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Items: 1 to 20 of 144

1.

Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury.

Jacobson JR, Barnard JW, Grigoryev DN, Ma SF, Tuder RM, Garcia JG.

Am J Physiol Lung Cell Mol Physiol. 2005 Jun;288(6):L1026-32. Epub 2005 Jan 21.

2.

Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury.

Yao HW, Mao LG, Zhu JP.

Clin Exp Pharmacol Physiol. 2006 Sep;33(9):793-7.

PMID:
16922808
3.

Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion.

Naidu BV, Woolley SM, Farivar AS, Thomas R, Fraga C, Mulligan MS.

J Thorac Cardiovasc Surg. 2003 Aug;126(2):482-9.

4.

Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury.

Peng X, Hassoun PM, Sammani S, McVerry BJ, Burne MJ, Rabb H, Pearse D, Tuder RM, Garcia JG.

Am J Respir Crit Care Med. 2004 Jun 1;169(11):1245-51. Epub 2004 Mar 12.

PMID:
15020292
5.

N-acetyl cysteine attenuates acute lung injury in the rat.

Davreux CJ, Soric I, Nathens AB, Watson RW, McGilvray ID, Suntres ZE, Shek PN, Rotstein OD.

Shock. 1997 Dec;8(6):432-8.

PMID:
9421857
6.

Critical role for integrin-β4 in the attenuation of murine acute lung injury by simvastatin.

Chen W, Sammani S, Mitra S, Ma SF, Garcia JG, Jacobson JR.

Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15;303(4):L279-85. doi: 10.1152/ajplung.00361.2011. Epub 2012 Jun 8.

7.

The role of aquaporin-1 (AQP1) expression in a murine model of lipopolysaccharide-induced acute lung injury.

Su X, Song Y, Jiang J, Bai C.

Respir Physiol Neurobiol. 2004 Aug 20;142(1):1-11.

PMID:
15351300
8.

Long-term simvastatin attenuates lung injury and oxidative stress in murine acute lung injury models induced by oleic Acid and endotoxin.

Altintas ND, Atilla P, Iskit AB, Topeli A.

Respir Care. 2011 Aug;56(8):1156-63. doi: 10.4187/respcare.00770. Epub 2011 Mar 9.

9.

Simvastatin attenuates lipopolysaccharide-induced airway mucus hypersecretion in rats.

Ou XM, Wang BD, Wen FQ, Feng YL, Huang XY, Xiao J.

Chin Med J (Engl). 2008 Sep 5;121(17):1680-7.

PMID:
19024099
10.

Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation.

Grommes J, Vijayan S, Drechsler M, Hartwig H, Mörgelin M, Dembinski R, Jacobs M, Koeppel TA, Binnebösel M, Weber C, Soehnlein O.

PLoS One. 2012;7(6):e38917. doi: 10.1371/journal.pone.0038917. Epub 2012 Jun 11.

11.

Simvastatin suppresses lung inflammatory response in a rat cardiopulmonary bypass model.

Shao H, Shen Y, Liu H, Dong G, Qiang J, Jing H.

Ann Thorac Surg. 2007 Dec;84(6):2011-8.

PMID:
18036927
12.

Protective effect of purinergic agonist ATPgammaS against acute lung injury.

Kolosova IA, Mirzapoiazova T, Moreno-Vinasco L, Sammani S, Garcia JG, Verin AD.

Am J Physiol Lung Cell Mol Physiol. 2008 Feb;294(2):L319-24. Epub 2007 Nov 9.

13.

Oxidized phospholipids reduce vascular leak and inflammation in rat model of acute lung injury.

Nonas S, Miller I, Kawkitinarong K, Chatchavalvanich S, Gorshkova I, Bochkov VN, Leitinger N, Natarajan V, Garcia JG, Birukov KG.

Am J Respir Crit Care Med. 2006 May 15;173(10):1130-8. Epub 2006 Mar 2.

14.

Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2.

Tuomisto TT, Lumivuori H, Kansanen E, Häkkinen SK, Turunen MP, van Thienen JV, Horrevoets AJ, Levonen AL, Ylä-Herttuala S.

Cardiovasc Res. 2008 Apr 1;78(1):175-84. doi: 10.1093/cvr/cvn007. Epub 2008 Jan 10.

PMID:
18192240
15.

CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo.

Knuefermann P, Baumgarten G, Koch A, Schwederski M, Velten M, Ehrentraut H, Mersmann J, Meyer R, Hoeft A, Zacharowski K, Grohé C.

Respir Res. 2007 Oct 9;8:72.

16.

Reversal of elastase-induced pulmonary emphysema and promotion of alveolar epithelial cell proliferation by simvastatin in mice.

Takahashi S, Nakamura H, Seki M, Shiraishi Y, Yamamoto M, Furuuchi M, Nakajima T, Tsujimura S, Shirahata T, Nakamura M, Minematsu N, Yamasaki M, Tateno H, Ishizaka A.

Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L882-90. doi: 10.1152/ajplung.00238.2007. Epub 2008 Feb 29.

17.

Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injury.

Melo AC, Valença SS, Gitirana LB, Santos JC, Ribeiro ML, Machado MN, Magalhães CB, Zin WA, Porto LC.

Int Immunopharmacol. 2013 Sep;17(1):57-64. doi: 10.1016/j.intimp.2013.05.016. Epub 2013 Jun 6.

18.

Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1.

Birukova AA, Xing J, Fu P, Yakubov B, Dubrovskyi O, Fortune JA, Klibanov AM, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2010 Nov;299(5):L652-63. doi: 10.1152/ajplung.00202.2009. Epub 2010 Aug 20.

19.

Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats.

Giusti-Paiva A, Martinez MR, Felix JV, da Rocha MJ, Carnio EC, Elias LL, Antunes-Rodrigues J.

Shock. 2004 Mar;21(3):271-5.

PMID:
14770041
20.

Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin.

Jacobson JR, Dudek SM, Birukov KG, Ye SQ, Grigoryev DN, Girgis RE, Garcia JG.

Am J Respir Cell Mol Biol. 2004 May;30(5):662-70. Epub 2003 Nov 20.

PMID:
14630613

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