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Items: 1 to 20 of 194

1.

Identification of binding sites with differing affinity and potency for relaxin analogues on LGR7 and LGR8 receptors.

Halls ML, Bathgate RA, Sudo S, Kumagai J, Bond CP, Summers RJ.

Ann N Y Acad Sci. 2005 May;1041:17-21.

PMID:
15956682
2.

Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).

Halls ML, Bond CP, Sudo S, Kumagai J, Ferraro T, Layfield S, Bathgate RA, Summers RJ.

J Pharmacol Exp Ther. 2005 May;313(2):677-87. Epub 2005 Jan 12.

3.

H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.

Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RA, Hsueh AJ.

J Biol Chem. 2003 Mar 7;278(10):7855-62. Epub 2002 Dec 27.

4.

Studies on soluble ectodomain proteins of relaxin (LGR7) and insulin 3 (LGR8) receptors.

Yan Y, Cai J, Fu P, Layfield S, Ferraro T, Kumagai J, Sudo S, Tang JG, Giannakis E, Tregear GW, Wade JD, Bathgate RA.

Ann N Y Acad Sci. 2005 May;1041:35-9.

PMID:
15956685
5.

Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.

Muda M, He C, Martini PG, Ferraro T, Layfield S, Taylor D, Chevrier C, Schweickhardt R, Kelton C, Ryan PL, Bathgate RA.

Mol Hum Reprod. 2005 Aug;11(8):591-600. Epub 2005 Jul 28.

PMID:
16051677
6.

Relaxin receptors in hepatic stellate cells and cirrhotic liver.

Bennett RG, Dalton SR, Mahan KJ, Gentry-Nielsen MJ, Hamel FG, Tuma DJ.

Biochem Pharmacol. 2007 Apr 1;73(7):1033-40. Epub 2006 Dec 10.

PMID:
17214975
7.

LGR7-truncate is a splice variant of the relaxin receptor LGR7 and is a relaxin antagonist in vitro.

Scott DJ, Tregear GW, Bathgate RA.

Ann N Y Acad Sci. 2005 May;1041:22-6.

PMID:
15956683
8.

Characterization of the rat INSL3 receptor.

Scott DJ, Fu P, Shen PJ, Gundlach A, Layfield S, Riesewijk A, Tomiyama H, Hutson JM, Tregear GW, Bathgate RA.

Ann N Y Acad Sci. 2005 May;1041:13-6.

PMID:
15956681
9.

Relaxin receptor expression in hepatic stellate cells and in cirrhotic rat liver tissue.

Bennett RG, Mahan KJ, Gentry-Nielsen MJ, Tuma DJ.

Ann N Y Acad Sci. 2005 May;1041:185-9.

PMID:
15956705
10.

Relaxin research in the postgenomic era.

Kawamura K, Sudo S, Kumagai J, Pisarska M, Hsu SY, Bathgate R, Wade J, Hsueh AJ.

Ann N Y Acad Sci. 2005 May;1041:1-7. Review.

PMID:
15956679
11.

Identification and characterization of the mouse and rat relaxin receptors as the novel orthologues of human leucine-rich repeat-containing G-protein-coupled receptor 7.

Scott DJ, Layfield S, Riesewijk A, Morita H, Tregear GW, Bathgate RA.

Clin Exp Pharmacol Physiol. 2004 Nov;31(11):828-32.

PMID:
15566402
12.

Activation of relaxin-related receptors by short, linear peptides derived from a collagen-containing precursor.

Shemesh R, Hermesh C, Toporik A, Levine Z, Novik A, Wool A, Kliger Y, Rosenberg A, Bathgate RA, Cohen Y.

Ann N Y Acad Sci. 2009 Apr;1160:78-86. doi: 10.1111/j.1749-6632.2009.03827.x.

PMID:
19416163
13.

Insulin-relaxin family peptide signaling and receptors in mouse brain membranes and neuronal cells.

Ortinau S, Lin F, Wade JD, Tregear GW, Bathgate RA, Gundlach AL.

Ann N Y Acad Sci. 2005 May;1041:211-5.

PMID:
15956710
14.

Relaxin-3, INSL5, and their receptors.

Liu C, Lovenberg TW.

Results Probl Cell Differ. 2008;46:213-37. doi: 10.1007/400_2007_055. Review.

PMID:
18236022
15.

Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.

Scott DJ, Layfield S, Yan Y, Sudo S, Hsueh AJ, Tregear GW, Bathgate RA.

J Biol Chem. 2006 Nov 17;281(46):34942-54. Epub 2006 Sep 8.

16.

Genetic targeting of relaxin and insl3 signaling in mice.

Feng S, Bogatcheva NV, Kamat AA, Agoulnik AI.

Ann N Y Acad Sci. 2005 May;1041:82-90.

PMID:
15956690
17.

Localization of LGR7 (relaxin receptor) mRNA and protein in rat forebrain: correlation with relaxin binding site distribution.

Burazin TC, Johnson KJ, Ma S, Bathgate RA, Tregear GW, Gundlach AL.

Ann N Y Acad Sci. 2005 May;1041:205-10.

PMID:
15956709
18.

Defining the LGR8 residues involved in binding insulin-like peptide 3.

Scott DJ, Wilkinson TN, Zhang S, Ferraro T, Wade JD, Tregear GW, Bathgate RA.

Mol Endocrinol. 2007 Jul;21(7):1699-712. Epub 2007 May 1.

PMID:
17473281
19.

Coevolution of the relaxin-like peptides and their receptors.

Wilkinson TN, Speed TP, Tregear GW, Bathgate RA.

Ann N Y Acad Sci. 2005 May;1041:534-9.

PMID:
15956757
20.

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors.

Hossain MA, Rosengren KJ, Haugaard-J├Ânsson LM, Zhang S, Layfield S, Ferraro T, Daly NL, Tregear GW, Wade JD, Bathgate RA.

J Biol Chem. 2008 Jun 20;283(25):17287-97. doi: 10.1074/jbc.M801911200. Epub 2008 Apr 22.

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