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Items: 1 to 20 of 1623

1.

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM).

Taylor PA, Panoskaltsis-Mortari A, Freeman GJ, Sharpe AH, Noelle RJ, Rudensky AY, Mak TW, Serody JS, Blazar BR.

Blood. 2005 Apr 15;105(8):3372-80. Epub 2004 Dec 23.

2.

Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients.

Blazar BR, Sharpe AH, Chen AI, Panoskaltsis-Mortari A, Lees C, Akiba H, Yagita H, Killeen N, Taylor PA.

Blood. 2003 May 1;101(9):3741-8. Epub 2003 Jan 9.

3.

Contribution of B7RP-1/ICOS co-stimulation to lethal acute GVHD.

Fujimura J, Takeda K, Kaduka Y, Saito M, Akiba H, Yagita H, Yamashiro Y, Shimizu T, Okumura K.

Pediatr Transplant. 2010 Jun;14(4):540-8. doi: 10.1111/j.1399-3046.2009.01279.x. Epub 2010 Feb 1.

PMID:
20136724
4.

Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients.

Blazar BR, Kwon BS, Panoskaltsis-Mortari A, Kwak KB, Peschon JJ, Taylor PA.

J Immunol. 2001 Mar 1;166(5):3174-83.

5.

Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions.

Blazar BR, Lees CJ, Martin PJ, Noelle RJ, Kwon B, Murphy W, Taylor PA.

J Immunol. 2000 Nov 1;165(9):4901-9.

6.

Only therapeutic ICOS:ICOSL blockade alleviates acute graft versus host disease.

Mollweide A, Staege MS, Hoeschen C, Hideo Y, Burdach S, Richter GH.

Klin Padiatr. 2009 Nov-Dec;221(6):344-50. doi: 10.1055/s-0029-1239532. Epub 2009 Nov 4.

PMID:
19890785
8.

Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease.

Zhang Y, Joe G, Hexner E, Zhu J, Emerson SG.

J Immunol. 2005 Mar 1;174(5):3051-8.

10.

Opposing effects of anti-activation-inducible lymphocyte-immunomodulatory molecule/inducible costimulator antibody on the development of acute versus chronic graft-versus-host disease.

Ogawa S, Nagamatsu G, Watanabe M, Watanabe S, Hayashi T, Horita S, Nitta K, Nihei H, Tezuka K, Abe R.

J Immunol. 2001 Nov 15;167(10):5741-8.

12.

Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation.

Blazar BR, Taylor PA, Panoskaltsis-Mortari A, Buhlman J, Xu J, Flavell RA, Korngold R, Noelle R, Vallera DA.

J Immunol. 1997 Jan 1;158(1):29-39.

PMID:
8977172
13.

CD70 signaling is critical for CD28-independent CD8+ T cell-mediated alloimmune responses in vivo.

Yamada A, Salama AD, Sho M, Najafian N, Ito T, Forman JP, Kewalramani R, Sandner S, Harada H, Clarkson MR, Mandelbrot DA, Sharpe AH, Oshima H, Yagita H, Chalasani G, Lakkis FG, Auchincloss H Jr, Sayegh MH.

J Immunol. 2005 Feb 1;174(3):1357-64.

14.

L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection.

Taylor PA, Panoskaltsis-Mortari A, Swedin JM, Lucas PJ, Gress RE, Levine BL, June CH, Serody JS, Blazar BR.

Blood. 2004 Dec 1;104(12):3804-12. Epub 2004 Aug 3.

15.

Paradoxical effects of interleukin-18 on the severity of acute graft-versus-host disease mediated by CD4+ and CD8+ T-cell subsets after experimental allogeneic bone marrow transplantation.

Min CK, Maeda Y, Lowler K, Liu C, Clouthier S, Lofthus D, Weisiger E, Ferrara JL, Reddy P.

Blood. 2004 Nov 15;104(10):3393-9. Epub 2004 Jul 27.

16.

Inducible costimulator (ICOS) up-regulation on activated T cells in chronic graft-versus-host disease after dog leukocyte antigen-nonidentical hematopoietic cell transplantation: a potential therapeutic target.

Sato M, Storb R, Loretz C, Stone D, Mielcarek M, Sale GE, Rezvani AR, Graves SS.

Transplantation. 2013 Jul 15;96(1):34-41. doi: 10.1097/TP.0b013e318295c025.

19.

Infusion of anti-B7.1 (CD80) and anti-B7.2 (CD86) monoclonal antibodies inhibits murine graft-versus-host disease lethality in part via direct effects on CD4+ and CD8+ T cells.

Blazar BR, Sharpe AH, Taylor PA, Panoskaltsis-Mortari A, Gray GS, Korngold R, Vallera DA.

J Immunol. 1996 Oct 15;157(8):3250-9.

PMID:
8871619
20.

Expression level of costimulatory receptor ICOS is critical for determining the polarization of helper T cell function.

Watanabe S, Ogawa S, Hara Y, Tanabe K, Toma H, Abe R.

Transpl Immunol. 2006 Apr;15(4):255-63. Epub 2006 Feb 14.

PMID:
16635747

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