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Items: 1 to 20 of 78

1.

Cooperative activation of transcription by autoimmune regulator AIRE and CBP.

Pitkänen J, Rebane A, Rowell J, Murumägi A, Ströbel P, Möll K, Saare M, Heikkilä J, Doucas V, Marx A, Peterson P.

Biochem Biophys Res Commun. 2005 Aug 5;333(3):944-53.

PMID:
15964547
2.

Functional interaction of AIRE with PIAS1 in transcriptional regulation.

Ilmarinen T, Kangas H, Kytömaa T, Eskelin P, Saharinen J, Seeler JS, Tanhuanpää K, Chan FY, Slattery RM, Alakurtti K, Palvimo JJ, Ulmanen I.

Mol Immunol. 2008 Apr;45(7):1847-62.

PMID:
18083234
3.

Autoimmune regulator is acetylated by transcription coactivator CBP/p300.

Saare M, Rebane A, Rajashekar B, Vilo J, Peterson P.

Exp Cell Res. 2012 Aug 15;318(14):1767-78. doi: 10.1016/j.yexcr.2012.04.013. Epub 2012 May 30.

PMID:
22659170
4.

Autoimmune regulator: from loss of function to autoimmunity.

Pitkänen J, Peterson P.

Genes Immun. 2003 Jan;4(1):12-21. Review.

PMID:
12595897
5.

AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix.

Tao Y, Kupfer R, Stewart BJ, Williams-Skipp C, Crowell CK, Patel DD, Sain S, Scheinman RI.

Mol Immunol. 2006 Feb;43(4):335-45. Epub 2005 Mar 23.

PMID:
16310047
6.

Ets transcription factors regulate AIRE gene promoter.

Murumägi A, Silvennoinen O, Peterson P.

Biochem Biophys Res Commun. 2006 Sep 22;348(2):768-74. Epub 2006 Jul 31.

PMID:
16890195
7.

Isolation and characterization of the mouse Aire gene.

Mittaz L, Rossier C, Heino M, Peterson P, Krohn KJ, Gos A, Morris MA, Kudoh J, Shimizu N, Antonarakis SE, Scott HS.

Biochem Biophys Res Commun. 1999 Feb 16;255(2):483-90.

PMID:
10049735
8.

Evaluation of the autoimmune regulator (AIRE) gene mutations in a cohort of Italian patients with autoimmune-polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) and in their relatives.

Cervato S, Mariniello B, Lazzarotto F, Morlin L, Zanchetta R, Radetti G, De Luca F, Valenzise M, Giordano R, Rizzo D, Giordano C, Betterle C.

Clin Endocrinol (Oxf). 2009 Mar;70(3):421-8. doi: 10.1111/j.1365-2265.2008.03318.x. Epub 2008 Jun 27.

PMID:
18616706
9.

AIRE-1 (autoimmune regulator type 1) as a regulator of the thymic induction of negative selection.

Park Y, Moon Y, Chung HY.

Ann N Y Acad Sci. 2003 Nov;1005:431-5.

PMID:
14679106
10.

Polymorphisms at +49A/G and CT60 sites in the 3' UTR of the CTLA-4 gene and APECED-related AIRE gene mutations analysis in sporadic idiopathic hypoparathyroidism.

Goswami R, Gupta N, Ray D, Rani R, Tomar N, Sarin R, Vupputuri MR.

Int J Immunogenet. 2005 Dec;32(6):393-400.

PMID:
16313305
11.

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

Heino M, Peterson P, Kudoh J, Nagamine K, Lagerstedt A, Ovod V, Ranki A, Rantala I, Nieminen M, Tuukkanen J, Scott HS, Antonarakis SE, Shimizu N, Krohn K.

Biochem Biophys Res Commun. 1999 Apr 21;257(3):821-5.

PMID:
10208866
12.

AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells.

Oven I, Brdicková N, Kohoutek J, Vaupotic T, Narat M, Peterlin BM.

Mol Cell Biol. 2007 Dec;27(24):8815-23. Epub 2007 Oct 15.

13.

Expression and alternative splicing of the mouse autoimmune regulator gene (Aire).

Ruan QG, Wang CY, Shi JD, She JX.

J Autoimmun. 1999 Nov;13(3):307-13.

PMID:
10550218
14.

Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage.

Sillanpää N, Magureanu CG, Murumägi A, Reinikainen A, West A, Manninen A, Lahti M, Ranki A, Saksela K, Krohn K, Lahesmaa R, Peterson P.

Mol Immunol. 2004 Nov;41(12):1185-98.

PMID:
15482854
15.

Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype.

Hubert FX, Kinkel SA, Crewther PE, Cannon PZ, Webster KE, Link M, Uibo R, O'Bryan MK, Meager A, Forehan SP, Smyth GK, Mittaz L, Antonarakis SE, Peterson P, Heath WR, Scott HS.

J Immunol. 2009 Mar 15;182(6):3902-18. doi: 10.4049/jimmunol.0802124.

16.

Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

Liston A, Gray DH, Lesage S, Fletcher AL, Wilson J, Webster KE, Scott HS, Boyd RL, Peltonen L, Goodnow CC.

J Exp Med. 2004 Oct 18;200(8):1015-26.

17.

Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients.

Pöntynen N, Miettinen A, Arstila TP, Kämpe O, Alimohammadi M, Vaarala O, Peltonen L, Ulmanen I.

J Autoimmun. 2006 Sep;27(2):96-104. Epub 2006 Jul 3.

PMID:
16820279
18.

Disruption of immunological tolerance: role of AIRE gene in autoimmunity.

Rizzi M, Ferrera F, Filaci G, Indiveri F.

Autoimmun Rev. 2006 Feb;5(2):145-7. Epub 2005 Sep 13. Review.

PMID:
16431348
19.

A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

Kekäläinen E, Tuovinen H, Joensuu J, Gylling M, Franssila R, Pöntynen N, Talvensaari K, Perheentupa J, Miettinen A, Arstila TP.

J Immunol. 2007 Jan 15;178(2):1208-15.

20.

The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function.

Ruan QG, Tung K, Eisenman D, Setiady Y, Eckenrode S, Yi B, Purohit S, Zheng WP, Zhang Y, Peltonen L, She JX.

J Immunol. 2007 Jun 1;178(11):7173-80.

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