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Items: 1 to 20 of 82

1.

Pharmacokinetics and biodistribution of novel aptamer compositions.

Healy JM, Lewis SD, Kurz M, Boomer RM, Thompson KM, Wilson C, McCauley TG.

Pharm Res. 2004 Dec;21(12):2234-46.

PMID:
15648255
2.

Conjugation to polyethylene glycol polymer promotes aptamer biodistribution to healthy and inflamed tissues.

Boomer RM, Lewis SD, Healy JM, Kurz M, Wilson C, McCauley TG.

Oligonucleotides. 2005 Fall;15(3):183-95.

PMID:
16201906
3.

Pharmacologic and pharmacokinetic assessment of anti-TGFbeta2 aptamers in rabbit plasma and aqueous humor.

McCauley TG, Kurz JC, Merlino PG, Lewis SD, Gilbert M, Epstein DM, Marsh HN.

Pharm Res. 2006 Feb;23(2):303-11. Epub 2006 Jan 19.

PMID:
16411148
4.

Molar mass profiling of synthetic polymers by free-solution capillary electrophoresis of DNA-polymer conjugates.

Vreeland WN, Desruisseaux C, Karger AE, Drouin G, Slater GW, Barron AE.

Anal Chem. 2001 Apr 15;73(8):1795-803.

PMID:
11338593
5.

Pharmacokinetics and biodistribution of a nucleotide-based thrombin inhibitor in rats.

Reyderman L, Stavchansky S.

Pharm Res. 1998 Jun;15(6):904-10.

PMID:
9647357
6.
7.

PEG-doxorubicin conjugates: influence of polymer structure on drug release, in vitro cytotoxicity, biodistribution, and antitumor activity.

Veronese FM, Schiavon O, Pasut G, Mendichi R, Andersson L, Tsirk A, Ford J, Wu G, Kneller S, Davies J, Duncan R.

Bioconjug Chem. 2005 Jul-Aug;16(4):775-84.

PMID:
16029018
8.

The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of PEGylated poly l-lysine dendrimers.

Kaminskas LM, Boyd BJ, Karellas P, Krippner GY, Lessene R, Kelly B, Porter CJ.

Mol Pharm. 2008 May-Jun;5(3):449-63. doi: 10.1021/mp7001208. Epub 2008 Apr 5.

PMID:
18393438
9.

Characterization, efficacy, pharmacokinetics, and biodistribution of 5kDa mPEG modified tetrameric canine uricase variant.

Zhang C, Fan K, Luo H, Ma X, Liu R, Yang L, Hu C, Chen Z, Min Z, Wei D.

Int J Pharm. 2012 Jul 1;430(1-2):307-17. doi: 10.1016/j.ijpharm.2012.03.057. Epub 2012 Apr 5.

PMID:
22503989
10.

Lactoferrin conjugated with 40-kDa branched poly(ethylene glycol) has an improved circulating half-life.

Nojima Y, Suzuki Y, Yoshida K, Abe F, Shiga T, Takeuchi T, Sugiyama A, Shimizu H, Sato A.

Pharm Res. 2009 Sep;26(9):2125-32. doi: 10.1007/s11095-009-9925-z. Epub 2009 Jun 25.

PMID:
19554429
11.

PEGylation and biodistribution of an anti-MUC1 aptamer in MCF-7 tumor-bearing mice.

Da Pieve C, Blackshaw E, Missailidis S, Perkins AC.

Bioconjug Chem. 2012 Jul 18;23(7):1377-81. doi: 10.1021/bc300128r. Epub 2012 Jun 25.

PMID:
22708500
12.

Aptamer-enhanced laser desorption/ionization for affinity mass spectrometry.

Dick LW Jr, McGown LB.

Anal Chem. 2004 Jun 1;76(11):3037-41.

PMID:
15167780
13.

PEGylation of cholecystokinin prolongs its anorectic effect in rats.

León-Tamariz F, Verbaeys I, Van Boven M, De Cuyper M, Buyse J, Clynen E, Cokelaere M.

Peptides. 2007 May;28(5):1003-11. Epub 2007 Feb 15.

PMID:
17379357
14.

Anti-L-selectin aptamers: binding characteristics, pharmacokinetic parameters, and activity against an intravascular target in vivo.

Watson SR, Chang YF, O'Connell D, Weigand L, Ringquist S, Parma DH.

Antisense Nucleic Acid Drug Dev. 2000 Apr;10(2):63-75.

PMID:
10805157
15.

Liposomal topotecan formulation with a low polyethylene glycol grafting density: pharmacokinetics and antitumour activity.

Li C, Wang C, Yang H, Zhao X, Wei N, Cui J.

J Pharm Pharmacol. 2012 Mar;64(3):372-82. doi: 10.1111/j.2042-7158.2011.01422.x. Epub 2011 Dec 16.

PMID:
22309269
16.
17.

Pharmacokinetics and biodistribution of the camptothecin-polymer conjugate IT-101 in rats and tumor-bearing mice.

Schluep T, Cheng J, Khin KT, Davis ME.

Cancer Chemother Pharmacol. 2006 May;57(5):654-62. Epub 2005 Aug 26.

PMID:
16133526
18.

Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration.

Noll BO, McCluskie MJ, Sniatala T, Lohner A, Yuill S, Krieg AM, Schetter C, Davis HL, Uhlmann E.

Biochem Pharmacol. 2005 Mar 15;69(6):981-91.

PMID:
15748709
19.

Folate coupled poly(ethyleneglycol) conjugates of anionic poly(amidoamine) dendrimer for inflammatory tissue specific drug delivery.

Chandrasekar D, Sistla R, Ahmad FJ, Khar RK, Diwan PV.

J Biomed Mater Res A. 2007 Jul;82(1):92-103.

PMID:
17269145
20.

Thiolytically cleavable dithiobenzyl urethane-linked polymer-protein conjugates as macromolecular prodrugs: reversible PEGylation of proteins.

Zalipsky S, Mullah N, Engbers C, Hutchins MU, Kiwan R.

Bioconjug Chem. 2007 Nov-Dec;18(6):1869-78. Epub 2007 Oct 13.

PMID:
17935288

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