744-8069-5-38.

3.

Spinal NTS1 receptors regulate nociceptive signaling in a rat formalin tonic pain model.

Roussy G, Dansereau MA, Doré-Savard L, Belleville K, Beaudet N, Richelson E, Sarret P.

J Neurochem. 2008 May;105(4):1100-14. doi: 10.1111/j.1471-4159.2007.05205.x. Epub 2007 Dec 25.

4.

NT69L, a novel analgesic, shows synergy with morphine.

Boules M, Shaw A, Liang Y, Barbut D, Richelson E.

Brain Res. 2009 Oct 19;1294:22-8. doi: 10.1016/j.brainres.2009.07.086. Epub 2009 Aug 3.

PMID:
19651107
5.

NTS1 and NTS2 mediate analgesia following neurotensin analog treatment in a mouse model for visceral pain.

Smith KE, Boules M, Williams K, Richelson E.

Behav Brain Res. 2012 Jun 15;232(1):93-7. doi: 10.1016/j.bbr.2012.03.044. Epub 2012 Apr 5.

PMID:
22504145
6.

Pharmacology and functional properties of NTS2 neurotensin receptors in cerebellar granule cells.

Sarret P, Gendron L, Kilian P, Nguyen HM, Gallo-Payet N, Payet MD, Beaudet A.

J Biol Chem. 2002 Sep 27;277(39):36233-43. Epub 2002 Jun 25.

7.

Intrathecal administration of NTS1 agonists reverses nociceptive behaviors in a rat model of neuropathic pain.

Guillemette A, Dansereau MA, Beaudet N, Richelson E, Sarret P.

Eur J Pain. 2012 Apr;16(4):473-84. doi: 10.1016/j.ejpain.2011.07.008.

PMID:
22396077
8.

Involvement of NTS2 receptors in stress-induced analgesia.

Lafrance M, Roussy G, Belleville K, Maeno H, Beaudet N, Wada K, Sarret P.

Neuroscience. 2010 Mar 17;166(2):639-52. doi: 10.1016/j.neuroscience.2009.12.042. Epub 2009 Dec 24.

PMID:
20035838
9.

Low-affinity neurotensin receptor (NTS2) signaling: internalization-dependent activation of extracellular signal-regulated kinases 1/2.

Gendron L, Perron A, Payet MD, Gallo-Payet N, Sarret P, Beaudet A.

Mol Pharmacol. 2004 Dec;66(6):1421-30. Epub 2004 Sep 10.

PMID:
15361549
10.

Interactions between NTS2 neurotensin and opioid receptors on two nociceptive responses assessed on the hot plate test in mice.

Bredeloux P, Costentin J, Dubuc I.

Behav Brain Res. 2006 Dec 15;175(2):399-407. Epub 2006 Oct 30.

PMID:
17074405
11.

Spinal NTS2 receptor activation reverses signs of neuropathic pain.

Tétreault P, Beaudet N, Perron A, Belleville K, René A, Cavelier F, Martinez J, Stroh T, Jacobi AM, Rose SD, Behlke MA, Sarret P.

FASEB J. 2013 Sep;27(9):3741-52. doi: 10.1096/fj.12-225540. Epub 2013 Jun 11.

PMID:
23756650
12.

Neurotensin inhibits background K+ channels and facilitates glutamatergic transmission in rat spinal cord dorsal horn.

Kadiri N, Rodeau JL, Schlichter R, Hugel S.

Eur J Neurosci. 2011 Oct;34(8):1230-40. doi: 10.1111/j.1460-9568.2011.07846.x. Epub 2011 Sep 21.

PMID:
21936876
13.

Neurotensin activation of the NTR1 on spinally-projecting serotonergic neurons in the rostral ventromedial medulla is antinociceptive.

Buhler AV, Choi J, Proudfit HK, Gebhart GF.

Pain. 2005 Mar;114(1-2):285-94. Epub 2005 Jan 26.

PMID:
15733655
14.

Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptors.

Perron A, Sharif N, Gendron L, Lavallée M, Stroh T, Mazella J, Beaudet A.

Biochem Biophys Res Commun. 2006 May 12;343(3):799-808. Epub 2006 Mar 20.

PMID:
16564027
15.

Analgesic synergy of neurotensin receptor subtype 2 agonist NT79 and morphine.

Boules M, Johnston H, Tozy J, Smith K, Li Z, Richelson E.

Behav Pharmacol. 2011 Sep;22(5-6):573-81. doi: 10.1097/FBP.0b013e3283474a3a.

PMID:
21691202
16.

Spinal mu-opioid receptor-expressing dorsal horn neurons: role in nociception and morphine antinociception.

Kline RH 4th, Wiley RG.

J Neurosci. 2008 Jan 23;28(4):904-13. doi: 10.1523/JNEUROSCI.4452-07.2008.

17.

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2.

Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpré JM, Runyon SP, Decker AM, Gilmour BP, Sarret P.

ACS Chem Neurosci. 2016 Sep 21;7(9):1225-31. doi: 10.1021/acschemneuro.6b00097. Epub 2016 Jul 13.

PMID:
27359371
18.

NTS2 modulates the intracellular distribution and trafficking of NTS1 via heterodimerization.

Perron A, Sharif N, Sarret P, Stroh T, Beaudet A.

Biochem Biophys Res Commun. 2007 Feb 16;353(3):582-90. Epub 2006 Dec 18.

PMID:
17188644
19.

The spinal muscarinic M(1) receptors and GABA(A) receptors contribute to the McN-A-343-induced antinociceptive effects during thermal stimulation of mice.

Honda K, Horikawa K, Ando S, Koga K, Kawata S, Migita K, Takano Y.

J Pharmacol Sci. 2008 Dec;108(4):472-9. Epub 2008 Dec 5.

20.

Identification and functional characterization of a 5-transmembrane domain variant isoform of the NTS2 neurotensin receptor in rat central nervous system.

Perron A, Sarret P, Gendron L, Stroh T, Beaudet A.

J Biol Chem. 2005 Mar 18;280(11):10219-27. Epub 2005 Jan 6.

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