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Items: 1 to 20 of 88

1.
3.
4.

G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation.

Luo J, Benovic JL.

J Biol Chem. 2003 Dec 19;278(51):50908-14. Epub 2003 Oct 13.

5.

Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia.

Lu A, Ran R, Parmentier-Batteur S, Nee A, Sharp FR.

J Neurochem. 2002 Apr;81(2):355-64.

6.

Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.

Guo F, Rocha K, Bali P, Pranpat M, Fiskus W, Boyapalle S, Kumaraswamy S, Balasis M, Greedy B, Armitage ES, Lawrence N, Bhalla K.

Cancer Res. 2005 Nov 15;65(22):10536-44.

7.

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.

Smith V, Sausville EA, Camalier RF, Fiebig HH, Burger AM.

Cancer Chemother Pharmacol. 2005 Aug;56(2):126-37. Epub 2005 Apr 20.

PMID:
15841378
8.
9.

Geldanamycin provides posttreatment protection against glutamate-induced oxidative toxicity in a mouse hippocampal cell line.

Xiao N, Callaway CW, Lipinski CA, Hicks SD, DeFranco DB.

J Neurochem. 1999 Jan;72(1):95-101.

10.

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.

Shen HY, He JC, Wang Y, Huang QY, Chen JF.

J Biol Chem. 2005 Dec 2;280(48):39962-9. Epub 2005 Oct 6.

11.

E1AF/PEA3 activates the Rho/Rho-associated kinase pathway to increase the malignancy potential of non-small-cell lung cancer cells.

Hakuma N, Kinoshita I, Shimizu Y, Yamazaki K, Yoshida K, Nishimura M, Dosaka-Akita H.

Cancer Res. 2005 Dec 1;65(23):10776-82.

12.

Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts.

Eiseman JL, Lan J, Lagattuta TF, Hamburger DR, Joseph E, Covey JM, Egorin MJ.

Cancer Chemother Pharmacol. 2005 Jan;55(1):21-32. Epub 2004 Aug 27.

PMID:
15338192
13.

Involvement of calcium-mediated reactive oxygen species in inductive GRP78 expression by geldanamycin in 9L rat brain tumor cells.

Sun FC, Shyu HY, Lee MS, Lee MS, Lai YK.

Int J Mol Sci. 2013 Sep 18;14(9):19169-85. doi: 10.3390/ijms140919169.

14.

Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells.

Kaarniranta K, Ryhänen T, Sironen RK, Suuronen T, Elo MA, Karjalainen HM, Lammi MJ, Teräsvirta M, Uusitalo H, Salminen A.

Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):126-31. Epub 2005 Apr 7.

PMID:
15950770
15.

Geldanamycin-associated inhibition of intracellular trafficking is attributed to a co-purified activity.

Barzilay E, Ben-Califa N, Supino-Rosin L, Kashman Y, Hirschberg K, Elazar Z, Neumann D.

J Biol Chem. 2004 Feb 20;279(8):6847-52. Epub 2003 Dec 1.

16.

Chaperones are the target in aloe-emodin-induced human lung nonsmall carcinoma H460 cell apoptosis.

Lai MY, Hour MJ, Wing-Cheung Leung H, Yang WH, Lee HZ.

Eur J Pharmacol. 2007 Nov 14;573(1-3):1-10. Epub 2007 Jul 12.

PMID:
17643413
17.

Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation.

Luppi F, Longo AM, de Boer WI, Rabe KF, Hiemstra PS.

Lung Cancer. 2007 Apr;56(1):25-33. Epub 2006 Dec 15.

PMID:
17175059
18.

Differential regulation of stress proteins by high hydrostatic pressure, heat shock, and unbalanced calcium homeostasis in chondrocytic cells.

Elo MA, Sironen RK, Kaarniranta K, Auriola S, Helminen HJ, Lammi MJ.

J Cell Biochem. 2000 Sep 14;79(4):610-9.

PMID:
10996852
19.

Effects of geldanamycin on HIF-1alpha mediated angiogenesis and invasion in prostate cancer cells.

Alqawi O, Moghaddas M, Singh G.

Prostate Cancer Prostatic Dis. 2006;9(2):126-35. Epub 2006 Jan 24.

PMID:
16432534
20.

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