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Items: 1 to 20 of 114

1.
2.

Activation of Proalpha2(I) collagen promoter during hepatic fibrogenesis in transgenic mice.

Inagaki Y, Truter S, Bou-Gharios G, Garrett LA, de Crombrugghe B, Nemoto T, Greenwel P.

Biochem Biophys Res Commun. 1998 Sep 29;250(3):606-11.

PMID:
9784393
3.

Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice.

Inagaki Y, Kushida M, Higashi K, Itoh J, Higashiyama R, Hong YY, Kawada N, Namikawa K, Kiyama H, Bou-Gharios G, Watanabe T, Okazaki I, Ikeda K.

Gastroenterology. 2005 Jul;129(1):259-68.

PMID:
16012952
4.
5.

The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo.

Hellerbrand C, Stefanovic B, Giordano F, Burchardt ER, Brenner DA.

J Hepatol. 1999 Jan;30(1):77-87.

PMID:
9927153
6.

Negligible contribution of bone marrow-derived cells to collagen production during hepatic fibrogenesis in mice.

Higashiyama R, Moro T, Nakao S, Mikami K, Fukumitsu H, Ueda Y, Ikeda K, Adachi E, Bou-Gharios G, Okazaki I, Inagaki Y.

Gastroenterology. 2009 Oct;137(4):1459-66.e1. doi: 10.1053/j.gastro.2009.07.006. Epub 2009 Jul 29.

PMID:
19596008
7.

The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression.

Chen SJ, Ning H, Ishida W, Sodin-Semrl S, Takagawa S, Mori Y, Varga J.

J Biol Chem. 2006 Jul 28;281(30):21183-97. Epub 2006 May 15.

8.

Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.

Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B.

J Biol Chem. 2003 Jul 4;278(27):25109-19. Epub 2003 Apr 21.

9.

Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha.

Urtasun R, Cubero FJ, Vera M, Nieto N.

Gastroenterology. 2009 Apr;136(4):1410-22, e1-4. doi: 10.1053/j.gastro.2008.12.065. Epub 2009 Jan 6.

PMID:
19250650
10.

Osteoblast-specific expression of the alpha 2(I) collagen promoter in transgenic mice: correlation with the distribution of TGF-beta 1.

D'Souza RN, Niederreither K, de Crombrugghe B.

J Bone Miner Res. 1993 Sep;8(9):1127-36.

PMID:
8237483
11.

Glycyrrhizin and its metabolite inhibit Smad3-mediated type I collagen gene transcription and suppress experimental murine liver fibrosis.

Moro T, Shimoyama Y, Kushida M, Hong YY, Nakao S, Higashiyama R, Sugioka Y, Inoue H, Okazaki I, Inagaki Y.

Life Sci. 2008 Oct 10;83(15-16):531-9. doi: 10.1016/j.lfs.2008.07.023. Epub 2008 Aug 16.

PMID:
18771671
12.

Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.

Akool el-S, Doller A, Müller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W.

J Biol Chem. 2005 Nov 25;280(47):39403-16. Epub 2005 Sep 23.

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DNase I-hypersensitive sites enhance alpha1(I) collagen gene expression in hepatic stellate cells.

Yata Y, Scanga A, Gillan A, Yang L, Reif S, Breindl M, Brenner DA, Rippe RA.

Hepatology. 2003 Feb;37(2):267-76.

PMID:
12540776
16.

Regulation of the alpha 2(I) collagen gene transcription in fat-storing cells derived from a cirrhotic liver.

Inagaki Y, Truter S, Greenwel P, Rojkind M, Unoura M, Kobayashi K, Ramirez F.

Hepatology. 1995 Aug;22(2):573-9.

PMID:
7635427
17.

Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice.

Czochra P, Klopcic B, Meyer E, Herkel J, Garcia-Lazaro JF, Thieringer F, Schirmacher P, Biesterfeld S, Galle PR, Lohse AW, Kanzler S.

J Hepatol. 2006 Sep;45(3):419-28. Epub 2006 May 30.

PMID:
16842882
18.

Transgenic mice with a mutated collagen promoter display normal response during bleomycin-induced fibrosis and possess neurological abnormalities.

Stoddart JH Jr, Ladd D, Bronson RT, Harmon M, Jaworski J, Pritzker C, Lausen N, Smith BD.

J Cell Biochem. 2000 Feb;77(1):135-48.

PMID:
10679824
19.

Activation by acetaldehyde of the promoter of the mouse alpha2(I) collagen gene when transfected into rat activated stellate cells.

Anania FA, Potter JJ, Rennie-Tankersley L, Mezey E.

Arch Biochem Biophys. 1996 Jul 15;331(2):187-93.

PMID:
8660697
20.

Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.

Zion O, Genin O, Kawada N, Yoshizato K, Roffe S, Nagler A, Iovanna JL, Halevy O, Pines M.

Pancreas. 2009 May;38(4):427-35. doi: 10.1097/MPA.0b013e3181967670.

PMID:
19188864

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