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Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma.

Lai SY, Childs EE, Xi S, Coppelli FM, Gooding WE, Wells A, Ferris RL, Grandis JR.

Oncogene. 2005 Jun 23;24(27):4442-9. Erratum in: Oncogene. 2005 Dec 8;24(55):8216.


Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.

Chin H, Arai A, Wakao H, Kamiyama R, Miyasaka N, Miura O.

Blood. 1998 May 15;91(10):3734-45.


Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway.

Okutani Y, Kitanaka A, Tanaka T, Kamano H, Ohnishi H, Kubota Y, Ishida T, Takahara J.

Oncogene. 2001 Oct 4;20(45):6643-50.


Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma.

Mohyeldin A, Lu H, Dalgard C, Lai SY, Cohen N, Acs G, Verma A.

Neoplasia. 2005 May;7(5):537-43.


Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways.

Wakao H, Harada N, Kitamura T, Mui AL, Miyajima A.

EMBO J. 1995 Jun 1;14(11):2527-35.


Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cells.

Yamamura Y, Senda H, Kageyama Y, Matsuzaki T, Noda M, Ikawa Y.

Mol Cell Biol. 1998 Mar;18(3):1172-80.


Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line.

Shi Z, Hodges VM, Dunlop EA, Percy MJ, Maxwell AP, El-Tanani M, Lappin TR.

Mol Cancer Res. 2010 Apr;8(4):615-26. doi: 10.1158/1541-7786.MCR-09-0264. Epub 2010 Mar 30.


[Proliferative signal transmission mediated by EpoR in leukemic cell lines].

Fan H, Kanji S, Zhai M.

Zhonghua Xue Ye Xue Za Zhi. 2000 Jun;21(6):294-7. Chinese.


A possible involvement of Stat5 in erythropoietin-induced hemoglobin synthesis.

Wakao H, Chida D, Damen JE, Krystal G, Miyajima A.

Biochem Biophys Res Commun. 1997 May 8;234(1):198-205.


Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines.

Silva M, Benito A, Sanz C, Prosper F, Ekhterae D, Nuñez G, Fernandez-Luna JL.

J Biol Chem. 1999 Aug 6;274(32):22165-9.


The critical role of SRC homology domain 2-containing tyrosine phosphatase-1 in recombinant human erythropoietin hyporesponsive anemia in chronic hemodialysis patients.

Akagi S, Ichikawa H, Okada T, Sarai A, Sugimoto T, Morimoto H, Kihara T, Yano A, Nakao K, Nagake Y, Wada J, Makino H.

J Am Soc Nephrol. 2004 Dec;15(12):3215-24.


Low doses of EPO activate MAP kinases but not JAK2-STAT5 in rat vascular smooth muscle cells.

Ammarguellat F, Llovera M, Kelly PA, Goffin V.

Biochem Biophys Res Commun. 2001 Jun 22;284(4):1031-8.


Erythropoietin stimulates proliferation and interferes with differentiation of myoblasts.

Ogilvie M, Yu X, Nicolas-Metral V, Pulido SM, Liu C, Ruegg UT, Noguchi CT.

J Biol Chem. 2000 Dec 15;275(50):39754-61.

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