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Items: 1 to 20 of 88

1.

Thymidine phosphorylase (platelet-derived endothelial-cell growth factor) in cancer biology and treatment.

Toi M, Atiqur Rahman M, Bando H, Chow LW.

Lancet Oncol. 2005 Mar;6(3):158-66. Review.

PMID:
15737832
2.

Targeting platelet-derived endothelial cell growth factor/thymidine phosphorylase for cancer therapy.

Liekens S, Bronckaers A, Pérez-Pérez MJ, Balzarini J.

Biochem Pharmacol. 2007 Dec 3;74(11):1555-67. Epub 2007 May 16. Review.

PMID:
17572389
3.

Thymidine phosphorylase (platelet-derived endothelial cell growth factor) as a target for capecitabine: from biology to the bedside.

Ranieri G, Roccaro AM, Vacca A, Ribatti D.

Recent Pat Anticancer Drug Discov. 2006 Jun;1(2):171-83. Review.

PMID:
18221035
4.

Thymidine phosphorylase-mediated angiogenesis regulated by thymidine phosphorylase inhibitor in human ovarian cancer cells in vivo.

Tsukagoshi S, Saga Y, Suzuki N, Fujioka A, Nakagawa F, Fukushima M, Suzuki M.

Int J Oncol. 2003 May;22(5):961-7.

PMID:
12684660
5.

The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium.

Fox SB, Westwood M, Moghaddam A, Comley M, Turley H, Whitehouse RM, Bicknell R, Gatter KC, Harris AL.

Br J Cancer. 1996 Feb;73(3):275-80.

6.

Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer.

Bera H, Chigurupati S.

Eur J Med Chem. 2016 Nov 29;124:992-1003. doi: 10.1016/j.ejmech.2016.10.032. Epub 2016 Oct 17. Review.

PMID:
27783978
7.
8.

Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy.

Koukourakis MI, Giatromanolaki A, Fountzilas G, Sivridis E, Gatter KC, Harris AL.

Clin Cancer Res. 2000 Feb;6(2):381-9.

9.

The role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumor behavior.

Bijnsdorp IV, de Bruin M, Laan AC, Fukushima M, Peters GJ.

Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):681-91. doi: 10.1080/15257770802143988. Review.

PMID:
18600526
10.

The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.

Akiyama S, Furukawa T, Sumizawa T, Takebayashi Y, Nakajima Y, Shimaoka S, Haraguchi M.

Cancer Sci. 2004 Nov;95(11):851-7. Review.

11.

The dual role of thymidine phosphorylase in cancer development and chemotherapy.

Bronckaers A, Gago F, Balzarini J, Liekens S.

Med Res Rev. 2009 Nov;29(6):903-53. doi: 10.1002/med.20159. Review.

PMID:
19434693
12.

Prognostic role of thymidylate synthase, thymidine phosphorylase/platelet-derived endothelial cell growth factor, and proliferation markers in colorectal cancer.

van Triest B, Pinedo HM, Blaauwgeers JL, van Diest PJ, Schoenmakers PS, Voorn DA, Smid K, Hoekman K, Hoitsma HF, Peters GJ.

Clin Cancer Res. 2000 Mar;6(3):1063-72.

13.

Thymidine phosphorylase: a two-face Janus in anticancer chemotherapy.

Focher F, Spadari S.

Curr Cancer Drug Targets. 2001 Aug;1(2):141-53. Review.

PMID:
12188887
15.

Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy.

Gasparini G, Toi M, Miceli R, Vermeulen PB, Dittadi R, Biganzoli E, Morabito A, Fanelli M, Gatti C, Suzuki H, Tominaga T, Dirix LY, Gion M.

Cancer J Sci Am. 1999 Mar-Apr;5(2):101-11.

PMID:
10198732
16.

Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis.

Focher F, Ubiali D, Pregnolato M, Zhi C, Gambino J, Wright GE, Spadari S.

J Med Chem. 2000 Jun 29;43(13):2601-7.

PMID:
10891120
17.

2-Deoxy-D-ribose, a downstream mediator of thymidine phosphorylase, regulates tumor angiogenesis and progression.

Nakajima Y, Madhyastha R, Maruyama M.

Anticancer Agents Med Chem. 2009 Feb;9(2):239-45. Review.

PMID:
19199868
18.

Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.

Uchimiya H, Furukawa T, Okamoto M, Nakajima Y, Matsushita S, Ikeda R, Gotanda T, Haraguchi M, Sumizawa T, Ono M, Kuwano M, Kanzaki T, Akiyama S.

Cancer Res. 2002 May 15;62(10):2834-9.

19.

The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers.

Gunningham SP, Currie MJ, Morrin HR, Tan EY, Turley H, Dachs GU, Watson AI, Frampton C, Robinson BA, Fox SB.

J Pathol. 2007 Jul;212(3):335-44.

PMID:
17487938
20.

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