Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 101


Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival.

Patrussi L, Savino MT, Pellegrini M, Paccani SR, Migliaccio E, Plyte S, Lanfrancone L, Pelicci PG, Baldari CT.

Oncogene. 2005 Mar 24;24(13):2218-28.


Tyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activation.

Pacini S, Ulivieri C, Di Somma MM, Isacchi A, Lanfrancone L, Pelicci PG, Telford JL, Baldari CT.

J Biol Chem. 1998 Aug 7;273(32):20487-93.


p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells.

Patrussi L, Ulivieri C, Lucherini OM, Paccani SR, Gamberucci A, Lanfrancone L, Pelicci PG, Baldari CT.

Blood. 2007 Sep 15;110(6):1730-8. Epub 2007 May 30.


Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts.

Plyte S, Majolini MB, Pacini S, Scarpini F, Bianchini C, Lanfrancone L, Pelicci P, Baldari CT.

Oncogene. 2000 Mar 16;19(12):1529-37.


Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

Migliaccio E, Mele S, Salcini AE, Pelicci G, Lai KM, Superti-Furga G, Pawson T, Di Fiore PP, Lanfrancone L, Pelicci PG.

EMBO J. 1997 Feb 17;16(4):706-16.


Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes.

Sharma PM, Son HS, Ugi S, Ricketts W, Olefsky JM.

Mol Endocrinol. 2005 Feb;19(2):421-30. Epub 2004 Oct 14.


Interaction of Shc with Grb2 regulates association of Grb2 with mSOS.

Ravichandran KS, Lorenz U, Shoelson SE, Burakoff SJ.

Mol Cell Biol. 1995 Feb;15(2):593-600.


Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction.

Lennartsson J, Blume-Jensen P, Hermanson M, Pontén E, Carlberg M, Rönnstrand L.

Oncogene. 1999 Sep 30;18(40):5546-53.


Requirement for Shc in TCR-mediated activation of a T cell hybridoma.

Pratt JC, van den Brink MR, Igras VE, Walk SF, Ravichandran KS, Burakoff SJ.

J Immunol. 1999 Sep 1;163(5):2586-91.


A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.

van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.

Curr Biol. 1995 Apr 1;5(4):404-12.


p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells.

Arany I, Faisal A, Nagamine Y, Safirstein RL.

J Biol Chem. 2008 Mar 7;283(10):6110-7. doi: 10.1074/jbc.M708799200. Epub 2008 Jan 3.


Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes.

de Koning JP, Schelen AM, Dong F, van Buitenen C, Burgering BM, Bos JL, Löwenberg B, Touw IP.

Blood. 1996 Jan 1;87(1):132-40.

Supplemental Content

Support Center