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Items: 1 to 20 of 128

1.

Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.

Oliver TG, Read TA, Kessler JD, Mehmeti A, Wells JF, Huynh TT, Lin SM, Wechsler-Reya RJ.

Development. 2005 May;132(10):2425-39. Epub 2005 Apr 20.

2.

Tis21 knock-out enhances the frequency of medulloblastoma in Patched1 heterozygous mice by inhibiting the Cxcl3-dependent migration of cerebellar neurons.

Farioli-Vecchioli S, Cinà I, Ceccarelli M, Micheli L, Leonardi L, Ciotti MT, De Bardi M, Di Rocco C, Pallini R, Cavallaro S, Tirone F.

J Neurosci. 2012 Oct 31;32(44):15547-64. doi: 10.1523/JNEUROSCI.0412-12.2012.

3.

Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3.

Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F.

FASEB J. 2007 Jul;21(9):2215-25. Epub 2007 Mar 19.

PMID:
17371797
4.

Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration.

Haag D, Zipper P, Westrich V, Karra D, Pfleger K, Toedt G, Blond F, Delhomme N, Hahn M, Reifenberger J, Reifenberger G, Lichter P.

PLoS Genet. 2012;8(3):e1002572. doi: 10.1371/journal.pgen.1002572. Epub 2012 Mar 15.

5.

Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice.

Kim JY, Nelson AL, Algon SA, Graves O, Sturla LM, Goumnerova LC, Rowitch DH, Segal RA, Pomeroy SL.

Dev Biol. 2003 Nov 1;263(1):50-66.

6.

Transcriptional up-regulation of Gadd45a in Patched-associated medulloblastoma.

Kappler R, Hess I, Schlegel J, Hahn H.

Int J Oncol. 2004 Jul;25(1):113-20.

PMID:
15201996
7.

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

Wetmore C, Eberhart DE, Curran T.

Cancer Res. 2001 Jan 15;61(2):513-6.

8.

Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.

Ayrault O, Zindy F, Rehg J, Sherr CJ, Roussel MF.

Mol Cancer Res. 2009 Jan;7(1):33-40. doi: 10.1158/1541-7786.MCR-08-0369.

9.

Developmental and oncogenic effects of insulin-like growth factor-I in Ptc1+/- mouse cerebellum.

Tanori M, Santone M, Mancuso M, Pasquali E, Leonardi S, Di Majo V, Rebessi S, Saran A, Pazzaglia S.

Mol Cancer. 2010 Mar 9;9:53. doi: 10.1186/1476-4598-9-53.

10.
11.

Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation.

Pogoriler J, Millen K, Utset M, Du W.

Development. 2006 Oct;133(19):3929-37. Epub 2006 Aug 30.

12.
13.

Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.

Pazzaglia S, Tanori M, Mancuso M, Gessi M, Pasquali E, Leonardi S, Oliva MA, Rebessi S, Di Majo V, Covelli V, Giangaspero F, Saran A.

Oncogene. 2006 Sep 7;25(40):5575-80. Epub 2006 Apr 24.

PMID:
16636673
14.

Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors.

Zindy F, Uziel T, Ayrault O, Calabrese C, Valentine M, Rehg JE, Gilbertson RJ, Sherr CJ, Roussel MF.

Cancer Res. 2007 Mar 15;67(6):2676-84.

15.

A mouse model for medulloblastoma and basal cell nevus syndrome.

Corcoran RB, Scott MP.

J Neurooncol. 2001 Jul;53(3):307-18. Review.

PMID:
11718263
16.

Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.

Thomas WD, Chen J, Gao YR, Cheung B, Koach J, Sekyere E, Norris MD, Haber M, Ellis T, Wainwright B, Marshall GM.

Oncogene. 2009 Apr 2;28(13):1605-15. doi: 10.1038/onc.2009.3. Epub 2009 Feb 23.

PMID:
19234491
17.

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas.

Leung C, Lingbeek M, Shakhova O, Liu J, Tanger E, Saremaslani P, Van Lohuizen M, Marino S.

Nature. 2004 Mar 18;428(6980):337-41.

PMID:
15029199
18.

Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.

Briggs KJ, Corcoran-Schwartz IM, Zhang W, Harcke T, Devereux WL, Baylin SB, Eberhart CG, Watkins DN.

Genes Dev. 2008 Mar 15;22(6):770-85. doi: 10.1101/gad.1640908. Erratum in: Genes Dev. 2008 May 15;22(10):1410.

19.

Linking DNA damage to medulloblastoma tumorigenesis in patched heterozygous knockout mice.

Pazzaglia S, Tanori M, Mancuso M, Rebessi S, Leonardi S, Di Majo V, Covelli V, Atkinson MJ, Hahn H, Saran A.

Oncogene. 2006 Feb 23;25(8):1165-73.

PMID:
16407852
20.

Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.

Vaillant C, Valdivieso P, Nuciforo S, Kool M, Schwarzentruber-Schauerte A, Méreau H, Cabuy E, Lobrinus JA, Pfister S, Zuniga A, Frank S, Zeller R.

PLoS One. 2015 Apr 22;10(4):e0124870. doi: 10.1371/journal.pone.0124870. eCollection 2015.

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