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Items: 1 to 20 of 138

1.

Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 fusion protein.

Holmen SL, Robertson SA, Zylstra CR, Williams BO.

Biochem Biophys Res Commun. 2005 Mar 11;328(2):533-9.

PMID:
15694380
2.

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.

Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C.

Nature. 2001 May 17;411(6835):321-5.

PMID:
11357136
3.

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.

Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO.

J Biol Chem. 2002 Sep 20;277(38):34727-35. Epub 2002 Jul 16.

4.

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.

Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C.

Nature. 2002 Jun 6;417(6889):664-7. Epub 2002 May 26.

PMID:
12050670
7.

Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.

Bourhis E, Tam C, Franke Y, Bazan JF, Ernst J, Hwang J, Costa M, Cochran AG, Hannoush RN.

J Biol Chem. 2010 Mar 19;285(12):9172-9. doi: 10.1074/jbc.M109.092130. Epub 2010 Jan 21.

8.

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.

Semënov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X.

Curr Biol. 2001 Jun 26;11(12):951-61.

9.

Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK.

J Biol Chem. 2006 May 12;281(19):13247-57. Epub 2006 Mar 16.

10.

Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells.

Lyons JP, Mueller UW, Ji H, Everett C, Fang X, Hsieh JC, Barth AM, McCrea PD.

Exp Cell Res. 2004 Aug 15;298(2):369-87.

PMID:
15265686
11.

Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling.

Yamamoto H, Sakane H, Yamamoto H, Michiue T, Kikuchi A.

Dev Cell. 2008 Jul;15(1):37-48. doi: 10.1016/j.devcel.2008.04.015.

12.

Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling.

Wu W, Glinka A, Delius H, Niehrs C.

Curr Biol. 2000 Dec 14-28;10(24):1611-4.

13.

Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling.

Roman-Roman S, Shi DL, Stiot V, Haÿ E, Vayssière B, Garcia T, Baron R, Rawadi G.

J Biol Chem. 2004 Feb 13;279(7):5725-33. Epub 2003 Nov 24.

14.

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow.

Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA.

Nat Cell Biol. 2001 Jul;3(7):683-6.

PMID:
11433302
15.

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.

He X, Semenov M, Tamai K, Zeng X.

Development. 2004 Apr;131(8):1663-77. Review.

16.
17.

Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling.

Mao B, Niehrs C.

Gene. 2003 Jan 2;302(1-2):179-83.

PMID:
12527209
18.

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.

Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr.

Bone. 2008 Apr;42(4):669-80. doi: 10.1016/j.bone.2007.12.006. Epub 2007 Dec 27.

PMID:
18294945
19.

G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.

Liu T, DeCostanzo AJ, Liu X, Wang Hy, Hallagan S, Moon RT, Malbon CC.

Science. 2001 Jun 1;292(5522):1718-22.

20.

FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development.

Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE.

EMBO J. 2005 Jan 12;24(1):73-84. Epub 2004 Dec 9.

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