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Items: 1 to 20 of 329

1.

Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosis.

Dequiedt F, Van Lint J, Lecomte E, Van Duppen V, Seufferlein T, Vandenheede JR, Wattiez R, Kettmann R.

J Exp Med. 2005 Mar 7;201(5):793-804. Epub 2005 Feb 28.

2.

Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.

Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E.

J Biol Chem. 2005 Apr 8;280(14):13762-70. Epub 2004 Dec 28.

3.

HDAC7 regulates apoptosis in developing thymocytes.

Verdin E, Dequiedt F, Kasler H.

Novartis Found Symp. 2004;259:115-29; discussion 129-31, 163-9. Review.

PMID:
15171250
4.

ERK5 is involved in TCR-induced apoptosis through the modification of Nur77.

Fujii Y, Matsuda S, Takayama G, Koyasu S.

Genes Cells. 2008 May;13(5):411-9. doi: 10.1111/j.1365-2443.2008.01177.x.

5.
6.

Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis.

Woronicz JD, Lina A, Calnan BJ, Szychowski S, Cheng L, Winoto A.

Mol Cell Biol. 1995 Nov;15(11):6364-76.

7.

Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.

von Blume J, Knippschild U, Dequiedt F, Giamas G, Beck A, Auer A, Van Lint J, Adler G, Seufferlein T.

EMBO J. 2007 Nov 14;26(22):4619-33. Epub 2007 Oct 25.

8.

Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.

Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E.

J Immunol. 2011 Apr 15;186(8):4782-93. doi: 10.4049/jimmunol.1001179. Epub 2011 Mar 11.

10.

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis.

Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E.

Immunity. 2003 May;18(5):687-98.

11.

Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77-based mechanism.

Chen J, Fiskus W, Eaton K, Fernandez P, Wang Y, Rao R, Lee P, Joshi R, Yang Y, Kolhe R, Balusu R, Chappa P, Natarajan K, Jillella A, Atadja P, Bhalla KN.

Blood. 2009 Apr 23;113(17):4038-48. doi: 10.1182/blood-2008-08-176024. Epub 2008 Dec 12.

12.

Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation.

Cunningham NR, Artim SC, Fornadel CM, Sellars MC, Edmonson SG, Scott G, Albino F, Mathur A, Punt JA.

J Immunol. 2006 Nov 15;177(10):6660-6.

13.
14.

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA.

Nature. 1994 Jan 20;367(6460):281-4.

PMID:
8121494
15.

Orphan nuclear receptor Nur77 induces zinc finger protein GIOT-1 gene expression, and GIOT-1 acts as a novel corepressor of orphan nuclear receptor SF-1 via recruitment of HDAC2.

Song KH, Park YY, Kee HJ, Hong CY, Lee YS, Ahn SW, Kim HJ, Lee K, Kook H, Lee IK, Choi HS.

J Biol Chem. 2006 Jun 9;281(23):15605-14. Epub 2006 Apr 4.

16.

Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7.

Kao HY, Verdel A, Tsai CC, Simon C, Juguilon H, Khochbin S.

J Biol Chem. 2001 Dec 14;276(50):47496-507. Epub 2001 Oct 3.

17.

Molecular characterization of the Nur77 orphan steroid receptor in apoptosis.

Winoto A.

Int Arch Allergy Immunol. 1994 Dec;105(4):344-6. Review.

PMID:
7981602
18.

Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis.

Masuyama N, Oishi K, Mori Y, Ueno T, Takahama Y, Gotoh Y.

J Biol Chem. 2001 Aug 31;276(35):32799-805. Epub 2001 Jul 3.

19.

A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

Dressel U, Bailey PJ, Wang SC, Downes M, Evans RM, Muscat GE.

J Biol Chem. 2001 May 18;276(20):17007-13. Epub 2001 Mar 8.

20.

Nur77 regulates lipolysis in skeletal muscle cells. Evidence for cross-talk between the beta-adrenergic and an orphan nuclear hormone receptor pathway.

Maxwell MA, Cleasby ME, Harding A, Stark A, Cooney GJ, Muscat GE.

J Biol Chem. 2005 Apr 1;280(13):12573-84. Epub 2005 Jan 6.

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