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Items: 1 to 20 of 113

1.
2.

Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle.

Watanabe N, Broome M, Hunter T.

EMBO J. 1995 May 1;14(9):1878-91.

3.
4.

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.

Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.

Nat Med. 2002 Oct;8(10):1145-52. Epub 2002 Sep 16.

PMID:
12244301
5.
7.

NFBD1/MDC1 is phosphorylated by PLK1 and controls G2/M transition through the regulation of a TOPOIIα-mediated decatenation checkpoint.

Ando K, Ozaki T, Hirota T, Nakagawara A.

PLoS One. 2013 Dec 11;8(12):e82744. doi: 10.1371/journal.pone.0082744. eCollection 2013.

8.

UCN-01 abrogates G2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee1Hu kinase and activation of the Cdc25C phosphatase.

Yu L, Orlandi L, Wang P, Orr MS, Senderowicz AM, Sausville EA, Silvestrini R, Watanabe N, Piwnica-Worms H, O'Connor PM.

J Biol Chem. 1998 Dec 11;273(50):33455-64.

9.

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.

Fujita N, Sato S, Katayama K, Tsuruo T.

J Biol Chem. 2002 Aug 9;277(32):28706-13. Epub 2002 May 31.

10.

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.

Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D, Vinci F, Chiappetta G, Tsichlis P, Bellacosa A, Fusco A, Santoro M.

Nat Med. 2002 Oct;8(10):1136-44. Epub 2002 Sep 16.

PMID:
12244303
11.

ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.

Lenferink AE, Busse D, Flanagan WM, Yakes FM, Arteaga CL.

Cancer Res. 2001 Sep 1;61(17):6583-91.

12.

DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.

An J, Huang YC, Xu QZ, Zhou LJ, Shang ZF, Huang B, Wang Y, Liu XD, Wu DC, Zhou PK.

BMC Mol Biol. 2010 Mar 6;11:18. doi: 10.1186/1471-2199-11-18.

13.

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.

Liang J, Zubovitz J, Petrocelli T, Kotchetkov R, Connor MK, Han K, Lee JH, Ciarallo S, Catzavelos C, Beniston R, Franssen E, Slingerland JM.

Nat Med. 2002 Oct;8(10):1153-60. Epub 2002 Sep 16.

PMID:
12244302
14.
15.

Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.

Chang KL, Kung ML, Chow NH, Su SJ.

Biochem Pharmacol. 2004 Feb 15;67(4):717-26.

PMID:
14757171
16.

Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.

Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, Tokumara S, Yahata Y, Tohyama M, Hashimoto K.

J Invest Dermatol. 2004 Jun;122(6):1356-64.

17.
18.

Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression.

Liu YL, Zhang GQ, Yang Y, Zhang CY, Fu RX, Yang YM.

Nutr Cancer. 2013;65(7):1034-41. doi: 10.1080/01635581.2013.810290. Epub 2013 Sep 20.

PMID:
24053672
19.

Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.

Potapova TA, Sivakumar S, Flynn JN, Li R, Gorbsky GJ.

Mol Biol Cell. 2011 Apr 15;22(8):1191-206. doi: 10.1091/mbc.E10-07-0599. Epub 2011 Feb 16.

20.

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1).

Sekimoto T, Fukumoto M, Yoneda Y.

EMBO J. 2004 May 5;23(9):1934-42. Epub 2004 Apr 1.

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