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Items: 1 to 20 of 206

1.

Insulin-relaxin family peptide signaling and receptors in mouse brain membranes and neuronal cells.

Ortinau S, Lin F, Wade JD, Tregear GW, Bathgate RA, Gundlach AL.

Ann N Y Acad Sci. 2005 May;1041:211-5.

PMID:
15956710
2.

Relaxin-3, INSL5, and their receptors.

Liu C, Lovenberg TW.

Results Probl Cell Differ. 2008;46:213-37. doi: 10.1007/400_2007_055. Review.

PMID:
18236022
3.

R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization.

Kuei C, Sutton S, Bonaventure P, Pudiak C, Shelton J, Zhu J, Nepomuceno D, Wu J, Chen J, Kamme F, Seierstad M, Hack MD, Bathgate RA, Hossain MA, Wade JD, Atack J, Lovenberg TW, Liu C.

J Biol Chem. 2007 Aug 31;282(35):25425-35. Epub 2007 Jul 2.

4.

Identification of relaxin-3/INSL7 as a ligand for GPCR142.

Liu C, Chen J, Sutton S, Roland B, Kuei C, Farmer N, Sillard R, Lovenberg TW.

J Biol Chem. 2003 Dec 12;278(50):50765-70. Epub 2003 Sep 30.

5.

Localization of LGR7 (relaxin receptor) mRNA and protein in rat forebrain: correlation with relaxin binding site distribution.

Burazin TC, Johnson KJ, Ma S, Bathgate RA, Tregear GW, Gundlach AL.

Ann N Y Acad Sci. 2005 May;1041:205-10.

PMID:
15956709
6.

Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).

Halls ML, Bond CP, Sudo S, Kumagai J, Ferraro T, Layfield S, Bathgate RA, Summers RJ.

J Pharmacol Exp Ther. 2005 May;313(2):677-87. Epub 2005 Jan 12.

7.

Evolution of the signaling system in relaxin-family peptides.

Hsu SY, Semyonov J, Park JI, Chang CL.

Ann N Y Acad Sci. 2005 May;1041:520-9.

PMID:
15956755
8.

Identification of binding sites with differing affinity and potency for relaxin analogues on LGR7 and LGR8 receptors.

Halls ML, Bathgate RA, Sudo S, Kumagai J, Bond CP, Summers RJ.

Ann N Y Acad Sci. 2005 May;1041:17-21.

PMID:
15956682
9.

G-protein-coupled receptor (GPCR)-142 does not contribute to relaxin-3 binding in the mouse brain: further support that relaxin-3 is the physiological ligand for GPCR135.

Sutton SW, Bonaventure P, Kuei C, Nepomuceno D, Wu J, Zhu J, Lovenberg TW, Liu C.

Neuroendocrinology. 2005;82(3-4):139-50. Epub 2006 Jan 13.

PMID:
16679775
10.

Recent progress in relaxin-3-related research.

Liu C, Bonaventure P, Sutton SW, Chen J, Kuei C, Nepomuceno D, Lovenberg TW.

Ann N Y Acad Sci. 2005 May;1041:47-60. Review.

PMID:
15956687
11.

Identification and characterization of the mouse and rat relaxin receptors as the novel orthologues of human leucine-rich repeat-containing G-protein-coupled receptor 7.

Scott DJ, Layfield S, Riesewijk A, Morita H, Tregear GW, Bathgate RA.

Clin Exp Pharmacol Physiol. 2004 Nov;31(11):828-32.

PMID:
15566402
12.

Relaxin family peptide receptors RXFP1 and RXFP2 modulate cAMP signaling by distinct mechanisms.

Halls ML, Bathgate RA, Summers RJ.

Mol Pharmacol. 2006 Jul;70(1):214-26. Epub 2006 Mar 28.

13.

Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.

Liu C, Chen J, Kuei C, Sutton S, Nepomuceno D, Bonaventure P, Lovenberg TW.

Mol Pharmacol. 2005 Jan;67(1):231-40. Epub 2004 Oct 1.

14.

Receptors for relaxin family peptides.

Bathgate RA, Ivell R, Sanborn BM, Sherwood OD, Summers RJ.

Ann N Y Acad Sci. 2005 May;1041:61-76. Review.

PMID:
15956688
15.

Roles of the receptor, the ligand, and the cell in the signal transduction pathways utilized by the relaxin family peptide receptors 1-3.

Summers RJ, Bathgate RA, Wade JD, van der Westhuizen ET, Halls ML.

Ann N Y Acad Sci. 2009 Apr;1160:99-104. doi: 10.1111/j.1749-6632.2009.03828.x.

PMID:
19416167
16.

Activation of relaxin-related receptors by short, linear peptides derived from a collagen-containing precursor.

Shemesh R, Hermesh C, Toporik A, Levine Z, Novik A, Wool A, Kliger Y, Rosenberg A, Bathgate RA, Cohen Y.

Ann N Y Acad Sci. 2009 Apr;1160:78-86. doi: 10.1111/j.1749-6632.2009.03827.x.

PMID:
19416163
17.

LGR7-truncate is a splice variant of the relaxin receptor LGR7 and is a relaxin antagonist in vitro.

Scott DJ, Tregear GW, Bathgate RA.

Ann N Y Acad Sci. 2005 May;1041:22-6.

PMID:
15956683
18.

H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.

Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RA, Hsueh AJ.

J Biol Chem. 2003 Mar 7;278(10):7855-62. Epub 2002 Dec 27.

19.

Membrane receptors: structure and function of the relaxin family peptide receptors.

Kong RC, Shilling PJ, Lobb DK, Gooley PR, Bathgate RA.

Mol Cell Endocrinol. 2010 May 14;320(1-2):1-15. doi: 10.1016/j.mce.2010.02.003. Epub 2010 Feb 6. Review.

PMID:
20138959
20.

International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.

Bathgate RA, Ivell R, Sanborn BM, Sherwood OD, Summers RJ.

Pharmacol Rev. 2006 Mar;58(1):7-31. Review.

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