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Items: 1 to 20 of 94

1.

p53--a key player in tumoral and evolutionary adaptation: a lesson from the Israeli blind subterranean mole rat.

Avivi A, Ashur-Fabian O, Amariglio N, Nevo E, Rechavi G.

Cell Cycle. 2005 Mar;4(3):368-72. Epub 2005 Mar 11. Review.

PMID:
15701965
2.

P53 in blind subterranean mole rats--loss-of-function versus gain-of-function activities on newly cloned Spalax target genes.

Avivi A, Ashur-Fabian O, Joel A, Trakhtenbrot L, Adamsky K, Goldstein I, Amariglio N, Rechavi G, Nevo E.

Oncogene. 2007 Apr 12;26(17):2507-12. Epub 2006 Oct 16.

PMID:
17043642
3.

Transcription pattern of p53-targeted DNA repair genes in the hypoxia-tolerant subterranean mole rat Spalax.

Shams I, Malik A, Manov I, Joel A, Band M, Avivi A.

J Mol Biol. 2013 Apr 12;425(7):1111-8. doi: 10.1016/j.jmb.2013.01.007. Epub 2013 Jan 11.

PMID:
23318952
4.

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation.

Ashur-Fabian O, Avivi A, Trakhtenbrot L, Adamsky K, Cohen M, Kajakaro G, Joel A, Amariglio N, Nevo E, Rechavi G.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12236-41. Epub 2004 Aug 9.

5.

Cellular adaptation to hypoxia and p53 transcription regulation.

Zhao Y, Chen XQ, Du JZ.

J Zhejiang Univ Sci B. 2009 May;10(5):404-10. doi: 10.1631/jzus.B0820293. Review.

6.

Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax.

Domankevich V, Opatowsky Y, Malik A, Korol AB, Frenkel Z, Manov I, Avivi A, Shams I.

BMC Evol Biol. 2016 Sep 2;16:177. doi: 10.1186/s12862-016-0743-8.

7.

The expression of p53-target genes in the hypoxia-tolerant subterranean mole-rat is hypoxia-dependent and similar to expression patterns in solid tumors.

Band M, Ashur-Fabian O, Avivi A.

Cell Cycle. 2010 Aug 15;9(16):3347-52. doi: 10.4161/cc.9.16.12712. Epub 2010 Aug 17.

PMID:
20703075
8.

Living with stress: regulation of antioxidant defense genes in the subterranean, hypoxia-tolerant mole rat, Spalax.

Sch├╝lke S, Dreidax D, Malik A, Burmester T, Nevo E, Band M, Avivi A, Hankeln T.

Gene. 2012 Jun 1;500(2):199-206. doi: 10.1016/j.gene.2012.03.019. Epub 2012 Mar 13. Erratum in: Gene. 2014 Mar 1;537(1):176.

PMID:
22441129
9.

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity.

Resnick MA, Inga A.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9934-9. Epub 2003 Aug 8.

10.

The double benefit of Spalax p53: surviving underground hypoxia while defying lung cancer cells in vitro via autophagy and caspase-dependent cell death.

Ellis M, Stern O, Ashur-Fabian O.

Oncotarget. 2016 Sep 27;7(39):63242-63251. doi: 10.18632/oncotarget.11443.

11.

Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax.

Zhao Y, Tang JW, Yang Z, Cao YB, Ren JL, Ben-Abu Y, Li K, Chen XQ, Du JZ, Nevo E.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2146-51. doi: 10.1073/pnas.1522658112. Epub 2016 Feb 8.

13.

Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1 alpha.

Shams I, Avivi A, Nevo E.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9698-703. Epub 2004 Jun 21.

14.

Ontogenetic expression of erythropoietin and hypoxia-inducible factor-1 alpha genes in subterranean blind mole rats.

Shams I, Nevo E, Avivi A.

FASEB J. 2005 Feb;19(2):307-9. Epub 2004 Dec 1.

PMID:
15574488
15.

The muscle ankyrin repeat proteins are hypoxia-sensitive: in vivo mRNA expression in the hypoxia-tolerant blind subterranean mole rat, Spalax ehrenbergi.

Band M, Joel A, Avivi A.

J Mol Evol. 2010 Jan;70(1):1-12. doi: 10.1007/s00239-009-9306-6. Epub 2009 Dec 5.

PMID:
19967343
16.

The C terminus of p53 family proteins is a cell fate determinant.

Harms KL, Chen X.

Mol Cell Biol. 2005 Mar;25(5):2014-30.

17.
18.

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation.

Stommel JM, Wahl GM.

Cell Cycle. 2005 Mar;4(3):411-7. Epub 2005 Mar 2. Review.

PMID:
15684615
19.

Differential regulation of MDR1 transcription by the p53 family members. Role of the DNA binding domain.

Johnson RA, Shepard EM, Scotto KW.

J Biol Chem. 2005 Apr 8;280(14):13213-9. Epub 2005 Jan 5.

20.

Structural basis for gene activation by p53 family members.

Scoumanne A, Harms KL, Chen X.

Cancer Biol Ther. 2005 Nov;4(11):1178-85. Epub 2005 Nov 18. Review.

PMID:
16294021

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