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Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.

Sylwester AW, Mitchell BL, Edgar JB, Taormina C, Pelte C, Ruchti F, Sleath PR, Grabstein KH, Hosken NA, Kern F, Nelson JA, Picker LJ.

J Exp Med. 2005 Sep 5;202(5):673-85.


Contemporaneous fluctuations in T cell responses to persistent herpes virus infections.

Crough T, Burrows JM, Fazou C, Walker S, Davenport MP, Khanna R.

Eur J Immunol. 2005 Jan;35(1):139-49.


Polyfunctional analysis of human cytomegalovirus (HCMV)-specific CD4(+) and CD8 (+) memory T-cells in HCMV-seropositive healthy subjects following different stimuli.

Gabanti E, Bruno F, Fornara C, Bernuzzi S, Lilleri D, Gerna G.

J Clin Immunol. 2014 Nov;34(8):999-1008. doi: 10.1007/s10875-014-0093-5. Epub 2014 Sep 18.


Reference values for CD4+ and CD8+ T lymphocytes with naïve or memory phenotype and their association with mortality in the elderly.

Provinciali M, Moresi R, Donnini A, Lisa RM.

Gerontology. 2009;55(3):314-21. doi: 10.1159/000199451. Epub 2009 Feb 4.


Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry.

Suni MA, Picker LJ, Maino VC.

J Immunol Methods. 1998 Mar 1;212(1):89-98.


Human cytomegalovirus (CMV)-specific CD8+ T cell responses are reduced in HIV-infected individuals with a history of CMV disease despite CD4+ T cell recovery.

Singh KP, Howard JL, Wild SP, Jones SL, Hoy J, Lewin SR.

Clin Immunol. 2007 Aug;124(2):200-6. Epub 2007 Jun 15.


Cross-reactive recognition of human and primate cytomegalovirus sequences by human CD4 cytotoxic T lymphocytes specific for glycoprotein B and H.

Elkington R, Shoukry NH, Walker S, Crough T, Fazou C, Kaur A, Walker CM, Khanna R.

Eur J Immunol. 2004 Nov;34(11):3216-26.


Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses.

Ramduth D, Chetty P, Mngquandaniso NC, Nene N, Harlow JD, Honeyborne I, Ntumba N, Gappoo S, Henry C, Jeena P, Addo MM, Altfeld M, Brander C, Day C, Coovadia H, Kiepiela P, Goulder P, Walker B.

J Infect Dis. 2005 Nov 1;192(9):1588-96. Epub 2005 Sep 30.


Cognate CD4 help is essential for the reactivation and expansion of CD8 memory T cells directed against the hematopoietic cell-specific dominant minor histocompatibility antigen, H60.

Ryu SJ, Jung KM, Yoo HS, Kim TW, Kim S, Chang J, Choi EY.

Blood. 2009 Apr 30;113(18):4273-80. doi: 10.1182/blood-2008-09-181263. Epub 2009 Jan 12.


T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells.

Fasth AE, Dastmalchi M, Rahbar A, Salomonsson S, Pandya JM, Lindroos E, Nennesmo I, Malmberg KJ, Söderberg-Nauclér C, Trollmo C, Lundberg IE, Malmström V.

J Immunol. 2009 Oct 1;183(7):4792-9. doi: 10.4049/jimmunol.0803688. Epub 2009 Sep 14.


Does memory improve with age? CD85j (ILT-2/LIR-1) expression on CD8 T cells correlates with 'memory inflation' in human cytomegalovirus infection.

Northfield J, Lucas M, Jones H, Young NT, Klenerman P.

Immunol Cell Biol. 2005 Apr;83(2):182-8.


Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.

Welters MJ, Kenter GG, Piersma SJ, Vloon AP, Löwik MJ, Berends-van der Meer DM, Drijfhout JW, Valentijn AR, Wafelman AR, Oostendorp J, Fleuren GJ, Offringa R, Melief CJ, van der Burg SH.

Clin Cancer Res. 2008 Jan 1;14(1):178-87. doi: 10.1158/1078-0432.CCR-07-1880.


Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells.

van Leeuwen EM, Koning JJ, Remmerswaal EB, van Baarle D, van Lier RA, ten Berge IJ.

J Immunol. 2006 Oct 15;177(8):4998-5005.


The role of the CD95, CD38 and TGFbeta1 during active human cytomegalovirus infection in liver transplantation.

Wang Y, Liu Y, Zhang Y, Peng L, Ma J, Tang Z, Gao W, Zhu Z, Yao Z.

Cytokine. 2006 Aug;35(3-4):193-9. Epub 2006 Oct 5.


Cytomegalovirus-specific CD4 T-cell and glycoprotein B specific antibody response in recipients of allogenic stem cell transplantation.

Ludwig B, Kraus FB, Kipp M, Preiser W, Schwerdtfeger R, Doerr HW, Buxbaum S.

J Clin Virol. 2006 Feb;35(2):160-6. Epub 2005 Aug 19.


Diverse specificities, phenotypes, and antiviral activities of cytomegalovirus-specific CD8+ T cells.

Jackson SE, Mason GM, Okecha G, Sissons JG, Wills MR.

J Virol. 2014 Sep;88(18):10894-908. doi: 10.1128/JVI.01477-14. Epub 2014 Jul 9.


Human cytomegalovirus-specific CD4(+) and CD8(+) T-cell response determination: comparison of short-term (24h) assays vs long-term (7-day) infected dendritic cell assay in the immunocompetent and the immunocompromised host.

Zelini P, Lilleri D, Comolli G, Rognoni V, Chiesa A, Fornara C, Locatelli F, Meloni F, Gerna G.

Clin Immunol. 2010 Aug;136(2):269-81. doi: 10.1016/j.clim.2010.04.008. Epub 2010 May 20.


Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis.

Yamashita K, Horwitz ME, Kwatemaa A, Nomicos E, Castro K, Sokolic R, Foster SF, Garofalo M, Choi U, Ryherd M, Brown MR, Leitman SF, Wayne AS, Fowler DH, Bishop MR, Childs RW, Barrett AJ, Pavletic SZ, Malech HL.

Biol Blood Marrow Transplant. 2006 Jan;12(1 Suppl 2):22-30.


Cytomegalovirus-specific T-cell responses and viral replication in kidney transplant recipients.

Egli A, Binet I, Binggeli S, Jäger C, Dumoulin A, Schaub S, Steiger J, Sester U, Sester M, Hirsch HH.

J Transl Med. 2008 Jun 9;6:29. doi: 10.1186/1479-5876-6-29.


Normalizing ELISPOT responses to T-cell counts: a novel approach for quantification of HCMV-specific CD4(+) and CD8(+) T-cell responses in kidney transplant recipients.

Calarota SA, Chiesa A, Scaramuzzi L, Adzasehoun KM, Comolli G, Mangione F, Esposito P, Baldanti F.

J Clin Virol. 2014 Sep;61(1):65-73. doi: 10.1016/j.jcv.2014.05.017. Epub 2014 Jun 4.


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