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Items: 1 to 20 of 305

3.
4.

Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway.

Deriano L, Guipaud O, Merle-BĂ©ral H, Binet JL, Ricoul M, Potocki-Veronese G, Favaudon V, Maciorowski Z, Muller C, Salles B, Sabatier L, Delic J.

Blood. 2005 Jun 15;105(12):4776-83. Epub 2005 Feb 17.

5.

Ku70 and Rad51 vary in their importance for the repair of doxorubicin- versus etoposide-induced DNA damage.

Schonn I, Hennesen J, Dartsch DC.

Apoptosis. 2011 Apr;16(4):359-69. doi: 10.1007/s10495-010-0564-y.

PMID:
21107697
6.

Transient depletion of Ku70 and Xrcc4 by RNAi as a means to manipulate the non-homologous end-joining pathway.

Bertolini LR, Bertolini M, Anderson GB, Maga EA, Madden KR, Murray JD.

J Biotechnol. 2007 Feb 1;128(2):246-57. Epub 2006 Oct 14.

PMID:
17097754
7.

Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines.

Nolens G, Pignon JC, Koopmansch B, Elmoualij B, Zorzi W, De Pauw E, Winkler R.

Breast Cancer Res. 2009;11(6):R83. doi: 10.1186/bcr2450. Epub 2009 Nov 11.

8.

Heterozygous inactivation of human Ku70/Ku86 heterodimer does not affect cell growth, double-strand break repair, or genome integrity.

Uegaki K, Adachi N, So S, Iiizumi S, Koyama H.

DNA Repair (Amst). 2006 Mar 7;5(3):303-11. Epub 2005 Dec 1.

PMID:
16325483
9.

Ku86 represses lethal telomere deletion events in human somatic cells.

Wang Y, Ghosh G, Hendrickson EA.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12430-5. doi: 10.1073/pnas.0903362106. Epub 2009 Jul 6.

10.

The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons.

Vandersickel V, Mancini M, Slabbert J, Marras E, Thierens H, Perletti G, Vral A.

Radiat Oncol. 2010 Apr 27;5:30. doi: 10.1186/1748-717X-5-30.

11.
12.

Suppression of DNA-PKcs and Ku80 individually and in combination: Different effects of radiobiology in HeLa cells.

Zhuang L, Cao Y, Xiong H, Gao Q, Cao Z, Liu F, Qiu H, Yu S, Huang X.

Int J Oncol. 2011 Aug;39(2):443-51. doi: 10.3892/ijo.2011.1041. Epub 2011 May 13.

PMID:
21573502
13.

KARP-1 works as a heterodimer with Ku70, but the function of KARP-1 cannot perfectly replace that of Ku80 in DSB repair.

Koike M, Yutoku Y, Koike A.

Exp Cell Res. 2011 Oct 1;317(16):2267-75. doi: 10.1016/j.yexcr.2011.06.015. Epub 2011 Jul 2.

PMID:
21756904
14.

Oxidative stress induces nuclear loss of DNA repair proteins Ku70 and Ku80 and apoptosis in pancreatic acinar AR42J cells.

Song JY, Lim JW, Kim H, Morio T, Kim KH.

J Biol Chem. 2003 Sep 19;278(38):36676-87. Epub 2003 Jul 16.

15.
16.

Lentivirus-mediated RNA interference of Ku70 to enhance radiosensitivity of human mammary epithelial cells.

Vandersickel V, Mancini M, Marras E, Willems P, Slabbert J, Philippé J, Deschepper E, Thierens H, Perletti G, Vral A.

Int J Radiat Biol. 2010 Feb;86(2):114-24. doi: 10.3109/09553000903419940.

PMID:
20148697
17.
18.

DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining.

Douglas P, Gupta S, Morrice N, Meek K, Lees-Miller SP.

DNA Repair (Amst). 2005 Aug 15;4(9):1006-18.

PMID:
15941674
19.

Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants.

Errami A, Smider V, Rathmell WK, He DM, Hendrickson EA, Zdzienicka MZ, Chu G.

Mol Cell Biol. 1996 Apr;16(4):1519-26.

20.

Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo.

Li GC, He F, Shao X, Urano M, Shen L, Kim D, Borrelli M, Leibel SA, Gutin PH, Ling CC.

Cancer Res. 2003 Jun 15;63(12):3268-74.

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