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Items: 1 to 20 of 117

1.

Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.

Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H.

Diabetes. 2005 Jun;54(6):1692-7.

2.

Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.

Frøsig C, Rose AJ, Treebak JT, Kiens B, Richter EA, Wojtaszewski JF.

Diabetes. 2007 Aug;56(8):2093-102. Epub 2007 May 18.

3.

Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

Højlund K, Glintborg D, Andersen NR, Birk JB, Treebak JT, Frøsig C, Beck-Nielsen H, Wojtaszewski JF.

Diabetes. 2008 Feb;57(2):357-66. Epub 2007 Oct 31.

4.

Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

Storgaard H, Song XM, Jensen CB, Madsbad S, Björnholm M, Vaag A, Zierath JR.

Diabetes. 2001 Dec;50(12):2770-8. Erratum in: Diabetes 2002 Feb;51(2):552.

5.

Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.

Kuoppamaa H, Skrobuk P, Sihvo M, Hiukka A, Chibalin AV, Zierath JR, Koistinen HA.

Diabetes Metab Res Rev. 2008 Oct;24(7):554-62. doi: 10.1002/dmrr.883.

PMID:
18615850
6.

Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats.

Song XM, Kawano Y, Krook A, Ryder JW, Efendic S, Roth RA, Wallberg-Henriksson H, Zierath JR.

Diabetes. 1999 Mar;48(3):664-70.

PMID:
10078575
7.

Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

Shao J, Yamashita H, Qiao L, Friedman JE.

J Endocrinol. 2000 Oct;167(1):107-15.

8.

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

Kramer HF, Witczak CA, Taylor EB, Fujii N, Hirshman MF, Goodyear LJ.

J Biol Chem. 2006 Oct 20;281(42):31478-85. Epub 2006 Aug 25.

9.

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.

10.

Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients.

Karlsson HK, Ahlsén M, Zierath JR, Wallberg-Henriksson H, Koistinen HA.

Diabetes. 2006 May;55(5):1283-8.

11.

Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.

Karlsson HK, Hällsten K, Björnholm M, Tsuchida H, Chibalin AV, Virtanen KA, Heinonen OJ, Lönnqvist F, Nuutila P, Zierath JR.

Diabetes. 2005 May;54(5):1459-67.

12.

Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients.

Cozzone D, Fröjdö S, Disse E, Debard C, Laville M, Pirola L, Vidal H.

Diabetologia. 2008 Mar;51(3):512-21. doi: 10.1007/s00125-007-0913-8. Epub 2008 Jan 18.

PMID:
18204829
13.

Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.

Kramer HF, Witczak CA, Fujii N, Jessen N, Taylor EB, Arnolds DE, Sakamoto K, Hirshman MF, Goodyear LJ.

Diabetes. 2006 Jul;55(7):2067-76.

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17.

Acute selective glycogen synthase kinase-3 inhibition enhances insulin signaling in prediabetic insulin-resistant rat skeletal muscle.

Dokken BB, Sloniger JA, Henriksen EJ.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1188-94. Epub 2005 Jan 25.

18.

Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects.

Krook A, Roth RA, Jiang XJ, Zierath JR, Wallberg-Henriksson H.

Diabetes. 1998 Aug;47(8):1281-6.

PMID:
9703329
19.

Restoring AS160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids.

Alkhateeb H, Chabowski A, Glatz JF, Gurd B, Luiken JJ, Bonen A.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1056-66. doi: 10.1152/ajpendo.90908.2008. Epub 2009 Sep 1.

20.

Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes.

Meyer MM, Levin K, Grimmsmann T, Perwitz N, Eirich A, Beck-Nielsen H, Klein HH.

Diabetes. 2002 Sep;51(9):2691-7.

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