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Items: 1 to 20 of 103

1.

Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.

Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V, Dina C, Hamid YH, Joly E, Vaillant E, Benmezroua Y, Durand E, Bakaher N, Delannoy V, Vaxillaire M, Cook T, Dallinga-Thie GM, Jansen H, Charles MA, Clément K, Galan P, Hercberg S, Helbecque N, Charpentier G, Prentki M, Hansen T, Pedersen O, Urrutia R, Melloul D, Froguel P.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4807-12. Epub 2005 Mar 17.

2.

Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.

Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R.

J Biol Chem. 2013 Jun 14;288(24):17745-58. doi: 10.1074/jbc.M112.434670. Epub 2013 Apr 15.

3.

Identification of minimal promoter and genetic variants of Kruppel-like factor 11 gene and association analysis with type 2 diabetes in Japanese.

Kuroda E, Horikawa Y, Enya M, Oda N, Suzuki E, Iizuka K, Takeda J.

Endocr J. 2009;56(2):275-86. Epub 2008 Dec 27.

4.

Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C.

Gutiérrez-Aguilar R, Froguel P, Hamid YH, Benmezroua Y, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O, Neve B.

J Clin Endocrinol Metab. 2008 Aug;93(8):3128-35. doi: 10.1210/jc.2007-2504. Epub 2008 May 27.

PMID:
18505768
5.

MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells.

Fernandez-Zapico ME, van Velkinburgh JC, Gutiérrez-Aguilar R, Neve B, Froguel P, Urrutia R, Stein R.

J Biol Chem. 2009 Dec 25;284(52):36482-90. doi: 10.1074/jbc.M109.028852. Epub 2009 Oct 20.

6.

Human Krüppel-like factor 11 inhibits human proinsulin promoter activity in pancreatic beta cells.

Niu X, Perakakis N, Laubner K, Limbert C, Stahl T, Brendel MD, Bretzel RG, Seufert J, Päth G.

Diabetologia. 2007 Jul;50(7):1433-41. Epub 2007 May 4. Erratum in: Diabetologia. 2007 Sep;50(9):2031. Diabetologia. 2007 Sep;50(9):2031.

PMID:
17479246
7.
8.

KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells.

Ellenrieder V, Buck A, Harth A, Jungert K, Buchholz M, Adler G, Urrutia R, Gress TM.

Gastroenterology. 2004 Aug;127(2):607-20.

PMID:
15300592
9.

The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.

Florez JC, Saxena R, Winckler W, Burtt NP, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Ardlie KG, Daly MJ, Altshuler D, Hirschhorn JN, Groop L.

Diabetes. 2006 Dec;55(12):3620-4.

10.

The association of genetic variants in Krüppel-like factor 11 and Type 2 diabetes in the Japanese population.

Tanahashi T, Shinohara K, Keshavarz P, Yamaguchi Y, Miyawaki K, Kunika K, Moritani M, Nakamura N, Yoshikawa T, Shiota H, Inoue H, Itakura M.

Diabet Med. 2008 Jan;25(1):19-26. doi: 10.1111/j.1464-5491.2007.02315.x.

11.

Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells.

Yin P, Lin Z, Reierstad S, Wu J, Ishikawa H, Marsh EE, Innes J, Cheng Y, Pearson K, Coon JS 5th, Kim JJ, Chakravarti D, Bulun SE.

Cancer Res. 2010 Feb 15;70(4):1722-30. doi: 10.1158/0008-5472.CAN-09-2612. Epub 2010 Feb 2.

12.

Krüppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-κB signaling pathway.

Fan Y, Guo Y, Zhang J, Subramaniam M, Song CZ, Urrutia R, Chen YE.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2981-8. doi: 10.1161/ATVBAHA.112.300349. Epub 2012 Oct 4.

13.

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians.

Ma L, Hanson RL, Que LN, Mack JL, Franks PW, Infante AM, Kobes S, Bogardus C, Baier LJ.

J Clin Endocrinol Metab. 2008 Sep;93(9):3644-9. doi: 10.1210/jc.2008-0546. Epub 2008 Jul 1.

14.

Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines.

Martin D, Tawadros T, Meylan L, Abderrahmani A, Condorelli DF, Waeber G, Haefliger JA.

J Biol Chem. 2003 Dec 26;278(52):53082-9. Epub 2003 Oct 16.

15.

Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes.

Mathison A, Escande C, Calvo E, Seo S, White T, Salmonson A, Faubion WA Jr, Buttar N, Iovanna J, Lomberk G, Chini EN, Urrutia R.

Endocrinology. 2015 Oct;156(10):3581-95. doi: 10.1210/en.2015-1145. Epub 2015 Aug 6.

16.

KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling.

Cao S, Fernandez-Zapico ME, Jin D, Puri V, Cook TA, Lerman LO, Zhu XY, Urrutia R, Shah V.

J Biol Chem. 2005 Jan 21;280(3):1901-10. Epub 2004 Nov 5.

17.

Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus.

Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, Cavé H, Iovanna J, Stein R, Polak M, Vaxillaire M, Froguel P, Urrutia R.

J Biol Chem. 2011 Aug 12;286(32):28414-24. doi: 10.1074/jbc.M110.215822. Epub 2011 May 18.

18.

The bile acid sensor FXR regulates insulin transcription and secretion.

Renga B, Mencarelli A, Vavassori P, Brancaleone V, Fiorucci S.

Biochim Biophys Acta. 2010 Mar;1802(3):363-72. doi: 10.1016/j.bbadis.2010.01.002. Epub 2010 Jan 7.

19.

An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation.

Fernandez-Zapico ME, Mladek A, Ellenrieder V, Folch-Puy E, Miller L, Urrutia R.

EMBO J. 2003 Sep 15;22(18):4748-58.

20.

Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression.

Grunewald M, Johnson S, Lu D, Wang Z, Lomberk G, Albert PR, Stockmeier CA, Meyer JH, Urrutia R, Miczek KA, Austin MC, Wang J, Paul IA, Woolverton WL, Seo S, Sittman DB, Ou XM.

J Biol Chem. 2012 Jul 13;287(29):24195-206. doi: 10.1074/jbc.M112.373936. Epub 2012 May 24.

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