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Items: 1 to 20 of 462

1.

Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.

Stewart RS, Piccardo P, Ghetti B, Harris DA.

J Neurosci. 2005 Mar 30;25(13):3469-77.

2.

A transmembrane form of the prion protein is localized in the Golgi apparatus of neurons.

Stewart RS, Harris DA.

J Biol Chem. 2005 Apr 22;280(16):15855-64. Epub 2005 Jan 25.

3.

Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation.

Chiesa R, Pestronk A, Schmidt RE, Tourtellotte WG, Ghetti B, Piccardo P, Harris DA.

Neurobiol Dis. 2001 Apr;8(2):279-88.

PMID:
11300723
4.

A transmembrane form of the prion protein in neurodegenerative disease.

Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR.

Science. 1998 Feb 6;279(5352):827-34.

5.

Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

Chiesa R, Piccardo P, Ghetti B, Harris DA.

Neuron. 1998 Dec;21(6):1339-51.

6.

Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice.

Pfeifer A, Eigenbrod S, Al-Khadra S, Hofmann A, Mitteregger G, Moser M, Bertsch U, Kretzschmar H.

J Clin Invest. 2006 Dec;116(12):3204-10.

7.

A transgenic model of a familial prion disease.

Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B.

Arch Virol Suppl. 2000;(16):103-12. Review.

PMID:
11214912
8.

Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties.

Cancellotti E, Wiseman F, Tuzi NL, Baybutt H, Monaghan P, Aitchison L, Simpson J, Manson JC.

J Biol Chem. 2005 Dec 30;280(52):42909-18. Epub 2005 Oct 11.

9.

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C.

J Neurosci. 2005 Mar 16;25(11):2793-802.

10.

GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice.

Barmada S, Piccardo P, Yamaguchi K, Ghetti B, Harris DA.

Neurobiol Dis. 2004 Aug;16(3):527-37.

PMID:
15262264
11.

Cell surface accumulation of a truncated transmembrane prion protein in Gerstmann-Straussler-Scheinker disease P102L.

Mishra RS, Gu Y, Bose S, Verghese S, Kalepu S, Singh N.

J Biol Chem. 2002 Jul 5;277(27):24554-61. Epub 2002 Apr 19.

12.

Transmissible and genetic prion diseases share a common pathway of neurodegeneration.

Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR.

Nature. 1999 Dec 16;402(6763):822-6.

PMID:
10617204
13.

Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease.

Meier P, Genoud N, Prinz M, Maissen M, Rülicke T, Zurbriggen A, Raeber AJ, Aguzzi A.

Cell. 2003 Apr 4;113(1):49-60.

14.

Methionine sulfoxides on PrPSc: a prion-specific covalent signature.

Canello T, Engelstein R, Moshel O, Xanthopoulos K, Juanes ME, Langeveld J, Sklaviadis T, Gasset M, Gabizon R.

Biochemistry. 2008 Aug 26;47(34):8866-73. doi: 10.1021/bi800801f. Epub 2008 Aug 5.

PMID:
18680312
15.

The neuropathological phenotype in transgenic mice expressing different prion protein constructs.

DeArmond SJ, Yang SL, Cayetano-Canlas J, Groth D, Prusiner SB.

Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29;343(1306):415-23. Review.

PMID:
7913760
16.

Transgenetic investigations of prion diseases of humans and animals.

Prusiner SB.

Philos Trans R Soc Lond B Biol Sci. 1993 Feb 27;339(1288):239-54. Review.

PMID:
8097053
17.

Cellular prion protein co-localizes with nAChR beta4 subunit in brain and gastrointestinal tract.

Petrakis S, Irinopoulou T, Panagiotidis CH, Engelstein R, Lindstrom J, Orr-Urtreger A, Gabizon R, Grigoriadis N, Sklaviadis T.

Eur J Neurosci. 2008 Feb;27(3):612-20. doi: 10.1111/j.1460-9568.2008.06037.x. Erratum in: Eur J Neurosci. 2008 Apr;27(8):2212.

PMID:
18279314
18.

The scrapie prion protein is present in flotillin-1-positive vesicles in central- but not peripheral-derived neuronal cell lines.

Pimpinelli F, Lehmann S, Maridonneau-Parini I.

Eur J Neurosci. 2005 Apr;21(8):2063-72.

PMID:
15869502
19.

Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only.

Crozet C, Lezmi S, Flamant F, Samarut J, Baron T, Bencsik A.

J Infect Dis. 2007 Apr 1;195(7):997-1006. Epub 2007 Feb 16.

PMID:
17330790
20.

Scrg1 is induced in TSE and brain injuries, and associated with autophagy.

Dron M, Bailly Y, Beringue V, Haeberlé AM, Griffond B, Risold PY, Tovey MG, Laude H, Dandoy-Dron F.

Eur J Neurosci. 2005 Jul;22(1):133-46.

PMID:
16029203

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