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Conformational changes of pore helix coupled to gating of TRPV5 by protons.

Yeh BI, Kim YK, Jabbar W, Huang CL.

EMBO J. 2005 Sep 21;24(18):3224-34. Epub 2005 Aug 25.


On the role of pore helix in regulation of TRPV5 by extracellular protons.

Yeh BI, Yoon J, Huang CL.

J Membr Biol. 2006;212(3):191-8. Epub 2007 Feb 28.


Mechanism and molecular determinant for regulation of rabbit transient receptor potential type 5 (TRPV5) channel by extracellular pH.

Yeh BI, Sun TJ, Lee JZ, Chen HH, Huang CL.

J Biol Chem. 2003 Dec 19;278(51):51044-52. Epub 2003 Oct 2.


Regulation of TRPV5 single-channel activity by intracellular pH.

Cha SK, Jabbar W, Xie J, Huang CL.

J Membr Biol. 2007 Dec;220(1-3):79-85. Epub 2007 Nov 15.


Extracellular protons titrate voltage gating of a ligand-gated ion channel.

Martínez-François JR, Xu Y, Lu Z.

J Gen Physiol. 2010 Aug;136(2):179-87. doi: 10.1085/jgp.201010444. Epub 2010 Jul 12.


Outer pore topology of the ECaC-TRPV5 channel by cysteine scan mutagenesis.

Dodier Y, Banderali U, Klein H, Topalak O, Dafi O, Simoes M, Bernatchez G, Sauvé R, Parent L.

J Biol Chem. 2004 Feb 20;279(8):6853-62. Epub 2003 Nov 20.


A helix-breaking mutation in the epithelial Ca(2+) channel TRPV5 leads to reduced Ca(2+)-dependent inactivation.

Lee KP, Nair AV, Grimm C, van Zeeland F, Heller S, Bindels RJ, Hoenderop JG.

Cell Calcium. 2010 Nov;48(5):275-87. doi: 10.1016/j.ceca.2010.09.007. Epub 2010 Oct 29.


Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

Lambers TT, Weidema AF, Nilius B, Hoenderop JG, Bindels RJ.

J Biol Chem. 2004 Jul 9;279(28):28855-61. Epub 2004 Apr 30.


A gating mutation in the internal pore of ASIC1a.

Pfister Y, Gautschi I, Takeda AN, van Bemmelen M, Kellenberger S, Schild L.

J Biol Chem. 2006 Apr 28;281(17):11787-91. Epub 2006 Feb 23.


Separate gating mechanisms mediate the regulation of K2P potassium channel TASK-2 by intra- and extracellular pH.

Niemeyer MI, Cid LP, Peña-Münzenmayer G, Sepúlveda FV.

J Biol Chem. 2010 May 28;285(22):16467-75. doi: 10.1074/jbc.M110.107060. Epub 2010 Mar 29.


Functional architecture of the inner pore of a voltage-gated Ca2+ channel.

Zhen XG, Xie C, Fitzmaurice A, Schoonover CE, Orenstein ET, Yang J.

J Gen Physiol. 2005 Sep;126(3):193-204. Erratum in: J Gen Physiol. 2006 Jun;127(6):767.


Emerging issues of connexin channels: biophysics fills the gap.

Harris AL.

Q Rev Biophys. 2001 Aug;34(3):325-472. Review. Erratum in: Q Rev Biophys 2002 Feb;35(1):109.


Topology of the selectivity filter of a TRPV channel: rapid accessibility of contiguous residues from the external medium.

Dodier Y, Dionne F, Raybaud A, Sauvé R, Parent L.

Am J Physiol Cell Physiol. 2007 Dec;293(6):C1962-70. Epub 2007 Oct 17.


Extracellular pH dynamically controls cell surface delivery of functional TRPV5 channels.

Lambers TT, Oancea E, de Groot T, Topala CN, Hoenderop JG, Bindels RJ.

Mol Cell Biol. 2007 Feb;27(4):1486-94. Epub 2006 Dec 18.


A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues.

Cohen A, Ben-Abu Y, Hen S, Zilberberg N.

J Biol Chem. 2008 Jul 11;283(28):19448-55. doi: 10.1074/jbc.M801273200. Epub 2008 May 12.


Proton inhibition of unitary currents of vanilloid receptors.

Liu B, Yao J, Wang Y, Li H, Qin F.

J Gen Physiol. 2009 Sep;134(3):243-58. doi: 10.1085/jgp.200910255.


PIP2 activates TRPV5 and releases its inhibition by intracellular Mg2+.

Lee J, Cha SK, Sun TJ, Huang CL.

J Gen Physiol. 2005 Nov;126(5):439-51. Epub 2005 Oct 17.


K(+)-dependent gating of K(ir)1.1 channels is linked to pH gating through a conformational change in the pore.

Schulte U, Weidemann S, Ludwig J, Ruppersberg J, Fakler B.

J Physiol. 2001 Jul 1;534(Pt 1):49-58.


80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5).

Gkika D, Mahieu F, Nilius B, Hoenderop JG, Bindels RJ.

J Biol Chem. 2004 Jun 18;279(25):26351-7. Epub 2004 Apr 20.

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