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Items: 1 to 20 of 174

1.

Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

Liu S, Shen T, Huynh L, Klisovic MI, Rush LJ, Ford JL, Yu J, Becknell B, Li Y, Liu C, Vukosavljevic T, Whitman SP, Chang KS, Byrd JC, Perrotti D, Plass C, Marcucci G.

Cancer Res. 2005 Feb 15;65(4):1277-84.

2.
3.

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.

Klisovic MI, Maghraby EA, Parthun MR, Guimond M, Sklenar AR, Whitman SP, Chan KK, Murphy T, Anon J, Archer KJ, Rush LJ, Plass C, Grever MR, Byrd JC, Marcucci G.

Leukemia. 2003 Feb;17(2):350-8.

PMID:
12592335
4.

MYND-less splice variants of AML1-MTG8 (RUNX1-CBFA2T1) are expressed in leukemia with t(8;21).

Kozu T, Fukuyama T, Yamami T, Akagi K, Kaneko Y.

Genes Chromosomes Cancer. 2005 May;43(1):45-53.

PMID:
15723339
5.

Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia.

Ter Elst A, Ma B, Scherpen FJ, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES.

Cancer Res. 2011 Apr 1;71(7):2761-71. doi: 10.1158/0008-5472.CAN-10-0402. Epub 2011 Mar 29.

6.

Mechanism of transcriptional repression by TEL/RUNX1 fusion protein.

Lee YJ, Kim JH, Bae S, Rho SK, Choe SY.

Mol Cells. 2004 Apr 30;17(2):217-22.

7.

Discrimination of target by siRNA: designing of AML1-MTG8 fusion mRNA-specific siRNA sequences.

Kasashima K, Sakota E, Kozu T.

Biochimie. 2004 Sep-Oct;86(9-10):713-21.

PMID:
15556282
8.

AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells.

Heidenreich O, Krauter J, Riehle H, Hadwiger P, John M, Heil G, Vornlocher HP, Nordheim A.

Blood. 2003 Apr 15;101(8):3157-63. Epub 2002 Dec 12.

9.

Role of RUNX family members in transcriptional repression and gene silencing.

Durst KL, Hiebert SW.

Oncogene. 2004 May 24;23(24):4220-4. Review.

PMID:
15156176
10.

siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.

Dunne J, Cullmann C, Ritter M, Soria NM, Drescher B, Debernardi S, Skoulakis S, Hartmann O, Krause M, Krauter J, Neubauer A, Young BD, Heidenreich O.

Oncogene. 2006 Oct 5;25(45):6067-78. Epub 2006 May 1.

PMID:
16652140
11.

The role of a Runt domain transcription factor AML1/RUNX1 in leukemogenesis and its clinical implications.

Asou N.

Crit Rev Oncol Hematol. 2003 Feb;45(2):129-50. Review. Erratum in: Crit Rev Oncol Hematol. 2006 Oct;60(1):87.

PMID:
12604126
12.

Runx1 promotes angiogenesis by downregulation of insulin-like growth factor-binding protein-3.

Iwatsuki K, Tanaka K, Kaneko T, Kazama R, Okamoto S, Nakayama Y, Ito Y, Satake M, Takahashi S, Miyajima A, Watanabe T, Hara T.

Oncogene. 2005 Feb 10;24(7):1129-37.

PMID:
15592512
14.

Induction of apoptosis in myeloid leukaemic cells by ribozymes targeted against AML1/MTG8.

Matsushita H, Kizaki M, Kobayashi H, Muto A, Ikeda Y.

Br J Cancer. 1999 Mar;79(9-10):1325-31.

15.

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6948-53. Epub 2005 May 3.

17.

Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation.

Lutterbach B, Hiebert SW.

Gene. 2000 Mar 21;245(2):223-35. Review.

PMID:
10717473
18.

A distinct epigenetic signature at targets of a leukemia protein.

Rossetti S, Hoogeveen AT, Liang P, Stanciu C, van der Spek P, Sacchi N.

BMC Genomics. 2007 Feb 1;8:38.

19.

Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice.

Yanagida M, Osato M, Yamashita N, Liqun H, Jacob B, Wu F, Cao X, Nakamura T, Yokomizo T, Takahashi S, Yamamoto M, Shigesada K, Ito Y.

Oncogene. 2005 Jun 30;24(28):4477-85.

PMID:
15856017
20.

The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells.

Martinez N, Drescher B, Riehle H, Cullmann C, Vornlocher HP, Ganser A, Heil G, Nordheim A, Krauter J, Heidenreich O.

BMC Cancer. 2004 Aug 6;4:44.

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