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Items: 1 to 20 of 106

1.

Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin.

Jayaraman S, Eswaramoorthy S, Kumaran D, Swaminathan S.

Proteins. 2005 Nov 1;61(2):288-95.

PMID:
16104015
4.

Sequence homology and structural analysis of the clostridial neurotoxins.

Lacy DB, Stevens RC.

J Mol Biol. 1999 Sep 3;291(5):1091-104.

PMID:
10518945
5.

Structural analysis of the catalytic domain of tetanus neurotoxin.

Rao KN, Kumaran D, Binz T, Swaminathan S.

Toxicon. 2005 Jun 1;45(7):929-39. Epub 2005 Apr 13.

PMID:
15904688
6.

Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.

Swaminathan S, Eswaramoorthy S.

Nat Struct Biol. 2000 Aug;7(8):693-9.

PMID:
10932256
7.

Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.

Chen S, Hall C, Barbieri JT.

J Biol Chem. 2008 Jul 25;283(30):21153-9. doi: 10.1074/jbc.M800611200. Epub 2008 May 29.

8.

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.

Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.

Toxicon. 2013 Dec 1;75:108-21. doi: 10.1016/j.toxicon.2013.06.010. Epub 2013 Jun 29.

PMID:
23817019
9.

Unique ganglioside recognition strategies for clostridial neurotoxins.

Benson MA, Fu Z, Kim JJ, Baldwin MR.

J Biol Chem. 2011 Sep 30;286(39):34015-22. doi: 10.1074/jbc.M111.272054. Epub 2011 Aug 17.

10.

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.

Fotinou C, Emsley P, Black I, Ando H, Ishida H, Kiso M, Sinha KA, Fairweather NF, Isaacs NW.

J Biol Chem. 2001 Aug 24;276(34):32274-81. Epub 2001 Jun 19.

11.

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.

Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.

Biochem J. 2010 Oct 15;431(2):207-16. doi: 10.1042/BJ20101042.

PMID:
20704566
12.

Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity.

Rossetto O, Caccin P, Rigoni M, Tonello F, Bortoletto N, Stevens RC, Montecucco C.

Toxicon. 2001 Aug;39(8):1151-9.

PMID:
11306125
13.

Molecular structures and functional relationships in clostridial neurotoxins.

Swaminathan S.

FEBS J. 2011 Dec;278(23):4467-85. doi: 10.1111/j.1742-4658.2011.08183.x. Epub 2011 Jun 13. Review.

14.

Crystallographic evidence for doxorubicin binding to the receptor-binding site in Clostridium botulinum neurotoxin B.

Eswaramoorthy S, Kumaran D, Swaminathan S.

Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1743-6. Epub 2001 Oct 25.

PMID:
11679763
15.

Site-directed mutagenesis identifies active-site residues of the light chain of botulinum neurotoxin type A.

Rigoni M, Caccin P, Johnson EA, Montecucco C, Rossetto O.

Biochem Biophys Res Commun. 2001 Nov 16;288(5):1231-7.

PMID:
11700044
16.

Structural and mutational analyses of the receptor binding domain of botulinum D/C mosaic neurotoxin: insight into the ganglioside binding mechanism.

Nuemket N, Tanaka Y, Tsukamoto K, Tsuji T, Nakamura K, Kozaki S, Yao M, Tanaka I.

Biochem Biophys Res Commun. 2011 Jul 29;411(2):433-9. doi: 10.1016/j.bbrc.2011.06.173. Epub 2011 Jul 2.

PMID:
21749855
17.

The use of microcalorimetry to characterize tetanus neurotoxin, pertussis toxin and filamentous haemagglutinin.

Krell T, Greco F, Nicolaï MC, Dubayle J, Renauld-Mongénie G, Poisson N, Bernard I.

Biotechnol Appl Biochem. 2003 Dec;38(Pt 3):241-51.

PMID:
12911336
18.

Identification of novel small molecules that bind to two different sites on the surface of tetanus toxin C fragment.

Cosman M, Lightstone FC, Krishnan VV, Zeller L, Prieto MC, Roe DC, Balhorn R.

Chem Res Toxicol. 2002 Oct;15(10):1218-28.

PMID:
12387617
19.

Location of the synaptosome-binding regions on botulinum neurotoxin B.

Dolimbek BZ, Steward LE, Aoki KR, Atassi MZ.

Biochemistry. 2012 Jan 10;51(1):316-28. doi: 10.1021/bi201322c. Epub 2011 Dec 29.

PMID:
22146011
20.

Structure and function of tetanus and botulinum neurotoxins.

Montecucco C, Schiavo G.

Q Rev Biophys. 1995 Nov;28(4):423-72. Review.

PMID:
8771234

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