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15920715,11843990,17664405,19246907,18391486,16574032,17988434,18984956,12442882,19176895,11524468,16083542,14716693,15596605,17132971,19735164,17199235,15760632,14734594,20634594,20395684,22915447,16508298,15462693,14716700,17047484,19700948,17622761,22959283,16626752,17974866,20678673,15084792,17514186,20597141,15207427,16676290,12837144,12757558,23411693,18631958,17582225,15465097,16163744,16129386,21258153,28157100,17312368,15496222,20558849,14618549,20377821,12970516,12971832,15601392,17471598,16192723,22572767,19751915,21992111,17714966,17939763,15537482,16594943,17664404,11044775,15922506,19561444,10325453,17132970,12670060,9588436,19948364,11921156,26967222,29923184,19969381,20872778,10556869,14715043,17625502,19738386,15883262,12469988,19949165,16581404,19492974,7654110,14974068,16393430,15326237,15762015,15700322,18257603,19623601,19874395,21335973,12672860,20534179,24436135,14626696,14716694,9443470,16930364,16816014,10354658,20184936,22397651,14986682,12789681,16599649,14561111,14594748,16670247,19630974,16103669,15252826,12166542,22930699,15537474,10463520,9853200,15863734,12673604,15027039,19996880,22829268,15220031,19538824,26066622,21364371,11819153,20738808,14986699,23322144,18296124,9597987,15990426,15965198,27756421,20102379,16437430,29318278,11502918,19571727,17760991,15158578,12397141,12917900,12117079,23316713,20224285,19347685,20129316,9617511,15852444,21199965,25918972,26680338,26402762,15969871,24898643,17545739,9595967,21648328,23949147,17914039,10915420,15853610,26515660,15622018,22281004,12181083,12296613,15829527,25919986,9452942,26923256,24418055,15912820,15605367,12139366,26967214,25624417,15134388,19786776,10420948,16478570,15292648,11255446,23909965,20170698,11351141,15763392,20825496,8915035,20332637,23711226,20859244,12672174,14663655,12151908,17472546,12510954,10960883,12457078,9876215,12939421,21679156,15200752,25079803,19593181,10216789,14533127,10622675,10796620,15055749,21955192,15534239,23733403,18288936,12841930,19606472,24643135,17597552,21098979,12567159,15352644,17480241,19838862,25297016,12714795,12139369,15920713,15537522,11921158,21399485,17005066,15852461,15254918,10747691,11606667,25310993,15449367,16832078,14626697,15326236,10090427,23110864,24322964,9812142,25024314,15277611,16062097,19420308,16974095,14687442,11196347,11249555,16856114,16863459,14651435,19042161,26114924,14560059,29622037,26402119,19221429,23742728,23979024,24315979,12626851,22513699,18198262,12094822,28138837,22492589,16767418,15237280,17627484,15701776,15140813,28419192,11502917,15791348,9489056,10332937,8701750,10867446,18088076,18042476,15472777,10793322,15156547,15883258,20733306,10323651,18665662,17052048,16780671,28673322,24073978,11519239,15102875,22465999,15832031,10937606,22752489,10338105,26226884,22792683,22175653,18230972,10848060,15800138,21159050,15107192,25596420,29319499,17068392,11441374,19812469,22106763,16928344,10447153,16872233,15603468,16483272,9580729,29284465,15966445,9475825,12023410,10804074,24785550,14533120,15722369,15596427,25656634,19836169,20395618,11817515,11925682,11183967,12497561,19186568,15472779,15788218,12834513,26114729,15013568,23786741,22687392,25726780,12611746,21955815,21714757,21495523,24492450,26482056,12111620,16025771,20201245,27739182,10407214,15677877,24661498,12417372,23108692,25588408,24732387,20500802,29635383,12973745,9108896,28891516,22445625,9876403,21108390,12801387,17557224,15584119,14680445,12410907,12001652,12117361,22330824,10555660,19066429,24785894,15760641,21281700,22449664,29716655,19383979,10521169,11789125,25380803,11889261,16260821,12716251,23462265,23609381,14758580,12469005,12480791,21159055,22718435,24456283,18518863,20515010,1609044,12380156,12682346,15896220,22606044,29771687,10984725,15852437,21044773,9339267,21157021,15324524,27288803,31182351,9876959,34120898,25516360,12147570,21689411,20402542,15277606,18341753,21295494,14753643,20664535,23102979,24107805,19481822,12671528,15260910,23472619,15472778,15084794,21299848,21666432,16144532,24192578,10803860,28035924,16494088,29993162,12187372,11830754,1775603,24969819,10484967,14741060,17148938,11585854,10637404,10950240,33771205,20831025,11044869,18808602,10767734,2049365,10634454,11488374,11738011,26161001,21519001,12243208,16876651,18172910,22217339,22681723,10678137,10695652,12640228,24288512,19884584,14967774,10862247,9773102,20699079,22500712,22217618,12688400,10078713,12449096,12813848,25920742,15204315,18667813,19262966,19024233,21592048,26392193,19879468,19528519,36894171,19371449,12142731,11502915,22805083,15728444,18215726,15086675,11257811,16845507,19407728,12673601,17718684,15496217,21309696,22766770,26402513,18645736,22333201,17519086,24107324,31985467,26656642,19160328,25316430,29710726,22886013,35099343,33579850,12833312,26420637,22994615,27780331,17595427,24710130,33928754,15000918,3479525,26876309,21612646,10861924,10539126,35124395,15554484,10608295,12833225,15824717,25991927,26297092,20810998,15763393,14627060,14533139,14617718,26336931,11582975,11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Results by year

