Similar articles for PMID: 16098467

Year	Number of Results
1948	1
1962	1
1977	1
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1998	1
2000	3
2001	3
2002	2
2003	8
2004	9
2005	8
2006	7
2007	12
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2009	3
2010	4
2011	13
2012	5
2013	6
2014	5
2015	4
2016	9
2017	5
2018	4
2019	9
2020	7
2021	3
2022	11
2023	4
2024	0

1

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.

Isaacs JS, Jung YJ, Mole DR, Lee S, Torres-Cabala C, Chung YL, Merino M, Trepel J, Zbar B, Toro J, Ratcliffe PJ, Linehan WM, Neckers L. Isaacs JS, et al. Cancer Cell. 2005 Aug;8(2):143-53. doi: 10.1016/j.ccr.2005.06.017. Cancer Cell. 2005. PMID: 16098467 Free article.

2

Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors.

Ooi A, Furge KA. Ooi A, et al. Chin J Cancer. 2012 Sep;31(9):413-20. doi: 10.5732/cjc.012.10102. Epub 2012 Jul 2. Chin J Cancer. 2012. PMID: 22776233 Free PMC article. Review.

3

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU. Wiesener MS, et al. Cancer Res. 2001 Jul 1;61(13):5215-22. Cancer Res. 2001. PMID: 11431362

4

Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.

Yogev O, Yogev O, Singer E, Shaulian E, Goldberg M, Fox TD, Pines O. Yogev O, et al. PLoS Biol. 2010 Mar 9;8(3):e1000328. doi: 10.1371/journal.pbio.1000328. PLoS Biol. 2010. PMID: 20231875 Free PMC article.

5

Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.

Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH. Krieg M, et al. Oncogene. 2000 Nov 16;19(48):5435-43. doi: 10.1038/sj.onc.1203938. Oncogene. 2000. PMID: 11114720

6

Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion.

Sudarshan S, Shanmugasundaram K, Naylor SL, Lin S, Livi CB, O'Neill CF, Parekh DJ, Yeh IT, Sun LZ, Block K. Sudarshan S, et al. PLoS One. 2011;6(6):e21037. doi: 10.1371/journal.pone.0021037. Epub 2011 Jun 14. PLoS One. 2011. PMID: 21695080 Free PMC article.

7

Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.

Ashrafian H, O'Flaherty L, Adam J, Steeples V, Chung YL, East P, Vanharanta S, Lehtonen H, Nye E, Hatipoglu E, Miranda M, Howarth K, Shukla D, Troy H, Griffiths J, Spencer-Dene B, Yusuf M, Volpi E, Maxwell PH, Stamp G, Poulsom R, Pugh CW, Costa B, Bardella C, Di Renzo MF, Kotlikoff MI, Launonen V, Aaltonen L, El-Bahrawy M, Tomlinson I, Pollard PJ. Ashrafian H, et al. Cancer Res. 2010 Nov 15;70(22):9153-65. doi: 10.1158/0008-5472.CAN-10-1949. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978192

8

Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.

Blancher C, Moore JW, Robertson N, Harris AL. Blancher C, et al. Cancer Res. 2001 Oct 1;61(19):7349-55. Cancer Res. 2001. PMID: 11585776

9

Fumarate hydratase deficiency and cancer: activation of hypoxia signaling?

Ratcliffe PJ. Ratcliffe PJ. Cancer Cell. 2007 Apr;11(4):303-5. doi: 10.1016/j.ccr.2007.03.015. Cancer Cell. 2007. PMID: 17418405 Free article.

10

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer.

Yang Y, Valera VA, Padilla-Nash HM, Sourbier C, Vocke CD, Vira MA, Abu-Asab MS, Bratslavsky G, Tsokos M, Merino MJ, Pinto PA, Srinivasan R, Ried T, Neckers L, Linehan WM. Yang Y, et al. Cancer Genet Cytogenet. 2010 Jan 1;196(1):45-55. doi: 10.1016/j.cancergencyto.2009.08.018. Cancer Genet Cytogenet. 2010. PMID: 19963135 Free PMC article.

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