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Items: 1 to 20 of 103


Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger.

Hochbaum D, Tanos T, Ribeiro-Neto F, Altschuler D, Coso OA.

J Biol Chem. 2003 Sep 5;278(36):33738-46. Epub 2003 Jun 3.


EphrinB1 interacts with CNK1 and promotes cell migration through c-Jun N-terminal kinase (JNK) activation.

Cho HJ, Hwang YS, Mood K, Ji YJ, Lim J, Morrison DK, Daar IO.

J Biol Chem. 2014 Jun 27;289(26):18556-68. doi: 10.1074/jbc.M114.558809. Epub 2014 May 13.


Galpha13 regulation of proto-Dbl signaling.

Vanni C, Mancini P, Ottaviano C, Ognibene M, Parodi A, Merello E, Russo C, Varesio L, Zheng Y, Torrisi MR, Eva A.

Cell Cycle. 2007 Aug 15;6(16):2058-70. Epub 2007 Jun 8.


Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement.

Holinstat M, Mehta D, Kozasa T, Minshall RD, Malik AB.

J Biol Chem. 2003 Aug 1;278(31):28793-8. Epub 2003 May 16.


The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.

Lim J, Zhou M, Veenstra TD, Morrison DK.

Genes Dev. 2010 Jul 15;24(14):1496-506. doi: 10.1101/gad.1904610.


Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II.

Ohtsu H, Mifune M, Frank GD, Saito S, Inagami T, Kim-Mitsuyama S, Takuwa Y, Sasaki T, Rothstein JD, Suzuki H, Nakashima H, Woolfolk EA, Motley ED, Eguchi S.

Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1831-6. Epub 2005 Jun 30.


Scaffold proteins dictate Rho GTPase-signaling specificity.

Marinissen MJ, Gutkind JS.

Trends Biochem Sci. 2005 Aug;30(8):423-6.


Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.

Zhou K, Wang Y, Gorski JL, Nomura N, Collard J, Bokoch GM.

J Biol Chem. 1998 Jul 3;273(27):16782-6.


Coupling receptor tyrosine kinases to Rho GTPases--GEFs what's the link.

Schiller MR.

Cell Signal. 2006 Nov;18(11):1834-43. Epub 2006 May 24. Review.


Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons.

Centeno C, Repici M, Chatton JY, Riederer BM, Bonny C, Nicod P, Price M, Clarke PG, Papa S, Franzoso G, Borsello T.

Cell Death Differ. 2007 Feb;14(2):240-53. Epub 2006 Jun 23.


Mixed-lineage kinase 3 deficiency promotes neointima formation through increased activation of the RhoA pathway in vascular smooth muscle cells.

Gadang V, Konaniah E, Hui DY, Jaeschke A.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1429-36. doi: 10.1161/ATVBAHA.114.303439. Epub 2014 May 1.


PAK1 negatively regulates the activity of the Rho exchange factor NET1.

Alberts AS, Qin H, Carr HS, Frost JA.

J Biol Chem. 2005 Apr 1;280(13):12152-61. Epub 2005 Jan 31.


G(i)-dependent activation of c-Jun N-terminal kinase in human embryonal kidney 293 cells.

Yamauchi J, Kawano T, Nagao M, Kaziro Y, Itoh H.

J Biol Chem. 2000 Mar 17;275(11):7633-40.


Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.

Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y.

J Biol Chem. 2004 Jan 30;279(5):3777-86. Epub 2003 Nov 3.


Signal transduction pathways regulated by arsenate and arsenite.

Porter AC, Fanger GR, Vaillancourt RR.

Oncogene. 1999 Dec 16;18(54):7794-802.


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