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Items: 1 to 20 of 126

1.

Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport.

Yang CL, Zhu X, Wang Z, Subramanya AR, Ellison DH.

J Clin Invest. 2005 May;115(5):1379-87. Epub 2005 Apr 7.

2.

WNK kinases regulate thiazide-sensitive Na-Cl cotransport.

Yang CL, Angell J, Mitchell R, Ellison DH.

J Clin Invest. 2003 Apr;111(7):1039-45.

3.

The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.

Yang CL, Zhu X, Ellison DH.

J Clin Invest. 2007 Nov;117(11):3403-11.

4.

WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.

Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J.

Hypertension. 2014 Nov;64(5):1047-53. doi: 10.1161/HYPERTENSIONAHA.114.04036. Epub 2014 Aug 11.

5.

WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter.

San-Cristobal P, Ponce-Coria J, Vázquez N, Bobadilla NA, Gamba G.

Am J Physiol Renal Physiol. 2008 Oct;295(4):F1199-206. doi: 10.1152/ajprenal.90396.2008. Epub 2008 Aug 13.

6.

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension.

Hadchouel J, Soukaseum C, Büsst C, Zhou XO, Baudrie V, Zürrer T, Cambillau M, Elghozi JL, Lifton RP, Loffing J, Jeunemaitre X.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18109-14. doi: 10.1073/pnas.1006128107. Epub 2010 Oct 4.

7.

Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved.

Golbang AP, Cope G, Hamad A, Murthy M, Liu CH, Cuthbert AW, O'shaughnessy KM.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1369-76. Epub 2006 Jun 20.

8.

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):680-4. Epub 2003 Jan 6.

9.

Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.

O'Reilly M, Marshall E, Macgillivray T, Mittal M, Xue W, Kenyon CJ, Brown RW.

J Am Soc Nephrol. 2006 Sep;17(9):2402-13. Epub 2006 Aug 9.

10.

WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway.

Zhou B, Wang D, Feng X, Zhang Y, Wang Y, Zhuang J, Zhang X, Chen G, Delpire E, Gu D, Cai H.

Am J Physiol Renal Physiol. 2012 Mar 1;302(5):F533-9. doi: 10.1152/ajprenal.00032.2011. Epub 2011 Nov 23.

11.

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.

Liu Z, Xie J, Wu T, Truong T, Auchus RJ, Huang CL.

Hum Mol Genet. 2011 Mar 1;20(5):855-66. doi: 10.1093/hmg/ddq525. Epub 2010 Dec 2.

12.

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride.

Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G.

J Am Soc Nephrol. 2015 Aug;26(8):1781-6. doi: 10.1681/ASN.2014050470. Epub 2014 Dec 26.

13.

Exploring the intricate regulatory network controlling the thiazide-sensitive NaCl cotransporter (NCC).

Dimke H.

Pflugers Arch. 2011 Dec;462(6):767-77. doi: 10.1007/s00424-011-1027-1. Epub 2011 Sep 17. Review.

14.

A unifying mechanism for WNK kinase regulation of sodium-chloride cotransporter.

Huang CL, Cheng CJ.

Pflugers Arch. 2015 Nov;467(11):2235-41. doi: 10.1007/s00424-015-1708-2. Epub 2015 Apr 24. Review.

15.

Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.

Rozansky DJ, Cornwall T, Subramanya AR, Rogers S, Yang YF, David LL, Zhu X, Yang CL, Ellison DH.

J Clin Invest. 2009 Sep;119(9):2601-12. doi: 10.1172/JCI38323. Epub 2009 Aug 17.

16.

[New perspective on the role of WNK1 and WNK4 in the regulation of NaCl reabsorption and K(+) secretion by the distal nephron].

Rafael C, Chavez-Canales M, Hadchouel J.

Med Sci (Paris). 2016 Mar;32(3):274-80. doi: 10.1051/medsci/20163203012. Epub 2016 Mar 23. Review. French.

17.

Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells.

Yang SS, Yamauchi K, Rai T, Hiyama A, Sohara E, Suzuki T, Itoh T, Suda S, Sasaki S, Uchida S.

Biochem Biophys Res Commun. 2005 May 6;330(2):410-4.

PMID:
15796898
18.

Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform.

Subramanya AR, Yang CL, Zhu X, Ellison DH.

Am J Physiol Renal Physiol. 2006 Mar;290(3):F619-24. Epub 2005 Oct 4.

19.

WNK1 and WNK4 modulate CFTR activity.

Yang CL, Liu X, Paliege A, Zhu X, Bachmann S, Dawson DC, Ellison DH.

Biochem Biophys Res Commun. 2007 Feb 16;353(3):535-40. Epub 2006 Dec 15.

PMID:
17194447
20.

Identification of a novel WNK4 mutation in Chinese patients with pseudohypoaldosteronism type II.

Zhang C, Wang Z, Xie J, Yan F, Wang W, Feng X, Zhang W, Chen N.

Nephron Physiol. 2011;118(3):p53-61. doi: 10.1159/000321879. Epub 2010 Dec 24.

PMID:
21196779

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