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Items: 1 to 20 of 94

1.

Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage.

Fumarola C, La Monica S, Guidotti GG.

J Cell Physiol. 2005 Jul;204(1):155-65.

PMID:
15605414
3.

Glutamine is a key regulator for amino acid-controlled cell growth through the mTOR signaling pathway in rat intestinal epithelial cells.

Nakajo T, Yamatsuji T, Ban H, Shigemitsu K, Haisa M, Motoki T, Noma K, Nobuhisa T, Matsuoka J, Gunduz M, Yonezawa K, Tanaka N, Naomoto Y.

Biochem Biophys Res Commun. 2005 Jan 7;326(1):174-80.

PMID:
15567168
4.

Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells.

Hidayat S, Yoshino K, Tokunaga C, Hara K, Matsuo M, Yonezawa K.

Biochem Biophys Res Commun. 2003 Feb 7;301(2):417-23.

PMID:
12565877
5.

Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.

Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS Jr, Lynch CJ.

J Cell Biochem. 2000 Sep 7;79(3):427-41.

PMID:
10972980
6.

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.

Beugnet A, Tee AR, Taylor PM, Proud CG.

Biochem J. 2003 Jun 1;372(Pt 2):555-66. Erratum in: Biochem J. 2003 Aug 1;373(Pt 3):999.

7.

Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes.

Kanazawa T, Taneike I, Akaishi R, Yoshizawa F, Furuya N, Fujimura S, Kadowaki M.

J Biol Chem. 2004 Feb 27;279(9):8452-9. Epub 2003 Nov 10.

8.
9.

Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.

Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR.

J Biol Chem. 2005 Jan 21;280(3):1838-48. Epub 2004 Nov 1.

10.

ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats.

Hu LY, Sun ZG, Wen YM, Cheng GZ, Wang SL, Zhao HB, Zhang XR.

Neuroscience. 2010 Sep 1;169(3):1046-62. doi: 10.1016/j.neuroscience.2010.05.046. Epub 2010 Jun 1.

PMID:
20678995
11.
12.

Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.

Ban H, Shigemitsu K, Yamatsuji T, Haisa M, Nakajo T, Takaoka M, Nobuhisa T, Gunduz M, Tanaka N, Naomoto Y.

Int J Mol Med. 2004 Apr;13(4):537-43.

PMID:
15010853
13.
14.

Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats.

Lynch CJ, Hutson SM, Patson BJ, Vaval A, Vary TC.

Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E824-35.

15.

Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver.

Ishiguro H, Katano Y, Nakano I, Ishigami M, Hayashi K, Honda T, Goto H, Bajotto G, Maeda K, Shimomura Y.

Life Sci. 2006 Jul 17;79(8):737-43. Epub 2006 Apr 17.

PMID:
16616211
16.

Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.

Christie GR, Hajduch E, Hundal HS, Proud CG, Taylor PM.

J Biol Chem. 2002 Mar 22;277(12):9952-7. Epub 2002 Jan 11.

17.

Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.

Ronellenfitsch MW, Brucker DP, Burger MC, Wolking S, Tritschler F, Rieger J, Wick W, Weller M, Steinbach JP.

Brain. 2009 Jun;132(Pt 6):1509-22. doi: 10.1093/brain/awp093. Epub 2009 May 4.

PMID:
19416948
18.

Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism.

Schriever SC, Deutsch MJ, Adamski J, Roscher AA, Ensenauer R.

J Nutr Biochem. 2013 May;24(5):824-31. doi: 10.1016/j.jnutbio.2012.04.018. Epub 2012 Aug 13.

PMID:
22898570
19.

Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.

Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS.

Cancer Res. 2005 Nov 1;65(21):9953-61.

20.

Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system.

Ijichi C, Matsumura T, Tsuji T, Eto Y.

Biochem Biophys Res Commun. 2003 Mar 28;303(1):59-64.

PMID:
12646166

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