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Items: 1 to 20 of 62

1.

Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.

Moody CA, Scott RS, Amirghahari N, Nathan CO, Young LS, Dawson CW, Sixbey JW.

J Virol. 2005 May;79(9):5499-506.

3.

Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.

Wang X, Yue P, Chan CB, Ye K, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Fu H, Khuri FR, Sun SY.

Mol Cell Biol. 2007 Nov;27(21):7405-13. Epub 2007 Aug 27.

4.

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.

Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N.

Genes Dev. 1998 Feb 15;12(4):502-13.

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A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.

Aoki M, Blazek E, Vogt PK.

Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):136-41.

8.

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.

Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.

J Biol Chem. 1998 Jun 5;273(23):14484-94. Erratum in: J Biol Chem 1998 Aug 21;273(34):22160.

9.

Determinants of rapamycin sensitivity in breast cancer cells.

Noh WC, Mondesire WH, Peng J, Jian W, Zhang H, Dong J, Mills GB, Hung MC, Meric-Bernstam F.

Clin Cancer Res. 2004 Feb 1;10(3):1013-23.

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11.

Epstein-Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-kappaB transcription factor pathway.

Stewart S, Dawson CW, Takada K, Curnow J, Moody CA, Sixbey JW, Young LS.

Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15730-5. Epub 2004 Oct 21.

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13.

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.

Oncogene. 2007 Aug 16;26(38):5606-14. Epub 2007 Mar 12.

PMID:
17353907
14.

Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.

Cen O, Longnecker R.

Mol Cancer Ther. 2011 Apr;10(4):679-86. doi: 10.1158/1535-7163.MCT-10-0833. Epub 2011 Jan 31.

15.

Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.

Khan N, Afaq F, Khusro FH, Mustafa Adhami V, Suh Y, Mukhtar H.

Int J Cancer. 2012 Apr 1;130(7):1695-705. doi: 10.1002/ijc.26178. Epub 2011 Aug 26.

16.

Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers.

Zhou X, Tan M, Stone Hawthorne V, Klos KS, Lan KH, Yang Y, Yang W, Smith TL, Shi D, Yu D.

Clin Cancer Res. 2004 Oct 15;10(20):6779-88.

18.

A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.

Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.

Cancer Res. 2000 Jul 1;60(13):3504-13.

19.

Mammalian target of rapamycin is activated in association with myometrial proliferation during pregnancy.

Jaffer S, Shynlova O, Lye S.

Endocrinology. 2009 Oct;150(10):4672-80. doi: 10.1210/en.2009-0419. Epub 2009 Jul 9.

PMID:
19589861
20.

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