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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.

Haase AD, Jaskiewicz L, Zhang H, Lainé S, Sack R, Gatignol A, Filipowicz W.

EMBO Rep. 2005 Oct;6(10):961-7.


Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production.

Christensen HS, Daher A, Soye KJ, Frankel LB, Alexander MR, Lainé S, Bannwarth S, Ong CL, Chung SW, Campbell SM, Purcell DF, Gatignol A.

J Virol. 2007 May;81(10):5121-31. Epub 2007 Mar 14.


HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs.

Daniels SM, Sinck L, Ward NJ, Melendez-Peña CE, Scarborough RJ, Azar I, Rance E, Daher A, Pang KM, Rossi JJ, Gatignol A.

RNA Biol. 2015;12(2):123-35. doi: 10.1080/15476286.2015.1014759.


The role of PACT in the RNA silencing pathway.

Lee Y, Hur I, Park SY, Kim YK, Suh MR, Kim VN.

EMBO J. 2006 Feb 8;25(3):522-32. Epub 2006 Jan 19.


Multiple sensors ensure guide strand selection in human RNAi pathways.

Noland CL, Doudna JA.

RNA. 2013 May;19(5):639-48. doi: 10.1261/rna.037424.112. Epub 2013 Mar 26.


Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

Kok KH, Ng MH, Ching YP, Jin DY.

J Biol Chem. 2007 Jun 15;282(24):17649-57. Epub 2007 Apr 23.


Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing.

Lee HY, Zhou K, Smith AM, Noland CL, Doudna JA.

Nucleic Acids Res. 2013 Jul;41(13):6568-76. doi: 10.1093/nar/gkt361. Epub 2013 May 9.


TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R.

Nature. 2005 Aug 4;436(7051):740-4. Epub 2005 Jun 22.


Deletion of human tarbp2 reveals cellular microRNA targets and cell-cycle function of TRBP.

Kim Y, Yeo J, Lee JH, Cho J, Seo D, Kim JS, Kim VN.

Cell Rep. 2014 Nov 6;9(3):1061-74. doi: 10.1016/j.celrep.2014.09.039. Epub 2014 Oct 23.


HIV-1 TAR RNA subverts RNA interference in transfected cells through sequestration of TAR RNA-binding protein, TRBP.

Bennasser Y, Yeung ML, Jeang KT.

J Biol Chem. 2006 Sep 22;281(38):27674-8. Epub 2006 Aug 3.


Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression.

Daher A, Longuet M, Dorin D, Bois F, Segeral E, Bannwarth S, Battisti PL, Purcell DF, Benarous R, Vaquero C, Meurs EF, Gatignol A.

J Biol Chem. 2001 Sep 7;276(36):33899-905. Epub 2001 Jul 3.


Characterization of the TRBP domain required for dicer interaction and function in RNA interference.

Daniels SM, Melendez-Peña CE, Scarborough RJ, Daher A, Christensen HS, El Far M, Purcell DF, Lainé S, Gatignol A.

BMC Mol Biol. 2009 May 7;10:38. doi: 10.1186/1471-2199-10-38.


The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR.

Dorin D, Bonnet MC, Bannwarth S, Gatignol A, Meurs EF, Vaquero C.

J Biol Chem. 2003 Feb 14;278(7):4440-8. Epub 2002 Dec 9.


Partial reconstitution of the RNAi response in human cells using Drosophila gene products.

Kennedy EM, Kornepati AV, Bogerd HP, Cullen BR.

RNA. 2017 Feb;23(2):153-160. doi: 10.1261/rna.059345.116. Epub 2016 Nov 11.


HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR.

Klase Z, Kale P, Winograd R, Gupta MV, Heydarian M, Berro R, McCaffrey T, Kashanchi F.

BMC Mol Biol. 2007 Jul 30;8:63.


Intracellular localization and routing of miRNA and RNAi pathway components.

Ohrt T, Muetze J, Svoboda P, Schwille P.

Curr Top Med Chem. 2012;12(2):79-88. Review.


Requirements for human Dicer and TRBP in microRNA-122 regulation of HCV translation and RNA abundance.

Zhang C, Huys A, Thibault PA, Wilson JA.

Virology. 2012 Nov 25;433(2):479-88. doi: 10.1016/j.virol.2012.08.039. Epub 2012 Sep 19.


The role of Dicer protein partners in the processing of microRNA precursors.

Koscianska E, Starega-Roslan J, Krzyzosiak WJ.

PLoS One. 2011;6(12):e28548. doi: 10.1371/journal.pone.0028548. Epub 2011 Dec 6.

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