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Items: 1 to 20 of 47

1.

A genetic screen for candidate tumor suppressors identifies REST.

Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ.

Cell. 2005 Jun 17;121(6):837-48.

2.
3.

Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.

Hinshelwood RA, Huschtscha LI, Melki J, Stirzaker C, Abdipranoto A, Vissel B, Ravasi T, Wells CA, Hume DA, Reddel RR, Clark SJ.

Cancer Res. 2007 Dec 15;67(24):11517-27.

4.

Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.

Choi HJ, Chung TW, Kang SK, Lee YC, Ko JH, Kim JG, Kim CH.

Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.

PMID:
16574813
5.

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.

Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K, Tokino T.

Gastroenterology. 2005 Jul;129(1):156-69.

PMID:
16012945
6.
8.

Evi1 is a survival factor which conveys resistance to both TGFbeta- and taxol-mediated cell death via PI3K/AKT.

Liu Y, Chen L, Ko TC, Fields AP, Thompson EA.

Oncogene. 2006 Jun 15;25(25):3565-75. Epub 2006 Feb 6.

PMID:
16462766
9.

Genetic ablation of a candidate tumor suppressor gene, Rest, does not promote mouse colon carcinogenesis.

Hatano Y, Yamada Y, Hata K, Phutthaphadoong S, Aoki H, Hara A.

Cancer Sci. 2011 Sep;102(9):1659-64. doi: 10.1111/j.1349-7006.2011.02006.x. Epub 2011 Jul 21.

11.

Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway.

Ding L, Wang Z, Yan J, Yang X, Liu A, Qiu W, Zhu J, Han J, Zhang H, Lin J, Cheng L, Qin X, Niu C, Yuan B, Wang X, Zhu C, Zhou Y, Li J, Song H, Huang C, Ye Q.

J Clin Invest. 2009 Feb;119(2):349-61. doi: 10.1172/JCI35930. Epub 2009 Jan 12.

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14.

HER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cells.

Wilson CA, Cajulis EE, Green JL, Olsen TM, Chung YA, Damore MA, Dering J, Calzone FJ, Slamon DJ.

Breast Cancer Res. 2005;7(6):R1058-79. Epub 2005 Nov 8.

15.

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

Kolfschoten IG, van Leeuwen B, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Voorhoeve PM, Agami R.

Cell. 2005 Jun 17;121(6):849-58.

16.

PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway.

Yu DH, Fan W, Liu G, Nguy V, Chatterton JE, Long S, Ke N, Meyhack B, Bruengger A, Brachat A, Wong-Staal F, Li QX.

Exp Cell Res. 2006 Apr 1;312(6):865-76. Epub 2006 Jan 17.

PMID:
16413018
17.

K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling.

Campbell PM, Groehler AL, Lee KM, Ouellette MM, Khazak V, Der CJ.

Cancer Res. 2007 Mar 1;67(5):2098-106.

18.

Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1.

Kim J, Zhang X, Rieger-Christ KM, Summerhayes IC, Wazer DE, Paulson KE, Yee AS.

J Biol Chem. 2006 Apr 21;281(16):10865-75. Epub 2006 Feb 22.

19.

Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.

Lincová E, Hampl A, Pernicová Z, Starsíchová A, Krcmár P, Machala M, Kozubík A, Soucek K.

Biochem Pharmacol. 2009 Sep 15;78(6):561-72. doi: 10.1016/j.bcp.2009.05.001. Epub 2009 May 9.

PMID:
19433066
20.

Regulation of human tyrosine hydroxylase gene by neuron-restrictive silencer factor.

Kim SM, Yang JW, Park MJ, Lee JK, Kim SU, Lee YS, Lee MA.

Biochem Biophys Res Commun. 2006 Jul 28;346(2):426-35. Epub 2006 Jun 2.

PMID:
16764822

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