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Items: 1 to 20 of 113

1.

Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes.

Marín YE, Namkoong J, Shin SS, Raines J, Degenhardt K, White E, Chen S.

Neuropharmacology. 2005;49 Suppl 1:70-9.

PMID:
16040064
2.

Involvement of metabotropic glutamate receptor 1, a G protein coupled receptor, in melanoma development.

Marín YE, Chen S.

J Mol Med (Berl). 2004 Nov;82(11):735-49. Epub 2004 Aug 21. Review.

PMID:
15322701
3.

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

Pollock PM, Cohen-Solal K, Sood R, Namkoong J, Martino JJ, Koganti A, Zhu H, Robbins C, Makalowska I, Shin SS, Marin Y, Roberts KG, Yudt LM, Chen A, Cheng J, Incao A, Pinkett HW, Graham CL, Dunn K, Crespo-Carbone SM, Mackason KR, Ryan KB, Sinsimer D, Goydos J, Reuhl KR, Eckhaus M, Meltzer PS, Pavan WJ, Trent JM, Chen S.

Nat Genet. 2003 May;34(1):108-12.

PMID:
12704387
4.

Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates ERK1/2 via PKCepsilon.

Marín YE, Namkoong J, Cohen-Solal K, Shin SS, Martino JJ, Oka M, Chen S.

Cell Signal. 2006 Aug;18(8):1279-86. Epub 2005 Nov 21.

PMID:
16305822
5.

Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation.

Shin SS, Namkoong J, Wall BA, Gleason R, Lee HJ, Chen S.

Pigment Cell Melanoma Res. 2008 Jun;21(3):368-78. doi: 10.1111/j.1755-148X.2008.00452.x. Epub 2008 Apr 23.

6.

Functional effects of GRM1 suppression in human melanoma cells.

Wangari-Talbot J, Wall BA, Goydos JS, Chen S.

Mol Cancer Res. 2012 Nov;10(11):1440-50. doi: 10.1158/1541-7786.MCR-12-0158. Epub 2012 Jul 13.

7.

Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma.

Namkoong J, Shin SS, Lee HJ, Marín YE, Wall BA, Goydos JS, Chen S.

Cancer Res. 2007 Mar 1;67(5):2298-305.

8.

Glutamatergic signaling in cellular transformation.

Teh JL, Chen S.

Pigment Cell Melanoma Res. 2012 May;25(3):331-42. doi: 10.1111/j.1755-148X.2012.00983.x. Epub 2012 Feb 20. Review.

PMID:
22273393
9.

Tg(Grm1) transgenic mice: a murine model that mimics spontaneous uveal melanoma in humans?

Schiffner S, Braunger BM, de Jel MM, Coupland SE, Tamm ER, Bosserhoff AK.

Exp Eye Res. 2014 Oct;127:59-68. doi: 10.1016/j.exer.2014.07.009. Epub 2014 Jul 19.

PMID:
25051141
10.

Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma.

Ohtani Y, Harada T, Funasaka Y, Nakao K, Takahara C, Abdel-Daim M, Sakai N, Saito N, Nishigori C, Aiba A.

Oncogene. 2008 Dec 4;27(57):7162-70. doi: 10.1038/onc.2008.329. Epub 2008 Sep 8.

PMID:
18776920
11.

Regulation of mGluR1 expression in human melanocytes and melanoma cells.

Lee HJ, Wall BA, Wangari-Talbot J, Chen S.

Biochim Biophys Acta. 2012 Nov-Dec;1819(11-12):1123-31. doi: 10.1016/j.bbagrm.2012.06.005. Epub 2012 Jul 5.

12.

AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).

Shin SS, Wall BA, Goydos JS, Chen S.

Pigment Cell Melanoma Res. 2010 Feb;23(1):103-11. doi: 10.1111/j.1755-148X.2009.00648.x. Epub 2009 Oct 20.

13.

Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor.

Teh JL, Shah R, Shin SS, Wen Y, Mehnert JM, Goydos J, Chen S.

Pigment Cell Melanoma Res. 2014 Jul;27(4):621-9. doi: 10.1111/pcmr.12237. Epub 2014 Apr 11.

14.

SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis.

Cronin JC, Watkins-Chow DE, Incao A, Hasskamp JH, Schönewolf N, Aoude LG, Hayward NK, Bastian BC, Dummer R, Loftus SK, Pavan WJ.

Cancer Res. 2013 Sep 15;73(18):5709-18. doi: 10.1158/0008-5472.CAN-12-4620. Epub 2013 Aug 1.

15.

Highly pigmented Tg(Grm1) mouse melanoma develops non-pigmented melanoma cells in distant metastases.

Schiffner S, Chen S, Becker JC, Bosserhoff AK.

Exp Dermatol. 2012 Oct;21(10):786-8. doi: 10.1111/j.1600-0625.2012.01560.x. Epub 2012 Aug 7.

PMID:
22882420
16.

Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.

Martino JJ, Wall BA, Mastrantoni E, Wilimczyk BJ, La Cava SN, Degenhardt K, White E, Chen S.

Oncogene. 2013 Sep 12;32(37):4366-76. doi: 10.1038/onc.2012.471. Epub 2012 Oct 22.

17.

Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells.

Wall BA, Wangari-Talbot J, Shin SS, Schiff D, Sierra J, Yu LJ, Khan A, Haffty B, Goydos JS, Chen S.

Pigment Cell Melanoma Res. 2014 Mar;27(2):263-74. doi: 10.1111/pcmr.12207. Epub 2014 Jan 22.

18.

Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.

Teh JL, Shah R, La Cava S, Dolfi SC, Mehta MS, Kongara S, Price S, Ganesan S, Reuhl KR, Hirshfield KM, Karantza V, Chen S.

Breast Cancer Res Treat. 2015 May;151(1):57-73. doi: 10.1007/s10549-015-3365-8. Epub 2015 Apr 10.

19.

Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.

Wen Y, Li J, Koo J, Shin SS, Lin Y, Jeong BS, Mehnert JM, Chen S, Cohen-Sola KA, Goydos JS.

Cancer Res. 2014 May 1;74(9):2499-509. doi: 10.1158/0008-5472.CAN-13-1531. Epub 2014 Feb 3.

20.

NDRG2 gene expression in B16F10 melanoma cells restrains melanogenesis via inhibition of Mitf expression.

Kim A, Yang Y, Lee MS, Yoo YD, Lee HG, Lim JS.

Pigment Cell Melanoma Res. 2008 Dec;21(6):653-64. doi: 10.1111/j.1755-148X.2008.00503.x.

PMID:
19067970

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