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Items: 1 to 20 of 216

1.

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.

Jang MK, Mochizuki K, Zhou M, Jeong HS, Brady JN, Ozato K.

Mol Cell. 2005 Aug 19;19(4):523-34.

2.

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4.

Yang Z, Yik JH, Chen R, He N, Jang MK, Ozato K, Zhou Q.

Mol Cell. 2005 Aug 19;19(4):535-45.

3.

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

Zhou M, Huang K, Jung KJ, Cho WK, Klase Z, Kashanchi F, Pise-Masison CA, Brady JN.

J Virol. 2009 Jan;83(2):1036-44. doi: 10.1128/JVI.01316-08. Epub 2008 Oct 29.

4.

Positive transcription elongation factor b (P-TEFb) contributes to dengue virus-stimulated induction of interleukin-8 (IL-8).

Li LL, Hu ST, Wang SH, Lee HH, Wang YT, Ping YH.

Cell Microbiol. 2010 Nov;12(11):1589-603. doi: 10.1111/j.1462-5822.2010.01493.x.

PMID:
20618343
5.

The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase.

Mochizuki K, Nishiyama A, Jang MK, Dey A, Ghosh A, Tamura T, Natsume H, Yao H, Ozato K.

J Biol Chem. 2008 Apr 4;283(14):9040-8. doi: 10.1074/jbc.M707603200. Epub 2008 Jan 27.

7.

BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genes.

Patel MC, Debrosse M, Smith M, Dey A, Huynh W, Sarai N, Heightman TD, Tamura T, Ozato K.

Mol Cell Biol. 2013 Jun;33(12):2497-507. doi: 10.1128/MCB.01180-12. Epub 2013 Apr 15.

8.

G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb).

Qi T, Tang W, Wang L, Zhai L, Guo L, Zeng X.

J Biol Chem. 2011 Apr 29;286(17):15171-81. doi: 10.1074/jbc.M110.184374. Epub 2011 Mar 4.

9.

Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.

Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M.

J Biol Chem. 2012 Jan 6;287(2):1090-9. doi: 10.1074/jbc.M111.282855. Epub 2011 Nov 14.

10.

Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.

Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A.

J Virol. 2004 Dec;78(24):13522-33.

11.

Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation.

Itzen F, Greifenberg AK, Bösken CA, Geyer M.

Nucleic Acids Res. 2014 Jul;42(12):7577-90. doi: 10.1093/nar/gku449. Epub 2014 May 23.

12.

P-TEFb is a crucial co-factor for Myc transactivation.

Gargano B, Amente S, Majello B, Lania L.

Cell Cycle. 2007 Aug 15;6(16):2031-7. Epub 2007 Jun 5.

PMID:
17700062
13.
14.

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.

Wada T, Takagi T, Yamaguchi Y, Watanabe D, Handa H.

EMBO J. 1998 Dec 15;17(24):7395-403.

15.
16.

Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.

Mbonye UR, Gokulrangan G, Datt M, Dobrowolski C, Cooper M, Chance MR, Karn J.

PLoS Pathog. 2013;9(5):e1003338. doi: 10.1371/journal.ppat.1003338. Epub 2013 May 2.

17.

Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription.

Sabò A, Lusic M, Cereseto A, Giacca M.

Mol Cell Biol. 2008 Apr;28(7):2201-12. doi: 10.1128/MCB.01557-07. Epub 2008 Feb 4.

18.

Transcriptional activity of positive transcription elongation factor b kinase in vivo requires the C-terminal domain of RNA polymerase II.

Napolitano G, Majello B, Licciardo P, Giordano A, Lania L.

Gene. 2000 Aug 22;254(1-2):139-45.

PMID:
10974544
19.

Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.

Bartholomeeusen K, Xiang Y, Fujinaga K, Peterlin BM.

J Biol Chem. 2012 Oct 19;287(43):36609-16. doi: 10.1074/jbc.M112.410746. Epub 2012 Sep 5. Erratum in: J Biol Chem. 2013 Apr 26;288(17):12214.

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