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Items: 1 to 20 of 135

1.

Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.

Hiesberger T, Shao X, Gourley E, Reimann A, Pontoglio M, Igarashi P.

J Biol Chem. 2005 Mar 18;280(11):10578-86. Epub 2005 Jan 12.

2.

Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice.

Hiesberger T, Bai Y, Shao X, McNally BT, Sinclair AM, Tian X, Somlo S, Igarashi P.

J Clin Invest. 2004 Mar;113(6):814-25.

3.

Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter.

Williams SS, Cobo-Stark P, Hajarnis S, Aboudehen K, Shao X, Richardson JA, Patel V, Igarashi P.

Am J Physiol Renal Physiol. 2014 Aug 1;307(3):F356-68. doi: 10.1152/ajprenal.00422.2013. Epub 2014 Jun 4.

4.

Roles of HNF-1beta in kidney development and congenital cystic diseases.

Igarashi P, Shao X, McNally BT, Hiesberger T.

Kidney Int. 2005 Nov;68(5):1944-7. Review.

5.

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA.

Hajarnis SS, Patel V, Aboudehen K, Attanasio M, Cobo-Stark P, Pontoglio M, Igarashi P.

J Biol Chem. 2015 Oct 9;290(41):24793-805. doi: 10.1074/jbc.M115.670646. Epub 2015 Aug 19.

6.

Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins.

Soutoglou E, Papafotiou G, Katrakili N, Talianidis I.

J Biol Chem. 2000 Apr 28;275(17):12515-20.

7.

Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1β.

Choi YH, McNally BT, Igarashi P.

Am J Physiol Renal Physiol. 2013 Jul 1;305(1):F100-10. doi: 10.1152/ajprenal.00582.2012. Epub 2013 May 8.

8.

Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.

Aboudehen K, Noureddine L, Cobo-Stark P, Avdulov S, Farahani S, Gearhart MD, Bichet DG, Pontoglio M, Patel V, Igarashi P.

J Am Soc Nephrol. 2017 Oct;28(10):2887-2900. doi: 10.1681/ASN.2016101095. Epub 2017 May 15.

PMID:
28507058
9.

Regulation of kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta.

Bai Y, Pontoglio M, Hiesberger T, Sinclair AM, Igarashi P.

Am J Physiol Renal Physiol. 2002 Oct;283(4):F839-51.

10.

Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative.

Yamagata K, Yang Q, Yamamoto K, Iwahashi H, Miyagawa J, Okita K, Yoshiuchi I, Miyazaki J, Noguchi T, Nakajima H, Namba M, Hanafusa T, Matsuzawa Y.

Diabetes. 1998 Aug;47(8):1231-5.

PMID:
9703322
11.

The transcriptional regulation of phosphoenolpyruvate carboxykinase gene in the kidney requires the HNF-1 binding site of the gene.

Cassuto H, Olswang Y, Heinemann S, Sabbagh K, Hanson RW, Reshef L.

Gene. 2003 Oct 30;318:177-84.

PMID:
14585510
12.

Activation of nicotinamide N-methyltransferase gene promoter by hepatocyte nuclear factor-1beta in human papillary thyroid cancer cells.

Xu J, Capezzone M, Xu X, Hershman JM.

Mol Endocrinol. 2005 Feb;19(2):527-39. Epub 2004 Oct 14.

PMID:
15486044
13.

Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3.

Ma Z, Gong Y, Patel V, Karner CM, Fischer E, Hiesberger T, Carroll TJ, Pontoglio M, Igarashi P.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20386-91. Epub 2007 Dec 12.

14.

Cystogenesis in ARPKD results from increased apoptosis in collecting duct epithelial cells of Pkhd1 mutant kidneys.

Hu B, He X, Li A, Qiu Q, Li C, Liang D, Zhao P, Ma J, Coffey RJ, Zhan Q, Wu G.

Exp Cell Res. 2011 Jan 15;317(2):173-87. doi: 10.1016/j.yexcr.2010.09.012. Epub 2010 Sep 25.

PMID:
20875407
15.

HNF-1beta regulates transcription of the PKD modifier gene Kif12.

Gong Y, Ma Z, Patel V, Fischer E, Hiesberger T, Pontoglio M, Igarashi P.

J Am Soc Nephrol. 2009 Jan;20(1):41-7. doi: 10.1681/ASN.2008020238. Epub 2008 Nov 12.

16.
18.

Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity.

Soutoglou E, Viollet B, Vaxillaire M, Yaniv M, Pontoglio M, Talianidis I.

EMBO J. 2001 Apr 17;20(8):1984-92.

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