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Items: 1 to 20 of 93

1.

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells.

Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC, Podolsky DK.

J Biol Chem. 2005 May 13;280(19):19021-6. Epub 2005 Mar 7.

2.

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

Voss E, Wehkamp J, Wehkamp K, Stange EF, Schröder JM, Harder J.

J Biol Chem. 2006 Jan 27;281(4):2005-11. Epub 2005 Nov 30.

3.
4.

Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation.

Yamamoto-Furusho JK, Barnich N, Xavier R, Hisamatsu T, Podolsky DK.

J Biol Chem. 2006 Nov 24;281(47):36060-70. Epub 2006 Sep 27.

5.

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae.

Opitz B, Püschel A, Schmeck B, Hocke AC, Rosseau S, Hammerschmidt S, Schumann RR, Suttorp N, Hippenstiel S.

J Biol Chem. 2004 Aug 27;279(35):36426-32. Epub 2004 Jun 23.

6.

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells.

Hisamatsu T, Suzuki M, Reinecker HC, Nadeau WJ, McCormick BA, Podolsky DK.

Gastroenterology. 2003 Apr;124(4):993-1000.

PMID:
12671896
7.
8.

Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells.

Weichart D, Gobom J, Klopfleisch S, Häsler R, Gustavsson N, Billmann S, Lehrach H, Seegert D, Schreiber S, Rosenstiel P.

J Biol Chem. 2006 Jan 27;281(4):2380-9. Epub 2005 Oct 28.

9.

RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.

Lipinski S, Grabe N, Jacobs G, Billmann-Born S, Till A, Häsler R, Aden K, Paulsen M, Arlt A, Kraemer L, Hagemann N, Erdmann KS, Schreiber S, Rosenstiel P.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21426-31. doi: 10.1073/pnas.1209673109. Epub 2012 Dec 3.

10.

A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion.

Till A, Rosenstiel P, Bräutigam K, Sina C, Jacobs G, Oberg HH, Seegert D, Chakraborty T, Schreiber S.

J Cell Sci. 2008 Feb 15;121(Pt 4):487-95. doi: 10.1242/jcs.016980.

11.

A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling.

McDonald C, Chen FF, Ollendorff V, Ogura Y, Marchetto S, Lécine P, Borg JP, Nuñez G.

J Biol Chem. 2005 Dec 2;280(48):40301-9. Epub 2005 Oct 3.

12.

Regulation of Salmonella flagellin-induced interleukin-8 in intestinal epithelial cells by muramyl dipeptide.

Huang FC.

Cell Immunol. 2012 Jul-Aug;278(1-2):1-9. doi: 10.1016/j.cellimm.2012.06.013. Epub 2012 Jul 14.

PMID:
23121969
13.

The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process.

Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer TA, Habraken Y, Sadzot C, Louis E, Delvenne P, Piette J, Legrand-Poels S.

J Biol Chem. 2012 Aug 24;287(35):29213-26. doi: 10.1074/jbc.M112.355545. Epub 2012 Jun 14.

14.

The nucleotide synthesis enzyme CAD inhibits NOD2 antibacterial function in human intestinal epithelial cells.

Richmond AL, Kabi A, Homer CR, Marina-García N, Nickerson KP, Nesvizhskii AI, Sreekumar A, Chinnaiyan AM, Nuñez G, McDonald C.

Gastroenterology. 2012 Jun;142(7):1483-92.e6. doi: 10.1053/j.gastro.2012.02.040. Epub 2012 Feb 28.

15.

Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton.

Legrand-Poels S, Kustermans G, Bex F, Kremmer E, Kufer TA, Piette J.

J Cell Sci. 2007 Apr 1;120(Pt 7):1299-310. Epub 2007 Mar 13.

16.
17.

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.

Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3280-5. Epub 2006 Feb 21.

18.

Activation of NOD2-mediated intestinal pathway in a pediatric population with Crohn's disease.

Negroni A, Stronati L, Pierdomenico M, Tirindelli D, Di Nardo G, Mancini V, Maiella G, Cucchiara S.

Inflamm Bowel Dis. 2009 Aug;15(8):1145-54. doi: 10.1002/ibd.20907.

PMID:
19266573
19.

Activation of the nucleotide oligomerization domain signaling pathway by the non-bacterially derived xanthone drug 5'6-dimethylxanthenone-4-acetic acid (Vadimezan).

Cheng G, Sun J, Fridlender ZG, Wang LC, Ching LM, Albelda SM.

J Biol Chem. 2010 Apr 2;285(14):10553-62. doi: 10.1074/jbc.M109.065631. Epub 2010 Jan 29.

20.

Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll-like receptors, NOD1 and NOD2 in human oral epithelial cells.

Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Satta Y, Sasano T, Sugawara S, Takada H.

Cell Microbiol. 2005 May;7(5):675-86.

PMID:
15839897

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