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Items: 1 to 20 of 227

1.

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.

Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS.

Cell. 2005 Mar 11;120(5):701-13.

2.

Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.

van Groen T, Kiliaan AJ, Kadish I.

Neurobiol Dis. 2006 Sep;23(3):653-62. Epub 2006 Jul 10.

PMID:
16829076
3.

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.

Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard NP, Gerard C, Fraser P, Westaway D, St George-Hyslop P, Saido TC.

Neurosci Res. 2002 May;43(1):39-56.

PMID:
12074840
4.
5.

Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin).

Choi SH, Leight SN, Lee VM, Li T, Wong PC, Johnson JA, Saraiva MJ, Sisodia SS.

J Neurosci. 2007 Jun 27;27(26):7006-10.

6.

beta-amyloid deposits in transgenic mice expressing human beta-amyloid precursor protein have the same characteristics as those in Alzheimer's disease.

Terai K, Iwai A, Kawabata S, Tasaki Y, Watanabe T, Miyata K, Yamaguchi T.

Neuroscience. 2001;104(2):299-310.

PMID:
11377835
7.

GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.

Tian J, Shi J, Zhang L, Yin J, Hu Q, Xu Y, Sheng S, Wang P, Ren Y, Wang R, Wang Y.

Curr Alzheimer Res. 2009 Apr;6(2):118-31.

PMID:
19355846
8.

Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.

Howlett DR, Richardson JC, Austin A, Parsons AA, Bate ST, Davies DC, Gonzalez MI.

Brain Res. 2004 Aug 13;1017(1-2):130-6.

PMID:
15261108
9.

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

Wirths O, Multhaup G, Czech C, Blanchard V, Moussaoui S, Tremp G, Pradier L, Beyreuther K, Bayer TA.

Neurosci Lett. 2001 Jun 22;306(1-2):116-20.

PMID:
11403971
10.

Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.

Vepsäläinen S, Hiltunen M, Helisalmi S, Wang J, van Groen T, Tanila H, Soininen H.

Neurosci Lett. 2008 Jun 20;438(2):216-20. doi: 10.1016/j.neulet.2008.04.025. Epub 2008 Apr 12.

PMID:
18455870
11.

Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice.

Park IH, Hwang EM, Hong HS, Boo JH, Oh SS, Lee J, Jung MW, Bang OY, Kim SU, Mook-Jung I.

Neurobiol Aging. 2003 Sep;24(5):637-43.

PMID:
12885571
12.

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

Hemming ML, Patterson M, Reske-Nielsen C, Lin L, Isacson O, Selkoe DJ.

PLoS Med. 2007 Aug;4(8):e262.

13.
14.

Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice.

Wang J, Tanila H, Puoliväli J, Kadish I, van Groen T.

Neurobiol Dis. 2003 Dec;14(3):318-27. Erratum in: Neurobiol Dis. 2004 Jun;16(1):following 289.

PMID:
14678749
15.

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ.

Neuron. 2003 Dec 18;40(6):1087-93.

16.
17.

APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.

Kalback W, Watson MD, Kokjohn TA, Kuo YM, Weiss N, Luehrs DC, Lopez J, Brune D, Sisodia SS, Staufenbiel M, Emmerling M, Roher AE.

Biochemistry. 2002 Jan 22;41(3):922-8.

PMID:
11790115
18.

Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms.

Costa DA, Cracchiolo JR, Bachstetter AD, Hughes TF, Bales KR, Paul SM, Mervis RF, Arendash GW, Potter H.

Neurobiol Aging. 2007 Jun;28(6):831-44. Epub 2006 May 26.

PMID:
16730391
19.

Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.

Sadowski M, Pankiewicz J, Scholtzova H, Ji Y, Quartermain D, Jensen CH, Duff K, Nixon RA, Gruen RJ, Wisniewski T.

J Neuropathol Exp Neurol. 2004 May;63(5):418-28.

PMID:
15198121
20.

Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain.

Bürger S, Noack M, Kirazov LP, Kirazov EP, Naydenov CL, Kouznetsova E, Yafai Y, Schliebs R.

Int J Dev Neurosci. 2009 Oct;27(6):517-23. doi: 10.1016/j.ijdevneu.2009.06.011. Epub 2009 Jul 7.

PMID:
19589380

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