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Items: 1 to 20 of 279

1.
2.

Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.

Cheng S, Afif H, Martel-Pelletier J, Pelletier JP, Li X, Farrajota K, Lavigne M, Fahmi H.

J Biol Chem. 2004 May 21;279(21):22057-65. Epub 2004 Mar 15.

4.

Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.

Yucel-Lindberg T, Olsson T, Kawakami T.

Cell Signal. 2006 Dec;18(12):2131-42.

PMID:
16766159
5.

Valproic acid suppresses interleukin-1ß-induced microsomal prostaglandin E2 synthase-1 expression in chondrocytes through upregulation of NAB1.

Zayed N, El Mansouri FE, Chabane N, Kapoor M, Martel-Pelletier J, Benderdour M, Pelletier JP, Duval N, Fahmi H.

J Rheumatol. 2011 Mar;38(3):492-502. doi: 10.3899/jrheum.100907. Epub 2011 Jan 15.

PMID:
21239760
7.

Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways.

Masuko-Hongo K, Berenbaum F, Humbert L, Salvat C, Goldring MB, Thirion S.

Arthritis Rheum. 2004 Sep;50(9):2829-38.

8.

Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages.

Díaz-Muñoz MD, Osma-García IC, Cacheiro-Llaguno C, Fresno M, Iñiguez MA.

Cell Signal. 2010 Oct;22(10):1427-36. doi: 10.1016/j.cellsig.2010.05.011. Epub 2010 May 21.

PMID:
20546888
9.

Revealing the effect of 6-gingerol, 6-shogaol and curcumin on mPGES-1, GSK-3β and β-catenin pathway in A549 cell line.

Eren D, Betul YM.

Chem Biol Interact. 2016 Oct 25;258:257-65. doi: 10.1016/j.cbi.2016.09.012. Epub 2016 Sep 16.

PMID:
27645308
10.
11.

Induction of human microsomal prostaglandin E synthase 1 by activated oncogene RhoA GTPase in A549 human epithelial cancer cells.

Choi HJ, Lee DH, Park SH, Kim J, Do KH, An TJ, Ahn YS, Park CB, Moon Y.

Biochem Biophys Res Commun. 2011 Sep 30;413(3):448-53. doi: 10.1016/j.bbrc.2011.08.116. Epub 2011 Aug 30.

PMID:
21907186
12.

Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.

Mbalaviele G, Pauley AM, Shaffer AF, Zweifel BS, Mathialagan S, Mnich SJ, Nemirovskiy OV, Carter J, Gierse JK, Wang JL, Vazquez ML, Moore WM, Masferrer JL.

Biochem Pharmacol. 2010 May 15;79(10):1445-54. doi: 10.1016/j.bcp.2010.01.003. Epub 2010 Jan 11.

PMID:
20067770
13.

Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.

Terzuoli E, Donnini S, Giachetti A, Iñiguez MA, Fresno M, Melillo G, Ziche M.

Clin Cancer Res. 2010 Aug 15;16(16):4207-16. doi: 10.1158/1078-0432.CCR-10-0156. Epub 2010 Aug 3.

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Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.

Subbaramaiah K, Yoshimatsu K, Scherl E, Das KM, Glazier KD, Golijanin D, Soslow RA, Tanabe T, Naraba H, Dannenberg AJ.

J Biol Chem. 2004 Mar 26;279(13):12647-58. Epub 2004 Jan 13.

16.

Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.

Jüngel A, Distler O, Schulze-Horsel U, Huber LC, Ha HR, Simmen B, Kalden JR, Pisetsky DS, Gay S, Distler JH.

Arthritis Rheum. 2007 Nov;56(11):3564-74.

17.

c-Jun N-terminal kinase-mediated stabilization of microsomal prostaglandin E2 synthase-1 mRNA regulates delayed microsomal prostaglandin E2 synthase-1 expression and prostaglandin E2 biosynthesis by cardiomyocytes.

Degousee N, Angoulvant D, Fazel S, Stefanski E, Saha S, Iliescu K, Lindsay TF, Fish JE, Marsden PA, Li RK, Audoly LP, Jakobsson PJ, Rubin BB.

J Biol Chem. 2006 Jun 16;281(24):16443-52. Epub 2006 Apr 19.

18.

Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: possible involvement of NF-κB and p38 MAPK inhibition.

Olajide OA, Bhatia HS, de Oliveira AC, Wright CW, Fiebich BL.

Eur J Med Chem. 2013 May;63:333-9. doi: 10.1016/j.ejmech.2013.02.004. Epub 2013 Feb 19.

PMID:
23507189
19.

Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.

Koeberle A, Northoff H, Werz O.

Mol Cancer Ther. 2009 Aug;8(8):2348-55. doi: 10.1158/1535-7163.MCT-09-0290. Epub 2009 Aug 11.

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