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Items: 1 to 20 of 134

1.

A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma.

Kerley-Hamilton JS, Pike AM, Li N, DiRenzo J, Spinella MJ.

Oncogene. 2005 Sep 8;24(40):6090-100.

PMID:
15940259
2.

Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells.

Mao P, Hever MP, Niemaszyk LM, Haghkerdar JM, Yanco EG, Desai D, Beyrouthy MJ, Kerley-Hamilton JS, Freemantle SJ, Spinella MJ.

J Biol Chem. 2011 Jun 3;286(22):19381-91. doi: 10.1074/jbc.M111.218040.

3.

Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function.

Curtin JC, Dragnev KH, Sekula D, Christie AJ, Dmitrovsky E, Spinella MJ.

Oncogene. 2001 May 3;20(20):2559-69.

4.

p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin.

Gutekunst M, Oren M, Weilbacher A, Dengler MA, Markwardt C, Thomale J, Aulitzky WE, van der Kuip H.

PLoS One. 2011 Apr 21;6(4):e19198. doi: 10.1371/journal.pone.0019198.

5.

Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation.

Schweyer S, Soruri A, Meschter O, Heintze A, Zschunke F, Miosge N, Thelen P, Schlott T, Radzun HJ, Fayyazi A.

Br J Cancer. 2004 Aug 2;91(3):589-98.

6.

Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistance.

Mueller T, Mueller LP, Luetzkendorf J, Voigt W, Simon H, Schmoll HJ.

Tumour Biol. 2006;27(2):71-83.

PMID:
16557044
7.

[Analysis of gene expression of human tumor cells in testicular tumor].

Niclas C, Sparwasser C.

Urologe A. 2007 Sep;46(9):1185. German. No abstract available.

PMID:
17690861
8.

Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin.

Grande L, Bretones G, Rosa-Garrido M, Garrido-Martin EM, Hernandez T, Fraile S, Botella L, de Alava E, Vidal A, Garcia del Muro X, Villanueva A, Delgado MD, Fernandez-Luna JL.

J Biol Chem. 2012 Aug 3;287(32):26495-505. doi: 10.1074/jbc.M112.376319.

9.

Revisiting DNA damage repair, p53-mediated apoptosis and cisplatin sensitivity in germ cell tumors.

Cavallo F, Feldman DR, Barchi M.

Int J Dev Biol. 2013;57(2-4):273-80. doi: 10.1387/ijdb.130135mb. Review.

10.

Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct-4.

Gutekunst M, Mueller T, Weilbacher A, Dengler MA, Bedke J, Kruck S, Oren M, Aulitzky WE, van der Kuip H.

Cancer Res. 2013 Mar 1;73(5):1460-9. doi: 10.1158/0008-5472.CAN-12-2876.

11.
12.

The relative activity of cisplatin, oxaliplatin and satraplatin in testicular germ cell tumour sensitive and resistant cell lines.

Perry J, Powles T, Shamash J, Veerupillai A, McGrowder E, Noel E, Lu YJ, Oliver T, Joel S.

Cancer Chemother Pharmacol. 2009 Oct;64(5):925-33. doi: 10.1007/s00280-009-0944-6.

PMID:
19263053
13.

Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model.

Jørgensen A, Blomberg Jensen M, Nielsen JE, Juul A, Rajpert-De Meyts E.

J Steroid Biochem Mol Biol. 2013 Jul;136:238-46. doi: 10.1016/j.jsbmb.2012.10.008.

PMID:
23098692
14.
15.

Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.

Biswal BK, Beyrouthy MJ, Hever-Jardine MP, Armstrong D, Tomlinson CR, Christensen BC, Marsit CJ, Spinella MJ.

PLoS One. 2012;7(12):e53003. doi: 10.1371/journal.pone.0053003.

16.

Seladin-1 and testicular germ cell tumours: new insights into cisplatin responsiveness.

Nuti F, Luciani P, Marinari E, Erdei E, Bak M, Deledda C, Rosati F, Mazzinghi B, Danza G, Stoop H, Looijenga LH, Peri A, Serio M, Krausz C.

J Pathol. 2009 Dec;219(4):491-500. doi: 10.1002/path.2622.

PMID:
19844922
17.

p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells.

Zamble DB, Jacks T, Lippard SJ.

Proc Natl Acad Sci U S A. 1998 May 26;95(11):6163-8.

18.

An oncofetal and developmental perspective on testicular germ cell cancer.

Rijlaarsdam MA, Looijenga LH.

Semin Cancer Biol. 2014 Dec;29:59-74. doi: 10.1016/j.semcancer.2014.07.003. Review.

PMID:
25066859
19.

Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.

Wermann H, Stoop H, Gillis AJ, Honecker F, van Gurp RJ, Ammerpohl O, Richter J, Oosterhuis JW, Bokemeyer C, Looijenga LH.

J Pathol. 2010 Aug;221(4):433-42. doi: 10.1002/path.2725.

PMID:
20593487
20.
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