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Items: 1 to 20 of 116

1.

Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site.

Ali SM, Sabatini DM.

J Biol Chem. 2005 May 20;280(20):19445-8. Epub 2005 Apr 4.

2.

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.

Saitoh M, Pullen N, Brennan P, Cantrell D, Dennis PB, Thomas G.

J Biol Chem. 2002 May 31;277(22):20104-12. Epub 2002 Mar 25.

3.

Characterization of phosphatidylinositol 3-kinase-dependent phosphorylation of the hydrophobic motif site Thr(389) in p70 S6 kinase 1.

Romanelli A, Dreisbach VC, Blenis J.

J Biol Chem. 2002 Oct 25;277(43):40281-9. Epub 2002 Aug 14.

4.

Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.

Holz MK, Blenis J.

J Biol Chem. 2005 Jul 15;280(28):26089-93. Epub 2005 May 19.

5.

Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin.

Park IH, Bachmann R, Shirazi H, Chen J.

J Biol Chem. 2002 Aug 30;277(35):31423-9. Epub 2002 Jun 26.

6.

Rictor is a novel target of p70 S6 kinase-1.

Treins C, Warne PH, Magnuson MA, Pende M, Downward J.

Oncogene. 2010 Feb 18;29(7):1003-16. doi: 10.1038/onc.2009.401. Epub 2009 Nov 23.

PMID:
19935711
7.

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.

Liu L, Li F, Cardelli JA, Martin KA, Blenis J, Huang S.

Oncogene. 2006 Nov 9;25(53):7029-40. Epub 2006 May 22.

PMID:
16715128
8.

Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase.

Chrestensen CA, Sturgill TW.

J Biol Chem. 2002 Aug 2;277(31):27733-41. Epub 2002 May 16.

9.
10.

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro.

Isotani S, Hara K, Tokunaga C, Inoue H, Avruch J, Yonezawa K.

J Biol Chem. 1999 Nov 26;274(48):34493-8.

11.

Characterization of S6K2, a novel kinase homologous to S6K1.

Lee-Fruman KK, Kuo CJ, Lippincott J, Terada N, Blenis J.

Oncogene. 1999 Sep 9;18(36):5108-14.

12.

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.

Byfield MP, Murray JT, Backer JM.

J Biol Chem. 2005 Sep 23;280(38):33076-82. Epub 2005 Jul 27.

13.
14.

Raptor-rictor axis in TGFbeta-induced protein synthesis.

Das F, Ghosh-Choudhury N, Mahimainathan L, Venkatesan B, Feliers D, Riley DJ, Kasinath BS, Choudhury GG.

Cell Signal. 2008 Feb;20(2):409-23. Epub 2007 Nov 7.

PMID:
18068336
15.

AKT-independent phosphorylation of TSC2 and activation of mTOR and ribosomal protein S6 kinase signaling by prostaglandin F2alpha.

Arvisais EW, Romanelli A, Hou X, Davis JS.

J Biol Chem. 2006 Sep 15;281(37):26904-13. Epub 2006 Jul 1.

16.
17.

mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer.

Dann SG, Selvaraj A, Thomas G.

Trends Mol Med. 2007 Jun;13(6):252-9. Epub 2007 Apr 23. Review.

PMID:
17452018
19.

Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.

Park IH, Erbay E, Nuzzi P, Chen J.

Exp Cell Res. 2005 Sep 10;309(1):211-9.

PMID:
15963500
20.

mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD.

Mol Cell Biol. 2003 Dec;23(23):8862-77.

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