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Items: 1 to 20 of 686

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Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling.

He X, Woodford-Thomas TA, Johnson KG, Shah DD, Thomas ML.

Eur J Immunol. 2002 Sep;32(9):2578-87.

6.

Subdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylation.

Felberg J, Lefebvre DC, Lam M, Wang Y, Ng DH, Birkenhead D, Cross JL, Johnson P.

J Biol Chem. 2004 Jan 30;279(5):3455-62. Epub 2003 Nov 17.

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Interactions of CD45-associated protein with the antigen receptor signaling machinery in T-lymphocytes.

Veillette A, Soussou D, Latour S, Davidson D, Gervais FG.

J Biol Chem. 1999 May 14;274(20):14392-9.

12.

CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line.

Koretzky GA, Kohmetscher M, Ross S.

J Biol Chem. 1993 Apr 25;268(12):8958-64.

13.

Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction.

Dornan S, Sebestyen Z, Gamble J, Nagy P, Bodnar A, Alldridge L, Doe S, Holmes N, Goff LK, Beverley P, Szollosi J, Alexander DR.

J Biol Chem. 2002 Jan 18;277(3):1912-8. Epub 2001 Nov 2.

14.

CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.

Wong NK, Lai JC, Birkenhead D, Shaw AS, Johnson P.

J Immunol. 2008 Nov 15;181(10):7033-43.

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The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line.

Peyron JF, Verma S, de Waal Malefyt R, Sancho J, Terhorst C, Spits H.

Int Immunol. 1991 Dec;3(12):1357-66.

PMID:
1838006
17.

Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck.

Danielian S, Alcover A, Polissard L, Stefanescu M, Acuto O, Fischer S, Fagard R.

Eur J Immunol. 1992 Nov;22(11):2915-21.

PMID:
1358625
18.

CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.

Ng DH, Jabali MD, Maiti A, Borodchak P, Harder KW, Brocker T, Malissen B, Jirik FR, Johnson P.

Biochem J. 1997 Nov 1;327 ( Pt 3):867-76.

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MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells.

Mukherjee P, Tinder TL, Basu GD, Gendler SJ.

J Leukoc Biol. 2005 Jan;77(1):90-9. Epub 2004 Oct 28.

PMID:
15513966
20.

Interaction of SAP-1, a transmembrane-type protein-tyrosine phosphatase, with the tyrosine kinase Lck. Roles in regulation of T cell function.

Ito T, Okazawa H, Maruyama K, Tomizawa K, Motegi S, Ohnishi H, Kuwano H, Kosugi A, Matozaki T.

J Biol Chem. 2003 Sep 12;278(37):34854-63. Epub 2003 Jul 1.

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