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Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo.

Gao L, Zhang L, Hu J, Li F, Shao Y, Zhao D, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ.

Clin Cancer Res. 2005 Sep 1;11(17):6333-41.


Inhibition of STAT3 expression by siRNA suppresses growth and induces apoptosis in laryngeal cancer cells.

Gao LF, Xu DQ, Wen LJ, Zhang XY, Shao YT, Zhao XJ.

Acta Pharmacol Sin. 2005 Mar;26(3):377-83.


[Inhibitory effect of silencing STAT3 gene with short hairpin RNA mediated by polyamidoamine dendrimers on growth of prostate cancer].

Zhao WM, Xiu YC, Xu Y, Wang YM, Cheng ZK, Yu Q, Kong DL.

Zhonghua Zhong Liu Za Zhi. 2007 Aug;29(8):575-9. Chinese.


RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells.

Lee SO, Lou W, Qureshi KM, Mehraein-Ghomi F, Trump DL, Gao AC.

Prostate. 2004 Sep 1;60(4):303-9.


Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3.

Hellsten R, Johansson M, Dahlman A, Dizeyi N, Sterner O, Bjartell A.

Prostate. 2008 Feb 15;68(3):269-80. doi: 10.1002/pros.20699.


Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo.

Dagvadorj A, Kirken RA, Leiby B, Karras J, Nevalainen MT.

Clin Cancer Res. 2008 Mar 1;14(5):1317-24. doi: 10.1158/1078-0432.CCR-07-2024.


Effects of plasmid-based Stat3-specific short hairpin RNA and GRIM-19 on PC-3M tumor cell growth.

Zhang L, Gao L, Li Y, Lin G, Shao Y, Ji K, Yu H, Hu J, Kalvakolanu DV, Kopecko DJ, Zhao X, Xu DQ.

Clin Cancer Res. 2008 Jan 15;14(2):559-68. doi: 10.1158/1078-0432.CCR-07-1176.


Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

Hu H, Lee HJ, Jiang C, Zhang J, Wang L, Zhao Y, Xiang Q, Lee EO, Kim SH, Lü J.

Mol Cancer Ther. 2008 Sep;7(9):2681-91. doi: 10.1158/1535-7163.MCT-08-0456. Erratum in: Mol Cancer Ther. 2008 Nov;7(11):3654.


Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells.

Mora LB, Buettner R, Seigne J, Diaz J, Ahmad N, Garcia R, Bowman T, Falcone R, Fairclough R, Cantor A, Muro-Cacho C, Livingston S, Karras J, Pow-Sang J, Jove R.

Cancer Res. 2002 Nov 15;62(22):6659-66.


Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice.

Ling X, Arlinghaus RB.

Cancer Res. 2005 Apr 1;65(7):2532-6. Erratum in: Cancer Res. 2005 Jun 1;65(11):4969.


Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice.

Zhang X, Zhang J, Wang L, Wei H, Tian Z.

BMC Cancer. 2007 Aug 4;7:149.


The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter.

Barré B, Vigneron A, Coqueret O.

J Biol Chem. 2005 Apr 22;280(16):15673-81. Epub 2005 Jan 26.


Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.

Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H.

Oncogene. 2002 Mar 27;21(13):2000-8.


Small interfering RNA-directed targeting of Toll-like receptor 4 inhibits human prostate cancer cell invasion, survival, and tumorigenicity.

Hua D, Liu MY, Cheng ZD, Qin XJ, Zhang HM, Chen Y, Qin GJ, Liang G, Li JN, Han XF, Liu DX.

Mol Immunol. 2009 Sep;46(15):2876-84. doi: 10.1016/j.molimm.2009.06.016. Epub 2009 Jul 29.


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