Year	Number of Results
1986	1
1987	2
1989	1
1990	3
1991	3
1992	3
1993	5
1994	4
1995	2
1996	7
1997	7
1998	36
1999	36
2000	45
2001	29
2002	55
2003	72
2004	85
2005	66
2006	45
2007	40
2008	40
2009	56
2010	46
2011	50
2012	55
2013	39
2014	31
2015	49
2016	33
2017	26
2018	22
2019	19
2020	18
2021	21
2022	15
2023	4
2024	0

997 results

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Results by year

Page 1

Efficacy and safety of donepezil in patients with more severe Alzheimer's disease: a subgroup analysis from a randomized, placebo-controlled trial.

Feldman H, Gauthier S, Hecker J, Vellas B, Xu Y, Ieni JR, Schwam EM; Donepezil MSAD Study Investigators Group. Feldman H, et al. Int J Geriatr Psychiatry. 2005 Jun;20(6):559-69. doi: 10.1002/gps.1325. Int J Geriatr Psychiatry. 2005. PMID: 15920715 Clinical Trial.

A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting.

Tariot PN, Cummings JL, Katz IR, Mintzer J, Perdomo CA, Schwam EM, Whalen E. Tariot PN, et al. J Am Geriatr Soc. 2001 Dec;49(12):1590-9. J Am Geriatr Soc. 2001. PMID: 11843990 Clinical Trial.

Donepezil preserves cognition and global function in patients with severe Alzheimer disease.

Black SE, Doody R, Li H, McRae T, Jambor KM, Xu Y, Sun Y, Perdomo CA, Richardson S. Black SE, et al. Neurology. 2007 Jul 31;69(5):459-69. doi: 10.1212/01.wnl.0000266627.96040.5a. Neurology. 2007. PMID: 17664405 Clinical Trial.

Long-term safety and efficacy of donepezil in patients with severe Alzheimer's disease: results from a 52-week, open-label, multicenter, extension study in Japan.

Homma A, Imai Y, Tago H, Asada T, Shigeta M, Iwamoto T, Takita M, Arimoto I, Koma H, Takase T, Ohbayashi T. Homma A, et al. Dement Geriatr Cogn Disord. 2009;27(3):232-9. doi: 10.1159/000203887. Epub 2009 Feb 25. Dement Geriatr Cogn Disord. 2009. PMID: 19246907 Clinical Trial.

Donepezil treatment of patients with severe Alzheimer's disease in a Japanese population: results from a 24-week, double-blind, placebo-controlled, randomized trial.

Homma A, Imai Y, Tago H, Asada T, Shigeta M, Iwamoto T, Takita M, Arimoto I, Koma H, Ohbayashi T. Homma A, et al. Dement Geriatr Cogn Disord. 2008;25(5):399-407. doi: 10.1159/000122961. Epub 2008 Apr 3. Dement Geriatr Cogn Disord. 2008. PMID: 18391486 Clinical Trial.

Effect of age on response to rivastigmine or donepezil in patients with Alzheimer's disease.

Bullock R, Bergman H, Touchon J, Gambina G, He Y, Nagel J, Lane R. Bullock R, et al. Curr Med Res Opin. 2006 Mar;22(3):483-94. doi: 10.1185/030079906X89685. Curr Med Res Opin. 2006. PMID: 16574032 Clinical Trial.

Effectiveness of open-label donepezil treatment in patients with Alzheimer's disease discontinuing memantine monotherapy.

Sakka P, Tsolaki M, Hort J, Hager K, Soininen H, López Pousa S, Li C, Schwam E. Sakka P, et al. Curr Med Res Opin. 2007 Dec;23(12):3153-65. doi: 10.1185/030079907X242773. Curr Med Res Opin. 2007. PMID: 17988434 Clinical Trial.

Donepezil treatment of severe Alzheimer's disease in nursing home settings. A responder analysis.

Jelic V, Haglund A, Kowalski J, Langworth S, Winblad B. Jelic V, et al. Dement Geriatr Cogn Disord. 2008;26(5):458-66. doi: 10.1159/000167267. Epub 2008 Nov 4. Dement Geriatr Cogn Disord. 2008. PMID: 18984956

Functional, cognitive and behavioral effects of donepezil in patients with moderate Alzheimer's disease.

Gauthier S, Feldman H, Hecker J, Vellas B, Emir B, Subbiah P; Donepezil MSAD Study Investigators' Group. Gauthier S, et al. Curr Med Res Opin. 2002;18(6):347-54. doi: 10.1185/030079902125001029. Curr Med Res Opin. 2002. PMID: 12442882 Clinical Trial.

Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial.

Doody RS, Ferris SH, Salloway S, Sun Y, Goldman R, Watkins WE, Xu Y, Murthy AK. Doody RS, et al. Neurology. 2009 May 5;72(18):1555-61. doi: 10.1212/01.wnl.0000344650.95823.03. Epub 2009 Jan 28. Neurology. 2009. PMID: 19176895 Clinical Trial.

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