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Items: 1 to 20 of 131

1.

High-throughput screens and selections of enzyme-encoding genes.

Aharoni A, Griffiths AD, Tawfik DS.

Curr Opin Chem Biol. 2005 Apr;9(2):210-6. Review.

PMID:
15811807
2.

Advances in laboratory evolution of enzymes.

Bershtein S, Tawfik DS.

Curr Opin Chem Biol. 2008 Apr;12(2):151-8. doi: 10.1016/j.cbpa.2008.01.027. Epub 2008 Mar 7. Review.

PMID:
18284924
3.

Ultrahigh-throughput FACS-based screening for directed enzyme evolution.

Yang G, Withers SG.

Chembiochem. 2009 Nov 23;10(17):2704-15. doi: 10.1002/cbic.200900384. Review.

PMID:
19780076
4.

Recent progress in biocatalyst discovery and optimization.

Robertson DE, Steer BA.

Curr Opin Chem Biol. 2004 Apr;8(2):141-9. Review.

PMID:
15062774
5.

Directed evolution of sulfotransferases and paraoxonases by ancestral libraries.

Alcolombri U, Elias M, Tawfik DS.

J Mol Biol. 2011 Aug 26;411(4):837-53. doi: 10.1016/j.jmb.2011.06.037. Epub 2011 Jun 24.

PMID:
21723874
6.

In vitro selection of restriction endonucleases by in vitro compartmentalization.

Doi N, Kumadaki S, Oishi Y, Matsumura N, Yanagawa H.

Nucleic Acids Res. 2004 Jul 6;32(12):e95.

7.

Random mutagenesis methods for in vitro directed enzyme evolution.

Labrou NE.

Curr Protein Pept Sci. 2010 Feb;11(1):91-100. Review.

PMID:
20201809
8.

In vitro enzyme evolution: the screening challenge of isolating the one in a million.

Cohen N, Abramov S, Dror Y, Freeman A.

Trends Biotechnol. 2001 Dec;19(12):507-10. Review.

PMID:
11711194
9.

Novel concepts for selection of catalytic activity.

Soumillion P, Fastrez J.

Curr Opin Biotechnol. 2001 Aug;12(4):387-94. Review.

PMID:
11551468
10.

High-throughput assays for lipases and esterases.

Schmidt M, Bornscheuer UT.

Biomol Eng. 2005 Jun;22(1-3):51-6. Review.

PMID:
15857783
11.

Directed evolution and the creation of enantioselective biocatalysts.

Jaeger KE, Eggert T, Eipper A, Reetz MT.

Appl Microbiol Biotechnol. 2001 May;55(5):519-30. Review.

PMID:
11414315
12.

High-throughput screening of enzyme libraries.

Olsen M, Iverson B, Georgiou G.

Curr Opin Biotechnol. 2000 Aug;11(4):331-7. Review.

PMID:
10975452
13.

Directed enzyme evolution: beyond the low-hanging fruit.

Goldsmith M, Tawfik DS.

Curr Opin Struct Biol. 2012 Aug;22(4):406-12. doi: 10.1016/j.sbi.2012.03.010. Epub 2012 May 12. Review.

PMID:
22579412
14.

Genotype-phenotype linkage for directed evolution and screening of combinatorial protein libraries.

Doi N, Yanagawa H.

Comb Chem High Throughput Screen. 2001 Sep;4(6):497-509. Review.

PMID:
11562254
15.

Micro-colony array based high throughput platform for enzyme library screening.

Pohn B, Gerlach J, Scheideler M, Katz H, Uray M, Bischof H, Klimant I, Schwab H.

J Biotechnol. 2007 Mar 30;129(1):162-70. Epub 2006 Nov 16.

PMID:
17174002
16.

Selection strategies for improved biocatalysts.

Boersma YL, Dröge MJ, Quax WJ.

FEBS J. 2007 May;274(9):2181-95. Review.

17.
18.

The quest for molecular quasi-species in ligand-activity space and its application to directed enzyme evolution.

Mannervik B, Runarsdottir A.

FEBS Lett. 2010 Jun 18;584(12):2565-71. doi: 10.1016/j.febslet.2010.04.024. Epub 2010 Apr 18. Review.

19.

Enzyme genomics: Application of general enzymatic screens to discover new enzymes.

Kuznetsova E, Proudfoot M, Sanders SA, Reinking J, Savchenko A, Arrowsmith CH, Edwards AM, Yakunin AF.

FEMS Microbiol Rev. 2005 Apr;29(2):263-79. Review.

20.

Engineered enzymes for chemical production.

Luetz S, Giver L, Lalonde J.

Biotechnol Bioeng. 2008 Nov 1;101(4):647-53. doi: 10.1002/bit.22077. Review.

PMID:
18814289

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