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Items: 1 to 20 of 149

1.

Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases.

Kanemori Y, Uto K, Sagata N.

Proc Natl Acad Sci U S A. 2005 May 3;102(18):6279-84. Epub 2005 Apr 21.

2.

The extracellular signal-regulated kinase-mitogen-activated protein kinase pathway phosphorylates and targets Cdc25A for SCF beta-TrCP-dependent degradation for cell cycle arrest.

Isoda M, Kanemori Y, Nakajo N, Uchida S, Yamashita K, Ueno H, Sagata N.

Mol Biol Cell. 2009 Apr;20(8):2186-95. doi: 10.1091/mbc.E09-01-0008. Epub 2009 Feb 25.

3.

Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner.

Ray D, Terao Y, Nimbalkar D, Chu LH, Donzelli M, Tsutsui T, Zou X, Ghosh AK, Varga J, Draetta GF, Kiyokawa H.

Mol Cell Biol. 2005 Apr;25(8):3338-47.

4.

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage.

Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello NV, Hershko A, Pagano M, Draetta GF.

Nature. 2003 Nov 6;426(6962):87-91.

PMID:
14603323
5.

Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.

Jin J, Ang XL, Ye X, Livingstone M, Harper JW.

J Biol Chem. 2008 Jul 11;283(28):19322-8. doi: 10.1074/jbc.M802474200. Epub 2008 May 13.

6.

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.

Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, Harper JW.

Genes Dev. 2003 Dec 15;17(24):3062-74. Epub 2003 Dec 17.

7.

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro.

Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW.

Genes Dev. 1999 Feb 1;13(3):270-83. Erratum in: Genes Dev 1999 Apr 15;13(8):1050.

8.

CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation.

Piao S, Lee SJ, Xu Y, Gwak J, Oh S, Park BJ, Ha NC.

Cell Cycle. 2011 Feb 1;10(3):531-7. Epub 2011 Feb 1.

PMID:
21252624
9.

Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction.

Honaker Y, Piwnica-Worms H.

Oncogene. 2010 Jun 10;29(23):3324-34. doi: 10.1038/onc.2010.96. Epub 2010 Mar 29.

10.

Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP.

Morelli M, Dennis AF, Patton JT.

MBio. 2015 Jan 27;6(1). pii: e02490-14. doi: 10.1128/mBio.02490-14.

11.

NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint.

Melixetian M, Klein DK, Sørensen CS, Helin K.

Nat Cell Biol. 2009 Oct;11(10):1247-53. doi: 10.1038/ncb1969. Epub 2009 Sep 6.

PMID:
19734889
12.

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.

Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4419-24. Epub 2004 Mar 22.

13.

Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.

Shimuta K, Nakajo N, Uto K, Hayano Y, Okazaki K, Sagata N.

EMBO J. 2002 Jul 15;21(14):3694-703.

14.

SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4.

Strack P, Caligiuri M, Pelletier M, Boisclair M, Theodoras A, Beer-Romero P, Glass S, Parsons T, Copeland RA, Auger KR, Benfield P, Brizuela L, Rolfe M.

Oncogene. 2000 Jul 20;19(31):3529-36.

15.

Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways.

Watanabe N, Arai H, Iwasaki J, Shiina M, Ogata K, Hunter T, Osada H.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11663-8. Epub 2005 Aug 5.

16.

The ubiquitin ligase SCF(betaTrCP) regulates the degradation of the growth hormone receptor.

van Kerkhof P, Putters J, Strous GJ.

J Biol Chem. 2007 Jul 13;282(28):20475-83. Epub 2007 May 10. Erratum in: J Biol Chem. 2008 Apr 25;283(17):11860.

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19.

Inhibition of β-TrcP-dependent ubiquitination of p53 by HIV-1 Vpu promotes p53-mediated apoptosis in human T cells.

Verma S, Ali A, Arora S, Banerjea AC.

Blood. 2011 Jun 16;117(24):6600-7. doi: 10.1182/blood-2011-01-333427. Epub 2011 Apr 26.

20.

Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms.

Tsuchiya Y, Morita T, Kim M, Iemura S, Natsume T, Yamamoto M, Kobayashi A.

Mol Cell Biol. 2011 Nov;31(22):4500-12. doi: 10.1128/MCB.05663-11. Epub 2011 Sep 12.

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