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Items: 1 to 20 of 87

1.

IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression.

Brand S, Beigel F, Olszak T, Zitzmann K, Eichhorst ST, Otte JM, Diebold J, Diepolder H, Adler B, Auernhammer CJ, Göke B, Dambacher J.

Am J Physiol Gastrointest Liver Physiol. 2005 Nov;289(5):G960-8. Epub 2005 Jul 28.

2.

SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29.

Brand S, Zitzmann K, Dambacher J, Beigel F, Olszak T, Vlotides G, Eichhorst ST, Göke B, Diepolder H, Auernhammer CJ.

Biochem Biophys Res Commun. 2005 Jun 3;331(2):543-8.

PMID:
15850793
3.

Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.

Dambacher J, Beigel F, Seiderer J, Haller D, Göke B, Auernhammer CJ, Brand S.

Gut. 2007 Sep;56(9):1257-65. Epub 2007 Apr 20.

4.

Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells.

Zitzmann K, Brand S, Baehs S, Göke B, Meinecke J, Spöttl G, Meyer H, Auernhammer CJ.

Biochem Biophys Res Commun. 2006 Jun 16;344(4):1334-41. Epub 2006 Apr 24.

PMID:
16650825
5.

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.

Diegelmann J, Beigel F, Zitzmann K, Kaul A, Göke B, Auernhammer CJ, Bartenschlager R, Diepolder HM, Brand S.

PLoS One. 2010 Dec 8;5(12):e15200. doi: 10.1371/journal.pone.0015200.

6.

Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling.

Dumoutier L, Tounsi A, Michiels T, Sommereyns C, Kotenko SV, Renauld JC.

J Biol Chem. 2004 Jul 30;279(31):32269-74. Epub 2004 May 27.

7.

The role of the novel Th17 cytokine IL-26 in intestinal inflammation.

Dambacher J, Beigel F, Zitzmann K, De Toni EN, Göke B, Diepolder HM, Auernhammer CJ, Brand S.

Gut. 2009 Sep;58(9):1207-17. doi: 10.1136/gut.2007.130112. Epub 2008 May 15.

PMID:
18483078
8.

Expression of interferon alfa signaling components in human alcoholic liver disease.

Nguyen VA, Gao B.

Hepatology. 2002 Feb;35(2):425-32.

PMID:
11826419
9.

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.

Brand S, Beigel F, Olszak T, Zitzmann K, Eichhorst ST, Otte JM, Diepolder H, Marquardt A, Jagla W, Popp A, Leclair S, Herrmann K, Seiderer J, Ochsenkühn T, Göke B, Auernhammer CJ, Dambacher J.

Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G827-38.

10.

Potential anti-tumor effect of IFN-λ2 (IL-28A) against human lung cancer cells.

Tezuka Y, Endo S, Matsui A, Sato A, Saito K, Semba K, Takahashi M, Murakami T.

Lung Cancer. 2012 Dec;78(3):185-92. doi: 10.1016/j.lungcan.2012.09.005. Epub 2012 Sep 27.

PMID:
23021208
11.
12.

Production, characterization, and applications of two novel monoclonal antibodies against human interleukin-28A.

Li M, Chen Y, Huang T, Liu Y, He S.

Tissue Antigens. 2006 Dec;68(6):477-82.

PMID:
17176437
13.

Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.

Nagalakshmi ML, Rascle A, Zurawski S, Menon S, de Waal Malefyt R.

Int Immunopharmacol. 2004 May;4(5):679-91.

PMID:
15120652
14.

IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet.

Siebler J, Wirtz S, Weigmann B, Atreya I, Schmitt E, Kreft A, Galle PR, Neurath MF.

Gastroenterology. 2007 Jan;132(1):358-71. Epub 2006 Oct 21.

PMID:
17241885
15.

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus.

Baldridge MT, Lee S, Brown JJ, McAllister N, Urbanek K, Dermody TS, Nice TJ, Virgin HW.

J Virol. 2017 Mar 13;91(7). pii: e02079-16. doi: 10.1128/JVI.02079-16. Print 2017 Apr 1.

16.

The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.

Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H.

J Leukoc Biol. 2004 Aug;76(2):314-21. Epub 2004 May 3. Review.

PMID:
15123776
17.

EPSTI1 Is Involved in IL-28A-Mediated Inhibition of HCV Infection.

Meng X, Yang D, Yu R, Zhu H.

Mediators Inflamm. 2015;2015:716315. doi: 10.1155/2015/716315. Epub 2015 Jun 3.

18.

Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells.

Brand S, Olszak T, Beigel F, Diebold J, Otte JM, Eichhorst ST, Göke B, Dambacher J.

J Cell Biochem. 2006 Mar 1;97(4):709-23.

PMID:
16215992
19.

Interferon-lambdas: the modulators of antivirus, antitumor, and immune responses.

Li M, Liu X, Zhou Y, Su SB.

J Leukoc Biol. 2009 Jul;86(1):23-32. doi: 10.1189/jlb.1208761. Epub 2009 Apr 30. Review.

PMID:
19304895
20.

IL-10 protects mouse intestinal epithelial cells from Fas-induced apoptosis via modulating Fas expression and altering caspase-8 and FLIP expression.

Bharhani MS, Borojevic R, Basak S, Ho E, Zhou P, Croitoru K.

Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G820-9.

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