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Items: 1 to 20 of 349

1.

Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation.

Viswanathan K, Narang S, Hinderlich S, Lee YC, Betenbaugh MJ.

Biochemistry. 2005 May 24;44(20):7526-34.

PMID:
15895995
2.

Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them.

Viswanathan K, Lawrence S, Hinderlich S, Yarema KJ, Lee YC, Betenbaugh MJ.

Biochemistry. 2003 Dec 30;42(51):15215-25.

PMID:
14690432
3.

Cloning and expression of human sialic acid pathway genes to generate CMP-sialic acids in insect cells.

Lawrence SM, Huddleston KA, Tomiya N, Nguyen N, Lee YC, Vann WF, Coleman TA, Betenbaugh MJ.

Glycoconj J. 2001 Mar;18(3):205-13.

PMID:
11602804
4.
5.

Genetic engineering of Escherichia coli for the economical production of sialylated oligosaccharides.

Fierfort N, Samain E.

J Biotechnol. 2008 Apr 30;134(3-4):261-5. doi: 10.1016/j.jbiotec.2008.02.010. Epub 2008 Mar 10.

PMID:
18378033
6.

Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.

Reinke SO, Lehmer G, Hinderlich S, Reutter W.

Biol Chem. 2009 Jul;390(7):591-9. doi: 10.1515/BC.2009.073. Review.

PMID:
19426133
7.

Engineering Sialic Acid Synthesis Ability in Insect Cells.

Viswanathan K, Narang S, Betenbaugh MJ.

Methods Mol Biol. 2015;1321:171-8. doi: 10.1007/978-1-4939-2760-9_12.

PMID:
26082222
9.

Biosynthesis of N-acetylneuraminic acid in cells lacking UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.

Hinderlich S, Berger M, Keppler OT, Pawlita M, Reutter W.

Biol Chem. 2001 Feb;382(2):291-7.

PMID:
11308027
10.

Nuclear localization signal of murine CMP-Neu5Ac synthetase includes residues required for both nuclear targeting and enzymatic activity.

Munster AK, Weinhold B, Gotza B, Muhlenhoff M, Frosch M, Gerardy-Schahn R.

J Biol Chem. 2002 May 31;277(22):19688-96. Epub 2002 Mar 13.

11.
12.

Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells.

Bork K, Reutter W, Weidemann W, Horstkorte R.

FEBS Lett. 2007 Sep 4;581(22):4195-8. Epub 2007 Aug 3.

13.

Preparative enzymatic synthesis of activated neuraminic acid by using a microbial enzyme.

Kittelmann M, Klein T, Kragl U, Wandrey C, Ghisalba O.

Ann N Y Acad Sci. 1992 Nov 30;672:444-50.

PMID:
1476385
14.

Molecular cloning of a unique CMP-sialic acid synthetase that effectively utilizes both deaminoneuraminic acid (KDN) and N-acetylneuraminic acid (Neu5Ac) as substrates.

Nakata D, Münster AK, Gerardy-Schahn R, Aoki N, Matsuda T, Kitajima K.

Glycobiology. 2001 Aug;11(8):685-92.

PMID:
11479279
15.

Construction of a functional CMP-sialic acid biosynthesis pathway in Arabidopsis.

Castilho A, Pabst M, Leonard R, Veit C, Altmann F, Mach L, Glössl J, Strasser R, Steinkellner H.

Plant Physiol. 2008 May;147(1):331-9. doi: 10.1104/pp.108.117572. Epub 2008 Mar 7.

16.

High-level expression of recombinant Neisseria CMP-sialic acid synthetase in Escherichia coli.

Karwaski MF, Wakarchuk WW, Gilbert M.

Protein Expr Purif. 2002 Jul;25(2):237-40.

PMID:
12135555
17.
19.

A transgenic insect cell line engineered to produce CMP-sialic acid and sialylated glycoproteins.

Aumiller JJ, Hollister JR, Jarvis DL.

Glycobiology. 2003 Jun;13(6):497-507. Epub 2003 Feb 20.

20.

Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes.

Son YD, Jeong YT, Park SY, Kim JH.

Glycobiology. 2011 Aug;21(8):1019-28. doi: 10.1093/glycob/cwr034. Epub 2011 Mar 24.

PMID:
21436238

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